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  • T77109Omfiloctocog alfa；化合物 Omfiloctocog alfaOmfiloctocog alfa

    Omfiloctocog alfa (SCT-800), a recombinant factor VIII (FVIII), is an essential protein for blood coagulation and a critical element of the fluid phase blood coagulation system. It is utilized in the research of Hemophilia A [1] [2].

    价 格：￥电议型 号：T77109产 地：中国大陆

  • T76747Fletikumab；夫来库单抗Anti-IL-20|||NN-8226|||NNC 0109-0012；Anti-IL-20|||NN-8226|||NNC 0109-0012

    Fletikumab (NNC0109-0012) is a monoclonal antibody against IL-20 that is often used as an IL-20 inhibitor.Fletikumab is used in the study of rheumatoid arthritis and psoriasis.

    价 格：￥电议型 号：T76747产 地：中国大陆

  • T76109Nuclease S1；化合物 Nuclease S1Nuclease S1

    Nuclease S1, a specific endonuclease, degrades single-stranded DNA (ssDNA) and RNA, and can remove protruding single-strand ends from double-stranded DNA [1] [2].

    价 格：￥电议型 号：T76109产 地：中国大陆

  • T75109HECT E3-IN-1；化合物 HECT E3-IN-1HECT E3-IN-1

    HECT E3-IN-1 (compound 3) is a HECT E3 ligase inhibitor that impedes Ub binding at the non-covalent Ub-binding site of Nedd4-1 [1].

    价 格：￥电议型 号：T75109产 地：中国大陆

  • T75010TD1092；化合物 TD1092TD1092

    TD1092, a pan-IAP degrader, effectively degrades cIAP1, cIAP2, and XIAP, catalyzing the activation of Caspase 3/7 and fostering apoptosis in cancer cells through IAP degradation. It also obstructs the TNFα-mediated NF-κB pathway, diminishing the phosphorylation of IKK, IkBα, p65, and p38, and operates as a PROTAC. This compound is utilized in cancer research [1].

    价 格：￥电议型 号：T75010产 地：中国大陆

  • T74622Antibacterial agent 109；化合物 Antibacterial agent 109Antibacterial agent 109

    Compound C-2 (Antibacterial agent 109) is a potent antibacterial agent effective against both gram-positive and gram-negative bacteria. It is non-mutagenic and functions by inhibiting protein synthesis, specifically by preventing the extension of new peptide chains [1].

    价 格：￥电议型 号：T74622产 地：中国大陆

  • T74109Captopril EP Impurity B；化合物 Captopril EP Impurity BCaptopril EP Impurity B

    Captopril EP Impurity B, a degradation product of Captopril (SQ-14534), serves as a thiol-containing, competitive inhibitor of the angiotensin-converting enzyme (ACE), demonstrating oral activity and potent antihypertensive effects with an IC50 value of 0.025 μM [1] [2] [3].

    价 格：￥电议型 号：T74109产 地：中国大陆

  • T73512ZC0109；化合物 ZC0109ZC0109

    ZC0109, a dual inhibitor targeting IDO1 and Thioredoxin Reductase 1 (TrxR1) with IC50 values of 50 nM and 3.0 μM respectively, effectively promotes ROS accumulation and arrests the cell cycle at the G1/S phase, culminating in apoptosis of cancer cells.

    价 格：￥电议型 号：T73512产 地：中国大陆

  • T73109JNK-1-IN-1；化合物 JNK-1-IN-1JNK-1-IN-1

    JNK-1-IN-1 is an inhibitor specifically targeting JNK-1, also exhibiting inhibition of MKK7 with an IC50 value of 7.8μM. It binds to MKK7cp, further reinforcing its role as a JNK-1 inhibitor.

    价 格：￥电议型 号：T73109产 地：中国大陆

  • T72109Werner syndrome RecQ helicase-IN-3；化合物 Werner syndrome RecQ helicase-IN-3Werner syndrome RecQ helica

    Werner syndrome RecQ helicase-IN-3, a potent and orally active inhibitor of Werner syndrome RecQ helicase (WRN), exhibits anticancer and antiproliferative activities with an IC50 value of 0.06 ?M.

