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T6420BMS-707035化合物BMS707035N-[(4-氟苯基)甲基1,6-二氢-5-羟基-1-甲基-6-氧代-2-(四氢-1,1-二氧-2H-1,2-噻嗪-2-基)-4-嘧啶甲酰胺
BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.
价 格:¥电议型 号:T6420产 地:中国大陆
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T63642CQ211;化合物CQ211CQ211
CQ211 is a potent and selective RIOK2 inhibitor with a Kd of 6.1 nM.CQ211 has shown potent proliferation inhibitory activity against various cancer cell lines in vitro.
价 格:¥电议型 号:T63642产 地:中国大陆
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T62642Microtubule inhibitor 4;化合物 Microtubule inhibitor 4Microtubule inhibitor 4
Microtubule inhibitor 4 (compound 2) is a potent inhibitor of microtubule and inhibits microtubule protein polymerization, HT-29 cells (IC50: 2.1 nM) exhibited cytotoxicity.
价 格:¥电议型 号:T62642产 地:中国大陆
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T62053Lorpucitinib;化合物LorpucitinibJNJ-64251330;JNJ-64251330
Lorpucitinib (JNJ-64251330) is an orally available, selective and potent JAK kinase inhibitor for the study of inflammatory and gastrointestinal disorders associated with Janus kinase (JAK) signaling.
价 格:¥电议型 号:T62053产 地:中国大陆
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T61642CCW16;化合物 CCW16CCW16
CCW16 is a covalent ligand specifically designed for the E3 ubiquitin ligase RNF4. It serves as a valuable tool in the creation of protein degraders, facilitating the exploration of targeted protein degradation. [1]
价 格:¥电议型 号:T61642产 地:中国大陆
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T6108Ki16425;化合物Ki16425Debio 0719;Debio 0719
Ki16425 (Debio 0719) is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively.
价 格:¥电议型 号:T6108产 地:中国大陆
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T60642SN40;化合物 SN40SN40
SN40 is a potent amino acid transport (AAT) inhibitor that can be used in anticancer research. SN40 has Kis of 7.29 μM, 2.42 μM, 2.94 μM, 5.55 μM, 24.43 μM and 5.55 μM for human ASCT1, rat ASCT2, human ASCT2, EAAT1, EAAT2, EAAC1 and EAAT5, respectively [1].
价 格:¥电议型 号:T60642产 地:中国大陆
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T5642Tegatrabetan;化合物BC2059BC2059;BC2059
Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.
价 格:¥电议型 号:T5642产 地:中国大陆
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T500642-(4-methoxyphenyl)-2-oxoethyl 2-hydroxy-5-methylbenzoate;化合物T500642-(4-methoxyphenyl)-2-oxoethyl 2-
2-(4-methoxyphenyl)-2-oxoethyl 2-hydroxy-5-methylbenzoate is a pro-neurotropic drug used to enhance cognitive function by increasing the synthesis and release of acetylcholine in the brain as well as by inhibiting the breakdown of acetylcholine by acetylcholinesterase.
价 格:¥电议型 号:T50064产 地:中国大陆
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T4642Tenovin-2;化合物Tenovin-2Tenovin-2
Tenovin-2 has a wide range of applications in life science related research.
价 格:¥电议型 号:T4642产 地:中国大陆
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T4313Tinoridine hydrochloride;盐酸替诺立定Nonflamin|||Y-3642 hydrochloride;盐酸替诺立定|||Nonflamin|||Y-3642 hydrochl
Tinoridine hydrochloride (Y-3642 hydrochloride) is a non-steroidal anti-inflammatory drug. Tinoridine hydrochloride (5-100 μM), produced a concentration-dependent inhibition on the simultaneous increases in lipid peroxide formation and renin release induced by 50 μM ascorbic acid in the renin granule fraction. On the other hand, indomethacin, hydrocortisone, and prednisolone, which had no ability to inhibit the lipid peroxidation in the renin granule fraction, did not influence the release of re
价 格:¥电议型 号:T4313产 地:中国大陆
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T4166UNC0642;化合物UNC0642UNC-0642|||UNC 0642;UNC-0642|||UNC 0642
UNC0642 is an effective and specific G9a/GLP inhibitor (IC50< 2.5 nM).
