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  • T78111NCS-382 sodium；化合物 NCS-382 sodiumNCS-382 sodium

    NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological disease research [1].

    价 格：￥电议型 号：T78111产 地：中国大陆

  • T78080PSB-1114 triethylamine；化合物 PSB-1114 triethylaminePSB-1114 triethylamine

    PSB-1114 triethylamine is a potent, enzymatically stable, P2Y2 receptor agonist with a 134 nM EC50, exhibiting greater than 50-fold selectivity over P2Y4 (EC50 of 9.3 μM) and P2Y6 (EC50 of 7.0 μM) receptors [1].

    价 格：￥电议型 号：T78080产 地：中国大陆

  • T78075GBT1118；化合物 GBT1118GBT1118

    GBT1118 is a potent, orally active compound that serves as an allosteric modulator of hemoglobin oxygen affinity, enhancing tolerance to severe hypoxia [1].

    价 格：￥电议型 号：T78075产 地：中国大陆

  • T77412Lupartumab；鲁帕妥单抗BAY 1112623；BAY 1112623

    Lupartumab (BAY 1112623) is an anti-LYPD3 (C4.4A) monoclonal antibody that can be used to synthesize antibody-active molecular couplers that can be used to study LYPD3-associated tumor diseases.

    价 格：￥电议型 号：T77412产 地：中国大陆

  • T77111Omodenbamab；化合物 OmodenbamabOmodenbamab

    Omodenbamab, a humanized monoclonal antibody targeting Staphylococcal protein A (SpA), exhibits a dissociation constant (K D) of 0.0467 nM, effectively countering a crucial S. aureus evasion strategy by focusing on the cell wall component Protein A (SpA). It is applicable in the study of S. aureus bloodstream infections [1].

    价 格：￥电议型 号：T77111产 地：中国大陆

  • T76111Hexokinase (ScHEX1)；化合物 Hexokinase (ScHEX1)Hexokinase (ScHEX1)

    Hexokinase (ScHEX1), a glycolytic enzyme, is inhibited by n-acetylglucosamine, which causes it to detach from the mitochondrial outer membrane. This detachment activates the NLRP3 inflammasome [1].

    价 格：￥电议型 号：T76111产 地：中国大陆

  • T75910GR231118 TFA；化合物 GR231118 TFAGR231118 TFA

    GR231118 TFA, a neuropeptide Y C-terminus analogue, acts as a potent, competitive, and relatively selective antagonist at the human neuropeptide YY receptor, exhibiting a pKi of 10.4. It serves as a strong agonist at the human neuropeptide YY4 receptor with a pEC50 of 8.6 and a pKi of 9.6, while demonstrating weak agonistic activity at both human and rat neuropeptide YY2 and YY5 receptors. Additionally, this compound shows high affinity for the mouse neuropeptide YY6 receptor, with a pKi value o

    价 格：￥电议型 号：T75910产 地：中国大陆

  • T75861ANQ-11125 TFA；化合物 ANQ-11125 TFAANQ-11125 TFA

    ANQ-11125 TFA is a potent, selective motilin antagonist, exhibiting a pKd of 8.24. It effectively inhibits motilide-induced contractions in rabbit models, as demonstrated in vitro [1] [2].

    价 格：￥电议型 号：T75861产 地：中国大陆

  • T7584zanubrutinib；泽布替尼BGB-3111；赞鲁替尼|||BGB-3111|||泽布替尼

    Zanubrutinib (BGB-3111) is an inhibitor of Bruton tyrosine kinase (BTK).

    价 格：￥电议型 号：T7584产 地：中国大陆

  • T7566L1GRGDSPK acetate；GRGDSPK醋酸盐GRGDSPK acetate(111119-28-9 Free base)；GRGDSPK acetate(111119-28-9 Free ba

    GRGDSPK acetate shows inhibitory activity against integrin-fibronectin binding and can be used in research on integrins in bone formation and resorption.

    价 格：￥电议型 号：T7566L1产 地：中国大陆

  • T7566LGRGDSPK 2TFA(111119-28-9(free base))；化合物GRGDSPK 2TFAEMD 56574；EMD 56574

    GRGDSPK 2TFA(111119-28-9(free base)) (EMD 56574) is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.

