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T6203Saxagliptin;沙格列汀BMS-477118|||Onglyza;BMS-477118|||沙克列汀|||Onglyza|||沙格列汀
Saxagliptin (BMS-477118) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.
价 格:¥电议型 号:T6203产 地:中国大陆
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T61355APX2039;化合物APX2039APX-2039|||APX 2039;APX-2039|||APX 2039
APX2039 is an orally active fungal Gwt1 enzyme inhibitor and a prodrug of the novel Gwt2096 inhibitor APX1.APX2039 exhibits potent anti-Kryptococcal activity against C. neoformans and C. gattii.APX2039 exhibits potent antifungal activity and blocks the localization of GPI (glycosylphosphatidylinositol) anchored cell wall mannoproteins. APX2039 has potent antifungal activity and blocks the localization of GPI (glycosylphosphatidylinositol)-anchored cell wall mannoproteins.APX2039 can be used to s
价 格:¥电议型 号:T61355产 地:中国大陆
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T61203ALK5-IN-8;化合物 ALK5-IN-8ALK5-IN-8
ALK5-IN-8 is a highly effective inhibitor of TGFβRI (ALK5). It hinders the phosphorylation of ALK5 on downstream signaling proteins (Smad2 or Smad3) by obstructing the interaction between TGFβRI and ligands. Consequently, it disrupts or prevents TGF-β signaling. ALK5-IN-8 shows promise in the study of diverse diseases associated with ALK5-mediated pathways[1].
价 格:¥电议型 号:T61203产 地:中国大陆
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T60384VU0420373;化合物 VU0420373VU0420373
VU0420373 is a potent activator of the heme sensor system (HssRS), demonstrating an EC50 of 10.7 μM and a pEC50 of 4.97. It induces heme biosynthesis and exhibits toxicity towards fermenting S. aureus [1].
价 格:¥电议型 号:T60384产 地:中国大陆
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T6026CPI-203化合物CPI203CPI 203|||CPI203
CPI-203 is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).
价 格:¥电议型 号:T6026产 地:中国大陆
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T60203INCB13739;化合物 INCB13739INCB13739
INCB13739 is an orally active, potent, selective, and tissue-specific inhibitor of 11β-HSD1 (11β-hydroxysteroid dehydrogenase 1), demonstrating IC50 values of 3.2 nM (11β-HSD1 enzymatic) and 1.1 nM (11β-HSD1 PBMC). It is utilized in research for type 2 diabetes mellitus (T2DM) and obesity [1].
价 格:¥电议型 号:T60203产 地:中国大陆
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T5400Q203;化合物Q203IAP6|||Telacebec;IAP6|||Telacebec
Q203 (Telacebec) is a novel potent anti-tuberculosis agent targeting cytochrome b subunit qcrB and inhibits M. tuberculosis H37Rv (MIC50: 2.7 nM).
价 格:¥电议型 号:T5400产 地:中国大陆
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T5343UAMC-3203;化合物UAMC-3203UAMC 3203|||UAMC3203;UAMC 3203|||UAMC3203
UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).
价 格:¥电议型 号:T5343产 地:中国大陆
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T5265Phenylacetylglutamine;N-苯乙酰基-L-谷氨酰胺NSC 203800|||Phenyl-Ac-Gln-OH|||Phenylacetyl-L-glutamine;NSC 2038
Phenylacetylglutamine (NSC 203800)is a normal constituent of human urine, but other mammals such as the dog, cat, rat, monkey, sheep, and horse do not excrete this compound. Phenylacetylglutamine is a major nitrogenous metabolite that accumulates in uremia. Phenylacetylglutamine also is a microbial metabolite found in Christensenellaceae, Lachnospiraceae, and Ruminococcaceae.
价 格:¥电议型 号:T5265产 地:中国大陆
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T5203Sodium Tartrate;酒石酸钠Sodium Tartrate
Sodium Tartrate is a food additive, used as an emulsifier and binding agent in food products.
价 格:¥电议型 号:T5203产 地:中国大陆
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T4696BMS202 hydrochloride (1675203-84-5(free base));化合物BMS202 hydrochloridePD-1/PD-L1 inhibitor 2 hydroch
BMS202 hydrochloride (1675203-84-5(free base)) (PD-1/PD-L1 inhibitor 2 hydrochloride) is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L1. Binding of BMS202 promotes PD-L1 dimerisation and blocks the PD-L1/ PD1 interaction.
价 格:¥电议型 号:T4696产 地:中国大陆
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T4611EN300-203561;化合物EN300-203561EN300-203561
EN300-203561 has a wide range of applications in life science related research.
价 格:¥电议型 号:T4611产 地:中国大陆
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T4435E7820;化合物E7820ER68203-00;ER68203-00
E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).
价 格:¥电议型 号:T4435产 地:中国大陆
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T4399ML239;化合物ML239CID-49843203;CID-49843203
ML239 (CID-49843203) is a potent and selective inhibitor of breast cancer stem cells, with an IC50 of 1.16 μM.
价 格:¥电议型 号:T4399产 地:中国大陆
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T4306CCG-203971;化合物CCG203971CCG203971;CCG203971
CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM. This compound also inhibits PC-3 cell migration (IC50: 4.2 μM), as determined by a scratch wound assay. CCG-203971(CCG203971) causes no cytotoxicity when evaluated by the WST-1 assay. It is well tolerated in normal mice up to doses of 100 mg/kg given intraperitoneally over five days.
价 格:¥电议型 号:T4306产 地:中国大陆
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T4210SAR-20347;化合物SAR20347SAR20347;SAR20347
SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).
价 格:¥电议型 号:T4210产 地:中国大陆
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T412031R,3R-RSL3;1R,3R-RSL31R,3R-RSL3;1R,3R-RSL3
1R,3R-RSL3 is a negative control for1S, 3R-RSL3.
价 格:¥电议型 号:T41203产 地:中国大陆
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T40203AZD-CO-Ph-PEG4-Ph-CO-AZD;AZD-CO-Ph-PEG4-Ph-CO-AZDAZD-CO-Ph-PEG4-Ph-CO-AZD;AZD-CO-Ph-PEG4-Ph-CO-AZD
AZD-CO-Ph-PEG4-Ph-CO-AZD is a bis-β-lactam linker, commonly employed in the synthesis of antibody-siRNA conjugates.
价 格:¥电议型 号:T40203产 地:中国大陆
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T38791LY3020371;LY3020371LY3020371
LY3020371 is a highly potent and selective antagonist targeting the glutamate (mGlu) 2/3 receptor, showcasing excellent inhibition at Ki values of 5.26 nM and 2.50 nM for hmGluR2 and hmGluR3, respectively. With its remarkable affinity and specificity, LY3020371 serves as a valuable tool in depression research.
价 格:¥电议型 号:T38791产 地:中国大陆
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T38203Gastrin I, rat;Gastrin I (rat)Gastrin I, rat
Gastrin I, rat is a peptide hormone that effectively stimulates gastric acid secretion.
价 格:¥电议型 号:T38203产 地:中国大陆