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T35328H-1152 dihydrochlorideH 1152 dihydrochloride,H1152 dihydrochloride
H-1152 dihydrochloride is a specific inhibitor of Rho-associated protein kinase (ROCK) with an IC50 of 12 nM and a Ki of 1.6 nM. H-1152 dihydrochloride inhibits PKA, PKC, PKG, Aurora A and CaMKII with IC50 values of 3.03 μM, 5.68 μM, 0.360 μM, 0.745 μM and 0.180 μM, respectively.
价 格:¥电议型 号:T35328产 地:中国大陆
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T41180JQAD1JQAD1,JQAD-1
JQAD1 is a potent and selective histone acetyltransferase EP300 degrader (PROTAC?; DC50≤ 31.6 nM); comprises an EP300 inhibitor, A485, joined by a linker to a cereblon E3 ligase ligand. JQAD1 brings about degradation of EP300 in neuroblastoma cell lines in a proteasome-dependent manner. JQAD1 suppresses both H3K27ac and EP300 expression levels and induces apoptosis. JQAD1 suppresses tumors growth in NSG mice xenografted with Kelly cells. CRC and MYCN genes are downregulated in tumors treated wit
价 格:¥电议型 号:T41180产 地:中国大陆
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T11757KHK-IN-2KHK IN 2,KHKIN2
KHK-IN-2 is a selective inhibitor of ketohexokinase with an IC50 value of 0.45 μM.
价 格:¥电议型 号:T11757产 地:中国大陆
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T7554Substance P (7-11)Inhibitor,Substance P (7-11),inhibit,NK receptor,Neurokinin Receptor,Substance P (
Substance P 7-11(TFA) is a C-terminal fragment of Substance P .
价 格:¥电议型 号:T7554产 地:中国大陆
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TP2112LTC14012 acetateTC-14012 acetate,TC14012 acetate
TC14012 acetate is a serum-stable derivative of T140 which is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM. TC14012 is also a potent CXCR7 agonist with an EC50 of 350 nM for recruiting β-arrestin 2 to CXCR7. TC14012 has anti-cancer activity and anti-HIV activity.
价 格:¥电议型 号:TP2112L产 地:中国大陆
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TJS1159ChrysosplenetinP-glycoprotein,Cluster of differentiation 243,CYPs,Ferroptosis,Inhibitor,ABCB1,Chryso
1. Chrysosplenetin is a metabolic inhibitor of artemisinin.
价 格:¥电议型 号:TJS1159产 地:中国大陆
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T11158EGFR-IN-11EGFRIN11,EGFR IN 11
EGFR-IN-11 is a selective inhibitor of EGFR-tyrosine kinase and induces cell apoptosis. EGFR-IN-11 inhibits triple mutant EGFRL858R/T790M/C797S with an IC50 of 18 nM and arrests cell cycle at G0/G1.
价 格:¥电议型 号:T11158产 地:中国大陆
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T8119TH5487TH 5487,Inhibitor,TH5487,inhibit,TH-5487
TH5487 is an potent inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1)( IC50 of 342 nM)
价 格:¥电议型 号:T8119产 地:中国大陆
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T11097Drobuline hydrochlorideDrobuline hydrochloride
Drobuline hydrochloride is an anti-arrhythmic agent with cardiac depressant activity.
价 格:¥电议型 号:T11097产 地:中国大陆
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T9554SN-008STING,Stimulator of Interferon Genes,SN-011,TMEM173,MITA,inhibit,ERIS,SN008,Inhibitor,SN 008,M
SN-008 is a less active analog SN-011 which is a STING antagonist. SN-008 can be used as a negative control.
价 格:¥电议型 号:T9554产 地:中国大陆
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T6014911β-HSD1-IN-1111βHSD1IN11
11β-HSD1-IN-11 is a competitive 11β-HSD1 inhibitor with IC50s of 0.34 μM and 0.13 μM against rat and human 11β-HSD1, respectively.
价 格:¥电议型 号:T60149产 地:中国大陆
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TP1199LUrotensin I acetate (83930-33-0 Free base)Urotensin I acetate (83930330 Free base),Urotensin I aceta
Urotensin I acetate, a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC50s of 11.46, 9.36 and 9.85 for human CRF1, human CRF2 and rat CRF2α receptors in CHO cells, and Kis of 0.4, 1.8, and 5.7 nM for hCRF1, rCRF2α and mCRF2β receptors, respectively[1][2].
价 格:¥电议型 号:TP1199L产 地:中国大陆
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TP1116LKinetensin acetate(103131-69-7 free base)Kinetensin acetate(103131697 free base),Kinetensin acetate(
Kinetensin acetate is isolated from pepsin-treated human plasma.Kinetensin acetate is a neurotensin-like peptide.
价 格:¥电议型 号:TP1116L产 地:中国大陆
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TN1136Procyanidin A1Inhibitor,Proanthocyanidin A 1,Procyanidin A1,Procyanidin A 1,Protein kinase C,inhibit
Procyanidin A1 has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2+; influx from an internal store in RBL-2H3 cells.
价 格:¥电议型 号:TN1136产 地:中国大陆
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T8811Tuftsin 3TFATuftsin 3TFA
Tuftsin 3TFA is a tetrapeptide. It is a macrophage/microglial activator.
价 格:¥电议型 号:T8811产 地:中国大陆
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T60022WAY-604116WAY604116,WAY 604116
WAY-604116 has anti-inflammatory, antitumor and antiasthmatic effects.
价 格:¥电议型 号:T60022产 地:中国大陆
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T7111Tenofovir DisoproxilInhibitor,GS-4331,Reverse Transcriptase,Tenofovir Disoproxil,HIV,GS4331,Human im
Tenofovir Disoproxil is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
价 格:¥电议型 号:T7111产 地:中国大陆
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T11024DHODH-IN-15DHODH IN 15,DHODHIN15
DHODH-IN-15 is the hydroxyfuran analogue of A771726. DHODH-IN-15 is a dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 11 μM for rat liver DHODH. DHODH-IN-15 can be used for rheumatoid arthritis.
价 格:¥电议型 号:T11024产 地:中国大陆
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T135115-Aminouridine
5-Aminouridine modifies nucleobases and is incorporated into the target DNA. 5-Aminouridine inhibits the growth of tumors, viruses, and fungi.
价 格:¥电议型 号:T13511产 地:中国大陆
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TN12553-O-Acetyl-11-hydroxy-beta-boswellic acidLipoxygenase,3OAcetyl11hydroxybetaboswellic acid,LOX,Inhibi
3-O-Acetyl-11-hydroxy-beta-boswellic acid is the precursor of 3-O-acetyl-9, 11-dehydro-beta-boswellic acid(a 5-lipoxygenase inhibitor ).
价 格:¥电议型 号:TN1255产 地:中国大陆