    价 格：￥电议型 号：T7566L产 地：中国大陆

  • T7556611-Oxomogroside II A1；化合物 11-Oxomogroside II A111-Oxomogroside II A1

    11-Oxomogroside II A1 (compound 7), an oxidized cucurbitin derived from the ethanol extract of Rohanberry fruit, serves as an inhibitor for the activation of Epstein-Barr virus (EBV) early antigen (EBV-EA) triggered by 12-O-tetradecanoylphorbol-13-acetate (TPA). Additionally, it has a modest ability to inhibit the activation of (±)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor [1].

    价 格：￥电议型 号：T75566产 地：中国大陆

  • T75111LNP Lipid-4；化合物 LNP Lipid-4LNP Lipid-4

    LNP Lipid-4 (Compound 8-8) is a lipid compound with a crucial role in the synthesis of lipid nanoparticle compositions, demonstrating potential for the transport of biologically active substances [1].

    价 格：￥电议型 号：T75111产 地：中国大陆

  • T74642DB1113；化合物 DB1113DB1113

    DB1113 (Example 24) is a bifunctional compound designed for the targeted degradation of various kinases. It effectively degrades a range of kinases, including ABL1, ABL2, BLK, CDK11B, CDK4, CSK, EPHA3, FER, GAK, LIMK1, MAP3K20, MAP4K1, MAP4K2, MAP4K3, MAP4K5, MAPK14, MAPK7, MAPK8, MAPK9, MAPKAPK2, MAPKAPK3, NLK, PDIK1L, PTK2B, RIPK1, RPS6KA1, RPS6KA3, SIK2, SIK3, STK35, TNK2, and ULK1. This capability positions DB1113 as a valuable tool for research into diseases or disorders associated with abe

    价 格：￥电议型 号：T74642产 地：中国大陆

  • T74111N-Methyl pemetrexed；化合物 N-Methyl pemetrexedN-Methyl pemetrexed

    N-Methyl pemetrexed, an impurity found in Pemetrexed, serves as an antifolate cytotoxic agent utilized in cancer research [1].

    价 格：￥电议型 号：T74111产 地：中国大陆

  • T73220RO5461111；化合物 RO5461111RO5461111

    RO5461111, a highly specific and orally active Cathepsin S antagonist, exhibits potent inhibitory effects with IC50 values of 0.4 nM (human Cathepsin S) and 0.5 nM (murine Cathepsin S), respectively. It effectively suppresses the activation of antigen-specific T cells and B cells, and can ameliorate pulmonary inflammation and lupus nephritis.

    价 格：￥电议型 号：T73220产 地：中国大陆

  • T73111IDO1-IN-17；化合物 IDO1-IN-17IDO1-IN-17

    IDO1-IN-17 (I-4) is an IDO1 inhibitor, with an IC 50 of 0.44 μM in hela cells [1] .

    价 格：￥电议型 号：T73111产 地：中国大陆

  • T72111Ala-Ala-Pro-Val-chloromethylketone；化合物 Ala-Ala-Pro-Val-chloromethylketoneAAPV-CMK；AAPV-CMK

    Ala-Ala-Pro-Val-chloromethylketone serves as an irreversible inhibitor of human neutrophil elastase (NE), utilized in researching chronic inflammatory airway diseases.

    价 格：￥电议型 号：T72111产 地：中国大陆

  • T71503IND31119；化合物 IND31119IND31119

    IND31119 is a novel selective inhibitor of PfHsp90, bypassing its highly similar human orthologs.

    价 格：￥电议型 号：T71503产 地：中国大陆

  • T71119Netarsudil free base；化合物 Netarsudil free baseNetarsudil free base

    Netarsudil, also known as AR-11324, is a Rho-associated protein kinase inhibitor. Netarsudil is potential useful for treating glaucoma and?/or reducing intraocular pressure. Netarsudil Increases Outflow Facility in Human Eyes Through Multiple Mechanisms. Netarsudil inhibited kinases ROCK1 and ROCK2 with a Ki of 1?nM each, disrupted actin stress fibers and focal adhesions in TM cells with IC50s of 79 and 16?nM, respectively, and blocked the profibrotic effects of TGF-β2 in HTM cells. Netarsudi

    价 格：￥电议型 号：T71119产 地：中国大陆

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