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  • T63193IDH2R140Q-IN-1；化合物 IDH2R140Q-IN-1IDH2R140Q-IN-1

    IDH2R140Q-IN-1 is a potent inhibitor of IDH2R140Q (IC50: 6.1 nM) and can be used in studies of acute myeloid leukemia.

    价 格：￥电议型 号：T63193产 地：中国大陆

  • T62193PD-1/PD-L1-IN 5；化合物 PD-1/PD-L1-IN 5PD-1/PD-L1-IN 5

    PD-1/PD-L1-IN 5 is a potent PD-1/PD-L1 protein/protein interaction inhibitor (IC50 ≤ 100 nM).

    价 格：￥电议型 号：T62193产 地：中国大陆

  • T61939Topo I/COX-2-IN-1；化合物 Topo I/COX-2-IN-1Topo I/COX-2-IN-1

    Topo I/COX-2-IN-1 (1H-30) is a potent Topo I/COX-2 inhibitor with the IC50 of 0.24 μM and 4.42 μM for COX-2 and Topo I, respectively. Topo I/COX-2-IN-1 induces apoptosis and inhibits migration of cancer cells, shows anti-cancer activity.

    价 格：￥电议型 号：T61939产 地：中国大陆

  • T61938HSP90-IN-12；化合物 HSP90-IN-12HSP90-IN-12

    Vibsanin A analog C (VAC) is an anti-cancer compound, which shows anti-proliferative effect on various cancer cell lines, and the anti-proliferative activity is the strongest among vibsanin A analogues. VAC fluctuated the amount of HSP90-related proteins in cells and showed an inhibitory effect on HSP90-mediated luciferase refolding in vitro.

    价 格：￥电议型 号：T61938产 地：中国大陆

  • T61937DNA Gyrase-IN-3；化合物 DNA Gyrase-IN-3DNA Gyrase-IN-3

    DNA Gyrase-IN-3 (Compound 28) is an inhibitor of bacterial DNA gyrase B. The IC50 of DNA Gyrase-IN-3 inhibits Escherichia coli DNA rotatase is 5.41-15.64 μM. DNA Gyrase-IN-3 shows anti-tuberculosis and antibacterial activity.

    价 格：￥电议型 号：T61937产 地：中国大陆

  • T61936AChE-IN-7；化合物 AChE-IN-7AChE-IN-7

    AChE-IN-7 (Compound 16) is a selective and effective acetylcholinesterase inhibitor with IC50 of 0.045 μM and 19.68 μ M for eeAChE and eeBuChE, respectively. AChE-IN-7 has high permeability of blood-brain barrier. AChE-IN-7 is safe in vivo and in vitro, and exhibits good overall pharmacokinetics and high bioavailability (F=55.5%).

    价 格：￥电议型 号：T61936产 地：中国大陆

  • T61935B-Raf IN 9；化合物 B-Raf IN 9B-Raf IN 9

    B-Raf IN 9 (compound 8b) is an effective B-Raf inhibitor (IC50=24.79 nM). B-Raf IN 9 blocks cell cycle at G2/M phase and induces apoptosis. B-Raf IN 9 showed potent anti-tumor activity on human prostate cancer PC-3 cells (IC50=7.83 μM).

    价 格：￥电议型 号：T61935产 地：中国大陆

  • T61934Repinotan；瑞匹诺坦BAY x 3702 free base；BAY x 3702 free base

    Repinotan (BAY x 3702 free base) is an orally active and selective 5-HT1A receptor agonist that crosses the blood-brain barrier (BBB), has neuroprotective activity, antagonizes morphine-induced depression of ventilation in anesthetized rats, and can be used in studies of acute ischemic stroke and traumatic brain injury.

    价 格：￥电议型 号：T61934产 地：中国大陆

  • T61933MK-0159；化合物 MK-0159MK-0159

    MK-0159 is an orally available, highly potent CD38 inhibitor with myocardial injury protection for the study of cardiac ischemia and reperfusion injury.

