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T61368FPI-1602;化合物 FPI-1602FPI-1602
FPI-1602 is a β-lactamase inhibitor with strong antimicrobial activity against Pseudomonas aeruginosa, Escherichia coli, and Enterobacter species [1].
价 格:¥电议型 号:T61368产 地:中国大陆
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T61367HIF-2α-IN-6;化合物 HIF-2α-IN-6HIF-2α-IN-6
HIF-2α-IN-6 (117) is a HIF-2α inhibitor [1].
价 格:¥电议型 号:T61367产 地:中国大陆
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T61366F-17;化合物 F-17F-17
F-17 is a promising virulence factor inhibitor, displaying substantial inhibitory effects on biofilm formation, elastase activity, pyocyanin production, and swarming motility. Additionally, F-17 exhibits a strong binding affinity towards LasR and PqsR. Notably, F-17 does not exhibit any discernible cytotoxicity [1].
价 格:¥电议型 号:T61366产 地:中国大陆
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T61365Peficitinib hydrochloride;化合物 Peficitinib hydrochloridePeficitinib hydrochloride
Peficitinib hydrochloride, also known as ASP015K, is an orally active JAK inhibitor compound. It exhibits inhibitory activity against JAK1, JAK2, JAK3, and Tyk2, with IC 50 values of 3.9, 5.0, 0.7, and 4.8 nM, respectively.
价 格:¥电议型 号:T61365产 地:中国大陆
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T61364LmCPB-IN-1;化合物 LmCPB-IN-1LmCPB-IN-1
LmCPB-IN-1 (compound 35) is a highly effective and reversible covalent inhibitor of Leishmania mexicana cysteine protease B (LmCPB). It exhibits a strong binding affinity with a pK i value of 9.7 [1].
价 格:¥电议型 号:T61364产 地:中国大陆
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T61363CXCR4 antagonist 8;化合物 CXCR4 antagonist 8CXCR4 antagonist 8
CXCR4 antagonist 8 (Compound 3) is a potent inhibitor of CXCR4. It demonstrates an IC50 value of 57 nM in CXCR4 antagonism. In addition, it effectively inhibits the increase in cytosolic calcium induced by CXCL12 with an IC50 value of 0.24 nM. Furthermore, Compound 3 shows efficacy in the inhibition of CXCL12/CXCR4-mediated cell migration [1].
价 格:¥电议型 号:T61363产 地:中国大陆
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T61362CDK5-IN-3;化合物 CDK5-IN-3CDK5-IN-3
CDK5-IN-3 (compound 11) is a highly potent and selective inhibitor of CDK5, demonstrating significant inhibition with IC50 values of 0.6 nM and 18 nM for CDK5/p25 and CDK2/CycA, respectively. This compound holds promise for further investigation in the context of autosomal dominant polycystic kidney disease (ADPKD) research [1].
价 格:¥电议型 号:T61362产 地:中国大陆
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T61361BRD-8899;化合物 BRD-8899BRD-8899
BRD-8899 is a STK33 inhibitor, with an IC 50 of 11 nM [1].
价 格:¥电议型 号:T61361产 地:中国大陆
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T61360ARN25068;化合物ARN25068ARN25068
ARN25068 is a potent inhibitor of GSK-3β, FYN, and DYRK1A protein kinases, exerting its activity in the sub-micromolar range. This compound effectively addresses tau hyperphosphorylation [1].
价 格:¥电议型 号:T61360产 地:中国大陆
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T6136Canertinib卡纽替尼PD-183805|||CI-1033|||卡纽替尼
Canertinib (CI-1033) is a pan-erbB tyrosine kinase inhibitor which work against esophageal squamous cell carcinoma in vitro and in vivo. Canertinib treatment significantly affects tumour metabolism, proliferation and hypoxia as determined by PET.
价 格:¥电议型 号:T6136产 地:中国大陆
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T6127Rucaparib Phosphate;瑞卡帕布磷酸盐AG-014699 phosphate|||PF-01367338|||AG-014699|||PF-01367338 phosphate;AG-
Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP (Ki: 1.4 nM for PARP1) that is used in clinical therapy to sensitize cancer cells to chemotherapy.
价 格:¥电议型 号:T6127产 地:中国大陆
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T61136Enpp-1-IN-11;化合物 Enpp-1-IN-11Enpp-1-IN-11
Enpp-1-IN-11 (compound 23) is a highly potent inhibitor of Ecto-nucleotide pyrophosphatase/phosphodiesterases 1 (ENPP1), with a Ki value of 45 nM. It demonstrates excellent stability in human and mouse plasma and exhibits low clearance in both human and mouse liver microsomes. Enpp-1-IN-11 holds promise for anticancer research [1].
价 格:¥电议型 号:T61136产 地:中国大陆
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T5136Kongensin A;化合物 T5136Kongensin A
Kongensin A is an effective heat shock protein 90 (HSP90) inhibitor that has potential anti-necroptosis and anti-inflammation applications.
价 格:¥电议型 号:T5136产 地:中国大陆
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T4692Protein kinase inhibitors 1 hydrochlorid;化合物T4692Protein kinase inhibitors 1 hydrochlorid (1365986-4
Protein kinase inhibitors 1 hydrochlorid (Protein kinase inhibitors 1 hydrochlorid (1365986-44-2(free base))) is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.
价 格:¥电议型 号:T4692产 地:中国大陆
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T4463Rucaparib;瑞卡帕布AG-14447|||PF-01367338|||AG014699;AG-14447|||PF-01367338|||瑞卡帕布|||AG014699
Rucaparib (PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, and also shows binding affinity to eight other PARP.
价 格:¥电议型 号:T4463产 地:中国大陆
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T41369(S)-Butaprost free acid;化合物 (S)-Butaprost free acid(S)-Butaprost free acid
(S)-Butaprost (free acid) is a potent and highly selective EP2 receptor agonist[1].
价 格:¥电议型 号:T41369产 地:中国大陆
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T413681,2-Dipalmitoyl-3-oleoylglycerol;化合物 1,2-Dipalmitoyl-3-oleoylglycerol1,2-Dipalmitoyl-3-oleoylglycero
1,2-Dipalmitoyl-3-oleoylglycerol has a wide range of applications in life science related research.
价 格:¥电议型 号:T41368产 地:中国大陆
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T413671,7-Dimethyluric acid;化合物 1,7-Dimethyluric acid1,7-Dimethyluric acid
1,7-Dimethyluric acid has a wide range of applications in life science related research.
价 格:¥电议型 号:T41367产 地:中国大陆
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T4136512S-HHT;化合物 12S-HHT12S-HHT
12S-HHT has a wide range of applications in life science related research.
价 格:¥电议型 号:T41365产 地:中国大陆
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T413631-Oxo Ibuprofen;化合物 1-Oxo Ibuprofen1-Oxo Ibuprofen
1-Oxo Ibuprofen is a useful organic compound for research related to life sciences. The catalog number is T41363 and the CAS number is 65813-55-0.
价 格:¥电议型 号:T41363产 地:中国大陆