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T61382Fasudil dihydrochloride；化合物 Fasudil dihydrochlorideFasudil dihydrochloride
Fasudil dihydrochloride, also known as HA-1077 and AT877, is a nonspecific inhibitor of RhoA/ROCK. It exhibits inhibitory effects on protein kinases, including ROCK1 with a Ki value of 0.33 μM, as well as ROCK2, PKA, PKC, and PKG with IC 50 values of 0.158 μM, 4.58 μM, 12.30 μM, and 1.650 μM, respectively. Additionally, Fasudil dihydrochloride demonstrates potent Ca 2+ channel blocking activity and acts as a vasodilator [1] [2] [3].
价 格：￥电议型 号：T61382产 地：中国大陆
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T61381Loxapine hydrochloride；化合物 Loxapine hydrochlorideLoxapine hydrochloride
Loxapine hydrochloride is a dibenzoxazepine anti-psychotic agent that exerts its effects through oral administration, functioning as an inhibitor of dopamine and an antagonist of 5-HT receptors [1] [4].
价 格：￥电议型 号：T61381产 地：中国大陆
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T61380Carpro-AM1；化合物 Carpro-AM1Carpro-AM1
Carpro-AM1 is a compound that acts as a dual inhibitor of both fatty acid amide hydrolase (FAAH) and substrate-selective cyclooxygenase (COX). It exhibits potent inhibitory activity against FAAH, with an IC50 value of 94 nM [1].
价 格：￥电议型 号：T61380产 地：中国大陆
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T6138TCS 359化合物TCS 359FLT3 Inhibitor
TCS 359 (FLT3 Inhibitor) is a potent FLT3 inhibitor with IC50 of 42 nM.
价 格：￥电议型 号：T6138产 地：中国大陆
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T61138Bevantolol；化合物 BevantololBevantolol
Bevantolol, a selective β-1 adrenoceptor antagonist, is utilized for the investigation of angina pectoris and hypertension [1].
价 格：￥电议型 号：T61138产 地：中国大陆
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T60265NV-5138 hydrochloride；化合物 NV-5138 hydrochlorideNV-5138 hydrochloride
NV-5138 hydrochloride is a leucine analog and is the first selective and orally active brain mTORC1 activator, binding to Sestrin2. NV-5138 hydrochloride can be used in the research of antidepressants [1] [2].
价 格：￥电议型 号：T60265产 地：中国大陆
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T5S1389Escin IB七叶皂苷B七叶皂苷B|||七叶皂苷 IB
Escin Ib inhibits gastric emptying, at least in part, mediated by capsaicin-sensitive sensory nerves, to stimulate the synthesis and/or release of dopamine, to act through central dopamine2 receptor, which in turn causes the release of PGs.
价 格：￥电议型 号：T5S1389产 地：中国大陆
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T5447Anle138b；化合物Anle138bAnle138b
Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson´s disease
价 格：￥电议型 号：T5447产 地：中国大陆
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T5324BI 01383298；化合物BI 01383298BI 01383298
BI 01383298 is a selective inhibitor of the sodium-citrate co-transporter (SLC13A5).
价 格：￥电议型 号：T5324产 地：中国大陆
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T5138BMS-986142；化合物BMS-986142BMS-986142
BMS-986142 is a potent and highly selective reversible BTK inhibitor (IC50: 0.5 nM).
价 格：￥电议型 号：T5138产 地：中国大陆
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T5129SRI-011381 hydrochloride；化合物SRI-011381 hydrochlorideSRI-011381 hydrochloride [1629138-41-5(free base
SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer´s disease.
价 格：￥电议型 号：T5129产 地：中国大陆
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T4S1387Isoescin IA七叶皂苷C七叶皂苷C|||异七叶皂苷 IA
Isoescin IA is a triterpenoid saponin isolated from the seeds of Aesculus chinensis. It has anti-HIV-1 protease activity.
价 格：￥电议型 号：T4S1387产 地：中国大陆
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T4S1383Escin IA；七叶皂苷AAescin IA|||Escin IA;Aescin IA|||Escin IA；Aescin IA|||Escin IA;Aescin IA|||Escin IA
Escin IA (Escin IA;Aescin IA) is a triterpene saponin isolated from horse chestnut, which inhibits HIV-1 protease with IC50 values of 35 μM. Escin IA has anti-TNBC metastasis activity, and its action mechanisms involved inhibition of epithelial-mesenchymal transition process by down-regulating LOXL2 expression[1][2].
价 格：￥电议型 号：T4S1383产 地：中国大陆
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T4436RO1138452；化合物RO1138452CAY10441；CAY10441
RO1138452 (CAY10441) is a selective and orally bioavailable antagonist of prostacyclin receptor (pKi: 8.3). It antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase, blocking cyclic AMP accumulation in a dose-dependent manner. Likewise, it inhibits the binding of tritiated iloprost to rodent neuroblastoma cells with a Ki of about 1.5 nM. At levels between 2-20 mg/kg in rats, CAY10441 shows significant analgesic activity in standard antinociceptive assays [
价 格：￥电议型 号：T4436产 地：中国大陆
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T4283SRI-011381；化合物SRI011381SRI-011381
SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer´s disease.
价 格：￥电议型 号：T4283产 地：中国大陆
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T4138UCPH-101；化合物UCPH101UCPH 101；UCPH 101
UCPH-101 is an inhibitor of excitatory amino acid transporter subtype 1 (EAAT1) with an IC50 of 0.66 μM.
价 格：￥电议型 号：T4138产 地：中国大陆
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T41138Prosaikogenin H；前柴胡皂苷H；柴胡次皂苷HProsaikogenin H
Prosaikogenin H, an intestinal metabolite derived from saikosaponin, exhibits weak hemolytic activity.
价 格：￥电议型 号：T41138产 地：中国大陆
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T401382,3-Dibromoacrylic acid；2,3-二溴丙烯酸2,3-Dibromoacrylic acid
2,3-Dibromoacrylic acid, an unsaturated carboxylic acid derivative, enriches the chemical profile of acrylic acid—the simplest form of such compounds—by integrating dibromo functionalities, serving as a versatile chemical intermediate.
价 格：￥电议型 号：T40138产 地：中国大陆
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T39138Muscotoxin A；Muscotoxin AMuscotoxin A
Muscotoxin A is an ADC cytotoxin with lipopeptide properties that effectively permeabilizes mammalian cell membranes, ultimately inducing necrotic cell death.
价 格：￥电议型 号：T39138产 地：中国大陆
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T38960LQL-X-138 HCl；QL-X-138 盐酸盐QL-X-138 HCl（1469988-63-3 Free base）；QL-X-138 HCl（1469988-63-3 Free base）
QL-X-138 HCl is a novel selective and highly potent BTK/MNK dual-kinase inhibitor with anticancer activity that binds covalently to BTK and noncovalently to MNK. QL-X-138 HCl inhibited BTK, MNK1, and MNK2 kinases. QL-X-138 HCl has anti-dengue virus 2 activity and shows anti-proliferative activity in acute myeloid leukemia cells. QL-X-138 HCl can be used to study lymphoma and leukemia.
价 格：￥电议型 号：T38960L产 地：中国大陆
