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  • T77108Olinvacimab；化合物 OlinvacimabOlinvacimab

    Olinvacimab (TTAC-0001), a fully human anti-VEGFR2 monoclonal antibody, demonstrates antiangiogenic activity by inhibiting VEGF binding to KDR, with a dissociation constant (K d) of 0.23 nM. It is utilized in research for treating recurrent glioblastoma and breast cancer [1].

    价 格：￥电议型 号：T77108产 地：中国大陆

  • T76279L1Retatrutide sodium salt；Retatrutide钠盐Retatrutide sodium salt(2381089-83-2 free base)|||LY3437943 sod

    Retatrutide sodium salt is a potent triple agonist peptide for glucagon receptor (GCGR), glucose-dependent proinsulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R) Retatrutide sodium salt is used in the study of type 2 diabetes and obesity.

    价 格：￥电议型 号：T76279L1产 地：中国大陆

  • T76108Leucine dehydrogenase；化合物 Leucine dehydrogenaseLeucine dehydrogenase

    Leucine dehydrogenase, purified from Bacillus spheroides, catalyzes the oxidative deamination of L-leucine, L-valine, L-isoleucine, L-norvaline, L-alpha-aminobutyrate, and L-norleucine and the reductive amination of their keto analogues [1].

    价 格：￥电议型 号：T76108产 地：中国大陆

  • T7526884-B10；化合物 84-B1084-B10

    84-B10, a derivative of 3-phenylglutaric acid, inhibits cisplatin-induced tubular ferroptosis, attenuates mitochondrial damage and oxidative stress, and ameliorates acute kidney injury (AKI) resulting from cisplatin administration [1].

    价 格：￥电议型 号：T75268产 地：中国大陆

  • T75108LNP Lipid-1；化合物 LNP Lipid-1LNP Lipid-1

    LNP Lipid-1 (Method B), a lipid compound, plays a crucial role in the formulation of lipid nanoparticles compositions and exhibits potential for transporting biologically active substances, including small molecule agents, proteins, and nucleic acids [1] [2].

    价 格：￥电议型 号：T75108产 地：中国大陆

  • T74502Antibacterial agent 108；化合物 Antibacterial agent 108Antibacterial agent 108

    Compound 1h (Antibacterial agent 108) is a potent antibacterial agent, demonstrating a minimum inhibitory concentration (MIC) of 3 μM against both MRSA and antibiotic-resistant strains [1].

    价 格：￥电议型 号：T74502产 地：中国大陆

  • T74108ddTTP；化合物 ddTTPddTTP

    ddTTP, a 2´,3´-dideoxyribonucleoside 5´-triphosphate (ddNTP), serves as a chain-elongation inhibitor of DNA polymerase in DNA sequencing [1].

    价 格：￥电议型 号：T74108产 地：中国大陆

  • T7352Pridopidine；4-[3-(甲磺酰基)苯基]-1-丙基哌啶ACR16|||ASP2314|||FR310826；ACR16|||ASP2314|||FR310826|||4-[3-(甲磺酰基)

    Pridopidine (FR310826), a dopamine (DA) stabilizer, acts as a low affinity dopamine D2 receptor (D2R) antagonist, improves motor performance and shows neuroprotective effects in Huntington disease R6/2 mouse model.

    价 格：￥电议型 号：T7352产 地：中国大陆

  • T73369UR-MB108；化合物 UR-MB108UR-MB108

    UR-MB108 is a potent and selective inhibitor of ABCG2 (BCRP), displaying an IC50 value of 79 nM, and exhibits stability in blood plasma.

    价 格：￥电议型 号：T73369产 地：中国大陆

  • T73108EGFR-IN-30；化合物 EGFR-IN-30EGFR-IN-30

    EGFR-IN-30, a potent inhibitor of EGFR, exhibits IC50 values of 1-10 nM and <1 nM for EGFR (WT) and EGFR (L858R/T790M/C797S), respectively. This compound is of potential interest for research into diseases characterized by cell proliferation, such as cancer.

    价 格：￥电议型 号：T73108产 地：中国大陆

  • T72513SC 51089 free base；化合物 SC 51089 free baseSC 51089 free base

    SC 51089 free base is a selective antagonist of the prostaglandin E2 EP1 receptor, demonstrating neuroprotective activity. It exhibits binding affinities (Kis) of 1.3 μM for EP1, 11.2 μM for TP, 17.5 μM for EP3, and 61.1 μM for FP receptors, respectively.

