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T4071Repotrectinib;化合物TPX0005TPX-0005|||TPX 0005|||TPX0005;TPX-0005|||TPX 0005|||TPX0005
Repotrectinib (TPX-0005) is a potent ALK/ROS1/TRK inhibitor, with IC50 of 1.01 nM, 5.3 nM, 1.08 nM and 1.26 nM for WT ALK, SRC, ALK L1196M and ALK G1202R, respectively.
价 格:¥电议型 号:T4071产 地:中国大陆
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T407093-Diethylamino-1-propanol;3-二乙氨基-1-丙醇3-Diethylamino-1-propanol
3-Diethylamino-1-propanol exhibits anticonvulsant effects.
价 格:¥电议型 号:T40709产 地:中国大陆
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T40708Neoanhydropodophyllol;NeoanhydropodophyllolNeoanhydropodophyllol
Neoanhydropodophyllol, a cyclolignan derivative, exhibits potent antineoplastic activity by exerting cytotoxic effects on various cancer cell lines including leukemia, lung carcinoma, and colon carcinoma.
价 格:¥电议型 号:T40708产 地:中国大陆
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T40707Methyl-PEG4-acyl chloride;Methyl-PEG4-acyl chlorideMethyl-PEG4-acyl chloride;Methyl-PEG4-acyl chlori
Methyl-PEG4-acyl chloride is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T40707产 地:中国大陆
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T40706Heliotrine N-oxide;Heliotrine N-oxideHeliotrine N-oxide
Heliotrine N-oxide is the pyrrolizidine alkaloid (PA) N-oxide counterpart of Heliotrine. It induces the generation of pyrrolic DNA adducts, potentially initiating PA-induced liver tumors in vivo.
价 格:¥电议型 号:T40706产 地:中国大陆
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T40705m-Tolualdehyde;间甲苯甲醛m-Tolualdehyde
m-Tolualdehyde, also known as 3-Methylbenzaldehyde, is a chemical compound in the tolualdehyde family featuring a methyl substituent positioned at the 3-position. It finds application as a food additive.
价 格:¥电议型 号:T40705产 地:中国大陆
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T40703trans-4-Nitrocinnamoyl chloride;trans-4-Nitrocinnamoyl chloridetrans-4-Nitrocinnamoyl chloride
trans-4-Nitrocinnamoyl chloride is used as derivatization reagent.
价 格:¥电议型 号:T40703产 地:中国大陆
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T40702Decaethylene glycol dodecyl ether;Decaethylene glycol dodecyl etherPEG10-dodecyl;PEG10-dodecyl
Decaethylene glycol dodecyl ether, a PEG-based PROTAC linker, finds utility in PROTAC synthesis.
价 格:¥电议型 号:T40702产 地:中国大陆
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T40701Ezeprogind;EzeprogindAZP-2006;AZP-2006
Ezeprogind (AZP-2006) is an orally active neurotrophic inducer that effectively addresses the underlying factors contributing to neurodegeneration, with a broad scope extending beyond the conventional targets like Abeta protein and tau protein. Exhibiting potent neuroprotective properties, Ezeprogind is a valuable tool for studying a range of neurological disorders, including progressive supranuclear palsy (PSP), tauopathies, Alzheimer´s disease, Parkinson´s disease, and others.
价 格:¥电议型 号:T40701产 地:中国大陆
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T40700IKK-IN-3;IKK-IN-3IKK-IN-3
IKK-IN-3 is a highly potent and selective inhibitor of IkappaB kinase 2 (IKK2 or IKKβ). It exhibits impressive inhibitory activity against IKK2 (IC50 = 19 nM), while also demonstrating significant efficacy against IKK1 (or IKKα) with an IC50 value of 400 nM.
价 格:¥电议型 号:T40700产 地:中国大陆
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T4070Glycocholic Acid Sodium Salt;甘氨胆酸钠盐Glycocholate Sodium|||Sodium Glycocholate;Glycocholate Sodium|||S
Glycocholic Acid Sodium Salt (Sodium Glycocholate) is a conjugated bile salt and ionic biologic detergent. It is involved in the emulsification of fats.
价 格:¥电议型 号:T4070产 地:中国大陆
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T40407Histone H3 (5-23);Histone H3 (5-23)Histone H3 (5-23);Histone H3 (5-23)
Histone H3 (5-23), a derivative of histone H3 consisting of amino acids 5-23, serves as a substrate for histone acetyltransferase (HAT) assays.
价 格:¥电议型 号:T40407产 地:中国大陆
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T39407Azido-PEG8-C-Boc;Azido-PEG8-C-BocAzido-PEG8-C-Boc;Azido-PEG8-C-Boc
Azido-PEG8-C-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39407产 地:中国大陆
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T38407RTIL 13;RTIL 13RTIL 13
RTIL 13 is a highly effective inhibitor of dynamin GTPase, exhibiting an IC50 value of 2.3 μM for dynamin I GTPase. Furthermore, it selectively interacts with the pleckstrin homology lipid binding domain. This compound effectively suppresses both receptor-mediated and synaptic vesicle endocytosis, demonstrating IC50 values of 9.3 μM and 7.1 μM, respectively.
价 格:¥电议型 号:T38407产 地:中国大陆
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T37407Arachidonoyl-L-carnitine (chloride);Arachidonoyl-L-carnitine (chloride)C20:4 Carnitine?|||Arachidono
Carnitine facilitates the transport of fatty acids into the mitochondria to be used in fatty acid metabolism. It does so by accepting acyl groups from fatty acids complexed with coenzyme A, which yields esterified carnitine or acylcarnitines that enable the transport of fatty acyl groups into the inner mitochondrial matrix. β-Oxidation of fatty acids in mitochondria is inhibited by uncoupling conditions, thus changes in circulating levels of various acylcarnitines have been used to identify alte
价 格:¥电议型 号:T37407产 地:中国大陆
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T36407Pyrrolidine Ricinoleamide;Pyrrolidine RicinoleamidePyrrolidine Ricinoleamide
Ricinoleic acid is a naturally occurring 12-hydroxy fatty acid. It constitutes about 90% of the fatty acids in castor oil. Pyrrolidine Ricinoleamide is a derivative of the amide of ricinoleic acid that shows potent antiproliferative activity against an array of cancer cell lines, including human glioma U251 cells.
价 格:¥电议型 号:T36407产 地:中国大陆
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T35688MTIC;替莫唑胺代谢物- MTICNSC 407347;NSC 407347
MTIC is the active metabolite of Temozolomide (TMZ) with anticancer and antitumor activity and is used in the study of melanoma.3´-Sialyllactose (3´-SL) sodium is a prebiotic with anti-inflammatory activity.
价 格:¥电议型 号:T35688产 地:中国大陆
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T35407Ζ-Stat;化合物Ζ-StatΖ-Stat
ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis in melanoma cell lines, exhibiting antitumor activity in vitro[1][2].
价 格:¥电议型 号:T35407产 地:中国大陆
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T34729SU 14074;化合物 T34729SU-14074|||SU14074;SU-14074|||SU14074
SU 14074 is a bioactive chemical.
价 格:¥电议型 号:T34729产 地:中国大陆
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T34407RS 100235;化合物 T34407RS100235|||RS-100235;RS100235|||RS-100235
RS 100235 is a 5-HT4 Serotonin Receptor.
价 格:¥电议型 号:T34407产 地:中国大陆