价 格:¥电议型 号:T4166产 地:中国大陆
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T40642Chlorpyrifos-oxon;Chlorpyrifos-oxonChlorpyrifos-oxon
Chlorpyrifos-oxon, an active metabolite of Chlorpyrifos, is a powerful phosphorylating agent with potent inhibition of AChE activity. It induces cross-linking between tubulin subunits and disrupts microtubule function[4].
价 格:¥电议型 号:T40642产 地:中国大陆
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T39248PF-06426779;PF-06426779PF-06426779
PF-06426779 is a potent and selective inhibitor of interleukin 1 receptor associated kinase 4 (IRAK4) , with an IC 50 of 0.3 nM.
价 格:¥电议型 号:T39248产 地:中国大陆
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T39148FR179642;FR179642FR179642|||FR179642|||FR 179642|||FR179642|||FR-179642|||FR-179642;FR179642|||FR179
FR179642 is an essential intermediate compound utilized in the synthesis of Micafungin, an antifungal drug belonging to the echinocandin class. It serves as the cyclic peptide foundation for the structurally similar antifungal lipopeptide FR901379.
价 格:¥电议型 号:T39148产 地:中国大陆
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T37642Pravastatin lactone;Pravastatin lactonePravastatin lactone
Pravastatin lactone is a metabolite of pravastatin , a hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor that is a ring-hydroxylated metabolite of mevastatin . Pravastatin lactone is formed when pravastatin undergoes acid-catalyzed non-enzymatic lactonization in the stomach following oral administration.
价 格:¥电议型 号:T37642产 地:中国大陆
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T36642RAS/RAS-RAF-IN-1;RAS/RAS-RAF-IN-1RAS/RAS-RAF-IN-1
RAS/RAS-RAF-IN-1 is a potent RAS and RAS-RAF inhibitor. RAS/RAS-RAF-IN-1 has a KD of 5.0 μμ-15 μμ for cyclophilin A (CYPA) binding affinity. RAS/RAS-RAF-IN-1 has antitumor activity[1].
价 格:¥电议型 号:T36642产 地:中国大陆
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T36442L(Hyp?)-Bradykinin acetate;化合物(Hyp?)-Bradykinin acetate(Hyp?)-Bradykinin acetate (37642-65-2 Free bas
(Hyp?)-Bradykinin acetate is an agonist of bradykinin B2 receptor and stimulates inositol phosphate production in cultured human fibroblasts.
价 格:¥电议型 号:T36442L产 地:中国大陆
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T36428PACAP-related Peptide (human) (trifluoroacetate salt);PACAP-related Peptide (human) (trifluoroacetat
PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin , glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adenylate cyclase-activating polypeptide . It is expressed in normal human pancreas and adrenal gland tissue and in some tumors that produce vasoactive intestinal peptide (VIP). PRP (1-29) is secreted by CHO-K1 cells that express human recombinant preproPACAP.
价 格:¥电议型 号:T36428产 地:中国大陆
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T36427PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt);PACAP (6-27) (huma
Pituitary adenylate cyclase-activating peptide (PACAP) (6-27) is a PACAP receptor antagonist with IC50 values of 1,500, 600, and 300 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expressed in CHO cells. It binds to PACAP receptors on SH-SY5Y and SK-N-MC human neuroblastoma and T47D human breast cancer cells (IC50s = 24.5, 106, and 105 nM, respectively) and inhibits cAMP accumulation induced by PACAP (1-38) (Kis = 457, 102, and 283 nM, respectively, in SH-SY5Y,
价 格:¥电议型 号:T36427产 地:中国大陆