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T64355TDI-10229CompoundTDI10229
TDI-10229 is a potent and orally available inhibitor of soluble adenylyl cyclase (sAC, ADCY10). TDI-10229 displays nanomolar inhibition of sAC in both biochemical and cellular assays (IC50= 195 nM). TDI-10229 exhibits mouse pharmacokinetic properties sufficient to warrant its use as an in vivo tool compound.
价 格：￥电议型 号：T64355产 地：中国大陆
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T6420BMS-707035BMS 707035,HIV-1 integrase strand transfer,HIV,Human immunodeficiency virus,antiviral,BMS7
BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.
价 格：￥电议型 号：T6420产 地：中国大陆
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T61864Melengestrol acetate
Melengestrol acetate is a derivative of progesterone and acts as a corticosteroid hormone. Melengestrol acetate promotes endometrial proliferation delay of menstrual activity and pregnancy maintenance.
价 格：￥电议型 号：T61864产 地：中国大陆
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T6423BRL-15572 dihydrochlorideh5-HT1D,BRL 15572 dihydrochloride,BRL15572,BRL 15572,5-HT Receptor,BRL-1557
BRL-15572 is a 5-HT1D receptor antagonist with pKi of 7.9, also shows a considerable affinity at 5-HT1A and 5-HT2B receptors, exhibiting 60-fold selectivity over 5-HT1B receptor.
价 格：￥电议型 号：T6423产 地：中国大陆
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T6964ResiquimodHepatitis C virus,R-848,S-28463,R 848,S 28463,Toll-like Receptor (TLR),Inhibitor,Resiquimo
Resiquimod is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and activating TLR7 and 8 mainly on dendritic cells, macrophages, and B-lymphocytes. This induces the nuclear translocation of the transcription activator NF-kB as well as activation of other transcription factors. This may lead to an increase in mRNA levels and subsequent production of cytokin
价 格：￥电议型 号：T6964产 地：中国大陆
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T6418BMS-378806BMS 378806,BMS 806,Human immunodeficiency virus,inhibit,HIV,BMS-378806,BMS806,Inhibitor
BMS-378806 selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.
价 格：￥电议型 号：T6418产 地：中国大陆
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T6403Siponimodinflammation,BAF312,Lysophospholipid Receptor,S1P receptor,inhibit,neurodegeneration,S1P1 a
BAF312 (Siponimod), a next-generation S1P receptor modulator, is specific for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, respectively. The specificity of BAF312 for S1P1 and S1P5 receptors exhibits >1000-fold over S1P2, S1P3 and S1P4 receptors.
价 格：￥电议型 号：T6403产 地：中国大陆
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T9647GX 201
GX 201 is a selective NaV1.7 inhibitor, IC50 of < 3.2 nM for hNaV1.7.
价 格：￥电议型 号：T9647产 地：中国大陆
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T64381BMF-219
BMF-219 is a specific irreversible inhibitor of Menin-MLL interactions. BMF-219 can be used in the study of alloimmune diseases, autoimmune diseases, cancer and other diseases dependent on menin-MLL.
价 格：￥电议型 号：T64381产 地：中国大陆
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T6564Leupeptin Hemisulfateinhibit,Cathepsin,Leupeptin Hemisulfate,Inhibitor
Leupeptin hemisulfate is a reversible, competitive serine/cysteine protease inhibitor. It is an orally active, antioxidant and anti-inflammatory agent.
价 格：￥电议型 号：T6564产 地：中国大陆
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T6649(S)-(+)-RolipramTNFα,tumor,inhibit,(S)(+)Rolipram,mononuclear,Apoptosis,phosphodiesterase,(S) (+) Ro
S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.
价 格：￥电议型 号：T6649产 地：中国大陆
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T64317ZZL-7ZZL7
ZZL-7 is a fast-onset antidepressant agent. ZZL-7 disrupts the interaction between the neuronal nitric oxide synthase (nNOS) and serotonin transporter (SERT) in the dorsal raphe nucleus (DRN). ZZL-7 can easily cross the blood-brain barrier readily. ZZL-7 has research value in major depressive disorder (MDD).
价 格：￥电议型 号：T64317产 地：中国大陆
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T6492Davercininhibit,Bacterial,Inhibitor,Antibiotic,Davercin
Erythromycin Cyclocarbonate, a derivative of Erythromycin, is active against Gram-positive and some Gram-negative microorganisms.
价 格：￥电议型 号：T6492产 地：中国大陆
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T9642ZW4864 free baseZW4864 free base
ZW4864 free base is an orally active and selective inhibitor of β catenin/B-Cell lymphoma 9 protein?protein interaction (β catenin/BCL9 PPI, Ki= 0.76 μM, IC50= 0.87 μM).
价 格：￥电议型 号：T9642产 地：中国大陆
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T6483EHT 1864EHT 1864,precursor,β-amyloid,protein,disease,Alzheimer,amyloid,EHT-1864,EHT1864,Ras,inhibit,
EHT 1864 is a effective Rac family GTPase inhibitor for Rac1/Rac1b/Rac2/Rac3 (Kd: 40/50/60/250 nM).
价 格：￥电议型 号：T6483产 地：中国大陆
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T8705BOT-64IL-6,BOT64,I kappa B kinase,inhibit,inflammatory,BOT-64,NF-κb,RAW 264.7,IKK,IκB kinase,Inhibit
BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase´s activation loop domain.BOT-64 is a cell-permeable benzoxathiole compound
价 格：￥电议型 号：T8705产 地：中国大陆
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T64366WAY-606956WAY606956
WAY-606956 is a GSK-3 inhibitor with IC50 of 0.101-1 μM of GSK-3α and GSK-3β in Calipe Assay.
价 格：￥电议型 号：T64366产 地：中国大陆
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T6664SecinH3SecinH 3,Apoptosis,inhibit,SecinH-3,SecinH3,Inhibitor
SecinH3 is selective cytohesin inhibitor.
价 格：￥电议型 号：T6664产 地：中国大陆
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T8564BC-1382interaction,Anti-inflammatory,ligase,Inhibitor,lung,Ubiquitin,E1 activating enzyme,Ubiquitin
BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction(IC50 of 5 nM).
价 格：￥电议型 号：T8564产 地：中国大陆