    价 格：￥电议型 号：T72109产 地：中国大陆

  • T7184Firsocostat；化合物ND-630ND-630|||NDI-010976|||GS-0976；ND-630|||NDI-010976|||GS-0976

    Firsocostat (GS-0976) is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively)

    价 格：￥电议型 号：T7184产 地：中国大陆

  • T71757SC-10914；化合物 SC-10914SC-10914

    SC10914 is a highly potent PARP inhibitor (PARP1 IC50 = 7.87 nM) with potent anti-proliferative activity against human BRCA deficient tumor cells (MDA-MB-436, BRCA1 deficient, IC50 = 4.03 nM, Capan-1 BRCA2 deficient, IC50 = 11.66 nM) and PTEN deficient tumor cells (HGC-27,PTEN deficient, IC50 = 0.35 μM). SC10914 showed potent anti-tumor activity in BRCA1/2 mutant tumor models and better pharmacokinetics profile has the potential to be selected as the clinical candidate for the treatment of treat

    价 格：￥电议型 号：T71757产 地：中国大陆

  • T71109BAY-386；化合物 BAY-386BAY-386

    BAY-386 is a PAR1 receptor inhibitor which suppresses activation of thrombin and platelet activity.

    价 格：￥电议型 号：T71109产 地：中国大陆

  • T71099LLL12；化合物 LLL12LLL12

    LLL12 is a small molecule inhibitor of STAT3 that inhibits STAT3 phosphorylation. LLL12 enhanced the inhibitory effect of Cisplatin and Paclitaxel on ovarian cancer cell formation, migration, and growth [1] .

    价 格：￥电议型 号：T71099产 地：中国大陆

  • T71098AZ3971；化合物 AZ3971AZ3971

    AZ3971 is a potent BACE1 inhibitor. AZ3971 blocks BACE1-mediated cleavage of APP and inhibits Aβ42 production HEK cells overexpressing the APP protein which carries the Swedish mutation (HEK.APPswe).

    价 格：￥电议型 号：T71098产 地：中国大陆

  • T71097DC-120；化合物 DC-120DC-120

    DC-120 is an ATP competitive AKT kinase inhibitor that suppressed proliferation and induced apoptosis in liver cancer cells both in vitro and in vivo. DC120 blocked the phosphorylation of downstream molecules in the AKT signal pathway in dose- and time-dependent manners both in vitro and in vivo. DC120 inhibits AKT activity in vitro with an EC(50) of 153 nM. DC120 at 20 mg/kg/day inhibited the CNE2 xenograft tumor growth with a treated group/control group ratio of 38.1%, accompanied by increas

    价 格：￥电议型 号：T71097产 地：中国大陆

  • T71096GCC-4401C methanesulfonate；化合物 GCC-4401C methanesulfonateGCC-4401C methanesulfonate

    GCC-4401C methanesulfonate is a factor Xa inhibitor similar to rivaroxaban that is currently under development for venous thromboembolic disease (VTE).

    价 格：￥电议型 号：T71096产 地：中国大陆

  • T71094CD4 (81-92)；化合物 CD4 (81-92)CD4 (81-92)

    CD4 (81-92) is a peptide that was previously found to inhibit gp120 binding, HIV-1 infectivity, and syncytium formation.

    价 格：￥电议型 号：T71094产 地：中国大陆

  • T71093SB-1578 citrate；化合物 SB-1578 citrateSB-1578 citrate

    SB-1578 citrate is a novel, orally bioavailable JAK2 inhibitor with specificity for JAK2 within the JAK family and also potent activity against FLT3 and c-Fms. SB1578 blocks the activation of these kinases and their downstream signaling in pertinent cells, leading to inhibition of pathological cellular responses. The biochemical and cellular activities of SB1578 translate into its high efficacy in two rodent models of arthritis.

    价 格：￥电议型 号：T71093产 地：中国大陆

  • T71092Proteasome-IN-3；化合物 Proteasome-IN-3Proteasome-IN-3

    Proteasome-IN-3 is an inhibitor of proteasome-associated DUBs.

    价 格：￥电议型 号：T71092产 地：中国大陆

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