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  • T77118Plozalizumab；洛扎利珠单抗MLN-1202；MLN-1202

    Plozalizumab (MLN-1202) is a humanized selective and potent anti-CCR2 antibody.Plozalizumab has antitumor activity.Plozalizumab is used in the study of malignant melanoma.

    价 格：￥电议型 号：T77118产 地：中国大陆

  • T76118Malate dehydrogenase；化合物 Malate dehydrogenaseMalate dehydrogenase

    Malate dehydrogenase catalyzes the mutual conversion of oxaloacetate and malate, and is associated with the oxidation/reduction of dinucleotide coenzymes [1] .

    价 格：￥电议型 号：T76118产 地：中国大陆

  • T75910GR231118 TFA；化合物 GR231118 TFAGR231118 TFA

    GR231118 TFA, a neuropeptide Y C-terminus analogue, acts as a potent, competitive, and relatively selective antagonist at the human neuropeptide YY receptor, exhibiting a pKi of 10.4. It serves as a strong agonist at the human neuropeptide YY4 receptor with a pEC50 of 8.6 and a pKi of 9.6, while demonstrating weak agonistic activity at both human and rat neuropeptide YY2 and YY5 receptors. Additionally, this compound shows high affinity for the mouse neuropeptide YY6 receptor, with a pKi value o

    价 格：￥电议型 号：T75910产 地：中国大陆

  • T75887[Ala113]MBP(104-118) TFA；化合物 [Ala113]MBP(104-118) TFA[Ala113]MBP(104-118) TFA

    [Ala113]MBP(104-118) TFA is a peptide inhibitor operating noncompetitively against protein kinase C (PKC), exhibiting inhibitory concentrations (IC50) in the range of 28-62 μM [1].

    价 格：￥电议型 号：T75887产 地：中国大陆

  • T75886[Ala107]MBP(104-118) TFA；化合物 [Ala107]MBP(104-118) TFA[Ala107]MBP(104-118) TFA

    [Ala107]MBP(104-118) TFA is a noncompetitive peptide inhibitor of protein kinase C (PKC), exhibiting IC50 values between 46-145 μM.

    价 格：￥电议型 号：T75886产 地：中国大陆

  • T75649Rivulariapeptolides 1185；化合物 Rivulariapeptolides 1185Rivulariapeptolides 1185

    Rivulariapeptolides 1185, a highly potent and selective serine protease inhibitor, exhibits IC50 values of 13.17 nM for chymotrypsin, 23.59 nM for elastase, and 55.26 nM for proteinase K [1].

    价 格：￥电议型 号：T75649产 地：中国大陆

  • T75118AN15368；化合物 AN15368AN15368

    AN15368, an orally administered small-molecule precursor, undergoes activation by parasite carboxypeptidase, yielding a product that interferes with the messenger RNA processing pathway in T. cruzi. This compound shows promise for both preventing and investigating potential treatments for Chagas disease [1].

    价 格：￥电议型 号：T75118产 地：中国大陆

  • T74118Roxatidine；化合物 RoxatidineRoxatidine

    Roxatidine, the active metabolite of Roxatidine acetate hydrochloride, serves as a histamine H2-receptor antagonist and exhibits anti-ulcer properties. It functions by suppressing the release of histamine, thereby inhibiting proton secretion, and also reduces the production of VEGF-1, a key indicator of inflammation and angiogenesis. This compound demonstrates an anti-allergic inflammatory effect [1].

    价 格：￥电议型 号：T74118产 地：中国大陆

  • T7334NP118809；化合物NP11880939-1B4；39-1B4|||1-【4-(二苯甲基)-1-哌嗪基】-3,3-二苯基-1-丙酮

    NP118809 (39-1B4) is a potent N-type calcium channel blocker(IC50 : 0.11 μM).

    价 格：￥电议型 号：T7334产 地：中国大陆

  • T73297TDI-11861；化合物 TDI-11861TDI-11861

    TDI-11861, a second-generation soluble Adenylyl Cyclase (sAC, ADCY10) inhibitor, demonstrates slow dissociation rates and effectively inhibits sAC activity in cells, evidenced by an IC50 value of 5.5 nM.