    价 格：￥电议型 号：T61933产 地：中国大陆

  • T61932Nesuparib；化合物NesuparibJPI-547/OCN-201；JPI-547/OCN-201

    Nesuparib (JPI-547/OCN-201) is a potent PARP inhibitor with inhibitory effects on PARP and TNKS1.Nesuparib has antitumor activity and can be used in the treatment of tumors, endocrine and metabolic disorders, genitourinary disorders, and can be used in the study of neuropathic pain, neurodegenerative disorders, and cardiovascular diseases.

    价 格：￥电议型 号：T61932产 地：中国大陆

  • T61931IRAK4-IN-10；化合物 IRAK4-IN-10IRAK4-IN-10

    IRAK4-IN-10 (compound 75) is an effective IRAK4 inhibitor (IC50 is 1.5 nM), which can block the MyD88-dependent signal pathway. IRAK4-IN-10 has research potential in inflammatory diseases, autoimmune diseases and cancer.

    价 格：￥电议型 号：T61931产 地：中国大陆

  • T6193Dovitinib Dilactic Acid；化合物Dovitinib Dilactic AcidDovitinib (TKI-258) Dilactic Acid|||TKI258 Dilacti

    Dovitinib Dilactic Acid (Dovitinib (TKI-258) Dilactic Acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.

    价 格：￥电议型 号：T6193产 地：中国大陆

  • T6158LDN-193189 HCl；化合物LDN-193189 HClLDN193189 Hydrochloride；LDN193189 Hydrochloride

    LDN-193189 HCl (LDN193189 Hydrochloride) is a selective BMP type I receptor kinases inhibitor.

    价 格：￥电议型 号：T6158产 地：中国大陆

  • T6131Pimasertib；化合物PimasertibAS703026|||MSC1936369B|||SAR 245509；AS703026|||MSC1936369B|||N-[(2S)-2,3-二羟基

    Pimasertib (AS703026) is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.

    价 格：￥电议型 号：T6131产 地：中国大陆

  • T61193DDX3-IN-2；化合物 DDX3-IN-2DDX3-IN-2

    DDX3-IN-2, a potent inhibitor of DEADbox polypeptide 3 (DDX3), demonstrates remarkable activity against the target with an IC50 value of 0.3 μM. Notably, this compound exhibits a wide range of antiviral effects, showcasing its efficacy against various viral strains. Importantly, DDX3-IN-2 exhibits the potential to overcome resistance observed in the context of HIV [1].

    价 格：￥电议型 号：T61193产 地：中国大陆

  • T6087AZD 6482；化合物AZD6482KIN 193|||AZD6482；KIN 193|||AZD6482

    AZD 6482 (AZD6482) is a potent and selective p110β inhibitor with IC50 of 0.69 nM and a PI3Kβ inhibitor with IC50 of 10 nM.

    价 格：￥电议型 号：T6087产 地：中国大陆

  • T60193CB-5339；化合物CB-5339CB-5339

    p97-IN-1 is a potent inhibitor of p97 with an IC 50 <30 nM [1].

    价 格：￥电议型 号：T60193产 地：中国大陆

  • T60031NRX-1933；化合物NRX-1933NRX-1933

    NRX-1933 is a molecular glue and enhances the interaction between an oncogenic transcription factor, β-Catenin, and its cognate E3 ligase, SCFβ-TrCP.

    价 格：￥电议型 号：T60031产 地：中国大陆

  • T5640GSK2193874；化合物GSK2193874GSK2193874

    GSK2193874 was identified as a selective, orally active TRPV4 blocker.

    价 格：￥电议型 号：T5640产 地：中国大陆

  • T5193Danirixin；化合物DanirixinGSK1325756；GSK1325756

    Danirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).

    价 格：￥电议型 号：T5193产 地：中国大陆

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