    价 格：￥电议型 号：T72513产 地：中国大陆

  • T72108Werner syndrome RecQ helicase-IN-2；化合物 Werner syndrome RecQ helicase-IN-2Werner syndrome RecQ helica

    Werner syndrome RecQ helicase-IN-2 (example 57), a potent inhibitor of the Werner syndrome RecQ DNA helicase enzyme (WRN), holds potential for use in cancer research.

    价 格：￥电议型 号：T72108产 地：中国大陆

  • T71908NU1085；化合物 NU1085NU1085

    NU1085 is a potent poly(ADP-ribose) polymerase (PARP) inhibitors have been developed that potentiate the cytotoxicity of ionizing radiation and anticancer drugs. The biological effects of NU1085 [Ki = 6 nM], in combination with temozolomide (TM) or topotecan (TP) have been studied in 12 human tumor cell lines (lung, colon, ovary, and breast cancer). Cells were treated with increasing concentrations of TM or TP +/- NU1085 (10 microM) for 72 h.

    价 格：￥电议型 号：T71908产 地：中国大陆

  • T71382KRC-108；化合物 KRC-108KRC-108

    KRC-108 is a multiple kinase inhibitor. KRC-108 is a potent inhibitor of Ron, Flt3 and TrkA as well as c-Met. KRC-108 inhibited oncogenic c-Met M1250T and Y1230D more strongly than wild type c-Met. The anti-proliferative activity of KRC-108 was measured by performing a cytotoxicity assay on a panel of cancer cell lines. The GI(50) values (i.e., 50% inhibition of cell growth) for KRC-108 ranged from 0.01 to 4.22 μM for these cancer cell lines. KRC-108 was also effective for the inhibition of tumo

    价 格：￥电议型 号：T71382产 地：中国大陆

  • T71337AJ-108235；化合物 AJ-108235AJ-108235

    AJ-108235 is a novel inhibitor of long chain fatty acid elongase 6 (ELOVL6).

    价 格：￥电议型 号：T71337产 地：中国大陆

  • T71147PBS-1086；化合物 PBS-1086PBS-1086

    PBS-1086 is a novel dual inhibitor of the canonical and noncanonical NF-κB pathways, increasing the magnitude and duration of initial EGFR inhibitor response in multiple NSCLC models, decreasing PDHK1 expression, and suppressing phosphorylation of the PDHK1 protein substrate PDHA1 in a panel of PTEN-deficient cell lines.

    价 格：￥电议型 号：T71147产 地：中国大陆

  • T71108TLR7/8 agonist 1；化合物 TLR7/8 agonist 7dTLR7/8 agonist 1

    TLR7/8 agonist 1 is a toll-like receptor ( TLR7 )/ TLR8 dual-agonistic imidazoquinoline.

    价 格：￥电议型 号：T71108产 地：中国大陆

  • T71089PF-00956980；化合物 PF-956980PF-00956980

    PF-00956980 is a reversible pan-JAK inhibitor, exhibiting IC50 values of 2.2 μM for JAK1, 23.1 μM for JAK2, and 59.9 μM for JAK3. It is utilized in the study of lung and skin inflammatory diseases.

    价 格：￥电议型 号：T71089产 地：中国大陆

  • T71088AM-211 sodium；化合物 AM-211 sodiumAM-211 sodium

    AM-211 sodium is a novel and potent antagonist of the prostaglandin D2 receptor type 2. AM-211 is active in animal models of allergic inflammation. AM211 has high affinity for human, mouse, rat, and guinea pig DP2 and it shows selectivity over other prostanoid receptors and enzymes. AM211 exhibits good oral bioavailability in rats and dogs and dose-dependently inhibits 13,14-dihydro-15-keto-PGD(2)-induced leukocytosis in a guinea pig pharmacodynamic assay.

    价 格：￥电议型 号：T71088产 地：中国大陆

  • T71086IT-066 HCl；化合物 IT-066 HClIT-066 HCl

    IT-066 HCl is a histamine H2 receptor antagonist.

    价 格：￥电议型 号：T71086产 地：中国大陆

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