    价 格：￥电议型 号：T73297产 地：中国大陆

  • T73118PI3K-IN-28；化合物 PI3K-IN-28PI3K-IN-28

    PI3K-IN-28 is a potent PI3K inhibitor demonstrating high efficacy and lower toxicity in MCF-10a models. It exhibits half-maximal inhibitory concentration (IC50, μM) values of 5.8, 2.3, and 7.9. With a selectivity index (SI) of 39, PI3K-IN-28 emerges as a promising lead compound for the optimization of anticancer agents.

    价 格：￥电议型 号：T73118产 地：中国大陆

  • T72979LEM-14-1189；化合物LEM-14-1189LEM-14-1189

    Lem-14-1189, a LEM-14 derivative, is a potent NSD inhibitor of the nuclear receptor binding SET domain, and has inhibitory effects on NSD1, NSD2, and NSD3, with IC50 of 418 μM, 111 μM, and 60 μM, respectively. LEM-14-1189 has potential anticancer activity and can be used to study multiple myeloma (MM) and diseases of the blood system.

    价 格：￥电议型 号：T72979产 地：中国大陆

  • T71189RX 809055AX；化合物 RX 809055AXRX 809055AX

    RX 809055AX is a long lasting opioid antagonist at mu and delta receptors.

    价 格：￥电议型 号：T71189产 地：中国大陆

  • T71188LY2780301；化合物 LY2780301LY2780301

    LY2780301 is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor LY2780301 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway, thereby leading to inhibition of cell proliferation and the induction of apoptosis in tumor cells. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signa

    价 格：￥电议型 号：T71188产 地：中国大陆

  • T71187Foretinib phosphate；化合物 Foretinib phosphateForetinib phosphate

    Foretinib phosphate is an orally bioavailable small molecule with potential antineoplastic activity. MET/VEGFR2 inhibitor GSK1363089 binds to and selectively inhibits hepatocyte growth factor (HGF) receptor c-MET and vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of tumor angiogenesis, tumor cell proliferation and metastasis. The proto-oncogene c-MET has been found to be over-expressed in a variety of cancers.

    价 格：￥电议型 号：T71187产 地：中国大陆

  • T71186ORM-13070；化合物 ORM-13070ORM-13070

    ORM-13070 is a selective antagonist radioligand for the α2C adrenoceptor subtype. ORM-13070 C-11 is under investigation in clinical trial.

    价 格：￥电议型 号：T71186产 地：中国大陆

  • T71185Indotecan hydrochloride；化合物 Indotecan hydrochlorideIndotecan hydrochloride

    Indotecan hydrochloride is a novel selective and potent topoisomerase I inhibitor with potential anticancer activitity.

    价 格：￥电议型 号：T71185产 地：中国大陆

  • T71184ARQ-736；化合物 ARQ-736ARQ-736

    ARQ 736 is a potent and selective BRAF inhibitor. ARQ 736 is selectively potent in killing cancer cell lines harboring at least one mutated BRAF allele. BRAF mutations were detected in over 60% of melanomas and may account for a significant proportion of colon cancer patients whose tumors are resistant to anti-EGFR therapy. The B-Raf protein is a key signaling molecule in the mitogen activated protein kinase (MAPK) signaling pathway and has been implicated in the pathogenesis of a variety of ca

    价 格：￥电议型 号：T71184产 地：中国大陆

  • T71183Simpinicline citrate；化合物 Simpinicline citrateSimpinicline citrate

    Simpinicline citrate is a nicotinic acetylcholine receptor (nAChR) agonist.

    价 格：￥电议型 号：T71183产 地：中国大陆

  • T71182N 0745；化合物 N 0745N 0745

    N 0745 inhibits 2-[125I]-iodomelatonin binding to median eminence/pars tuberalis membranes with an affinity similar to that of melatonin.

    价 格：￥电议型 号：T71182产 地：中国大陆

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