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T61156L-Lysyl-L-lysine dihydrochloride
L-Lysyl-L-lysine dihydrochloride is an enzyme cleavable linker. L-Lysyl-L-lysine dihydrochloride can be used as facile linker for delivering multiple biologically active peptides.
价 格:¥电议型 号:T61156产 地:中国大陆
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T8758Poziotinib hydrochloridePoziotinib hydrochloride
Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. It is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.
价 格:¥电议型 号:T8758产 地:中国大陆
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T8565N4-benzyl-N2-methylquinazoline-2,4-diamine hydrochlorideN4 benzyl N2 methylquinazoline 2,4 diamine h
N4-benzyl-N2-methylquinazoline-2,4-diamine hydrochloride is an inhibitor of TRPC4.
价 格:¥电议型 号:T8565产 地:中国大陆
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T7742GW 284543 hydrochlorideGW 284543 hydrochloride
GW 284543 hydrochloride is a selective inhibitor of MEK5 .
价 格:¥电议型 号:T7742产 地:中国大陆
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T19337GBR 12783 dihydrochloride
GBR 12783 dihydrochloride is a specific, potent and selective dopamine uptake inhibitor. GBR 12783 dihydrochloride inhibits the [3H]dopamine uptake by rat and mice striatal synaptosomes with IC50s of 1.8 nM and 1.2 nM, respectively.GBR 12783 dihydrochloride can improve memory performance and increase hippocampal acetylcholine release in rats.
价 格:¥电议型 号:T19337产 地:中国大陆
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T6592ML133 hydrochloridePotassium Channel,KcsA,Inhibitor,inhibit,ML 133,ML-133 hydrochloride,ML133 hydroc
ML133 HCl is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.
价 格:¥电议型 号:T6592产 地:中国大陆
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T7002Trihexyphenidyl hydrochloridemAChR,inhibit,dystonia,Inhibitor,Trihexyphenidyl,Muscarinic acetylcholi
Trihexyphenidyl hydrochloride is an antiparkinsonian agent of the antimuscarinic class.
价 格:¥电议型 号:T7002产 地:中国大陆
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T60047LV-0219 hydrochloride
V-0219 hydrochloride is an orally active, positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R). V-0219 hydrochloride can be used for obesity-associated diabetes research.
价 格:¥电议型 号:T60047L产 地:中国大陆
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T9543Syk Inhibitor II hydrochlorideSyk Inhibitor II hydrochloride
The impact of spleen tyrosine kinase (Syk) signaling might be prominent in lupus because (i) Syk is a shared downstream signaling molecule among circulating immune complex, LPS, and (1→3)-β-D-glucan (BG), and (ii) all of these factors are detectable in the serum of Fc gamma receptor IIb-deficient (FcgRIIb-/-) mice with sepsis. Syk inhibition downregulated several inflammatory pathways in FcgRIIb-/- macrophages activated with BG + LPS suggesting the potential anti-inflammatory impact of Syk inhib
价 格:¥电议型 号:T9543产 地:中国大陆
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T7746Eltoprazine dihydrochlorideEltoprazine dihydrochloride
Eltoprazine dihydrochloride is a drug that had previously been developed for aggression, has recently been investigated for L-DOPA-induced dyskinesia in animal models of Parkinson′s disease (PD) and in dyskinetic PD patients.
价 格:¥电议型 号:T7746产 地:中国大陆
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T6426Buclizine dihydrochlorideteratogen,Inhibitor,MCF-7,anti-tumor activity,antiallergic,antihistamine,in
Buclizine HCl is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities. Buclizine binds to and blocks the histamine H1 receptor, thereby preventing the symptoms that are caused by histamine activity. Buclizine exerts its anti-emetic effect by binding to and blocking the muscarinic and histamine receptors in the vomiting center of the central nervous system (CNS). This may prevent activation of the chemorecepto
价 格:¥电议型 号:T6426产 地:中国大陆
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T7488BD1063 dhydrochlorideSigma Receptor,Inhibitor,inhibit,BD1063 dhydrochloride,BD-1063 dhydrochloride
BD1063 is a potent and selective sigma 1(σ1) receptor antagonist(Ki = 9 nM).
价 格:¥电议型 号:T7488产 地:中国大陆
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T6441CGS 21680 HydrochlorideCGS-21680,Inhibitor,CGS 21680,inhibit,CGS21680,CGS 21680 Hydrochloride,Adenos
CGS 21680 HCl( IC50=22 nM), an adenosine receptor agonist, exhibits 140-fold potency in A2 receptor over A1 receptor.
价 格:¥电议型 号:T6441产 地:中国大陆
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T8543KN-92 hydrochlorideInhibitor,derivative,experimental,inactive,KN-92,KN92 hydrochloride,KN92,inhibit,
KN-92 hydrochloride is an inactive derivative of KN-93. KN-93 is a selective Ca2+/calmodulin-dependent kinase II (CaMKII) inhibitor, competitively blocking CaM binding to the kinase with Ki of 370 nM.
价 格:¥电议型 号:T8543产 地:中国大陆
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T7505Azimilide DihydrochlorideInhibitor,Azimilide,Azimilide Dihydrochloride,Potassium Channel,NE 10064,NE
Azimilide Dihydrochloride, a novel class III antiarrhythmic agent, blocks both the slowly activating (IKs) and rapidly activating (IKr) components of the delayed rectifier potassium current
价 格:¥电议型 号:T7505产 地:中国大陆
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T8004SNAP 94847 hydrochlorideAntidepressant,SNAP-94847,Melanin concentrating hormone receptor 1,anxiety,i
SNAP 94847 hydrochloride is a melanin-concentrating hormonereceptor1 (MCHR1) antagonist(Ki= 2.2 nM)
价 格:¥电议型 号:T8004产 地:中国大陆
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T10813Cilobradine hydrochloride
Cilobradine hydrochloride is an HCN Channel blocker and an open channel blocker of neuronal Ih and related cardiac If channels.
价 格:¥电议型 号:T10813产 地:中国大陆
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T7940Milnacipran ((1S-cis) hydrochloride)SERT,Milnacipran ((1S-cis) hydrochloride),F-2695,Milnacipran ((1
Milnacipran ((1S-cis) hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI), treatment of fibromyalgia.
价 格:¥电议型 号:T7940产 地:中国大陆
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T18640(S,R,S)-AHPC-C4-NH2 hydrochlorideinhibit,E3 Ligase Ligand-Linker Conjugates,(S,R,S)AHPCC4NH2 hydroch
(S,R,S)-AHPC-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker.
价 格:¥电议型 号:T18640产 地:中国大陆
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T21584CP 465022 hydrochlorideCP 465022 hydrochloride
CP 465022 hydrochloride is a potent, and selective noncompetitive antagonist of AMPA receptor with anticonvulsant activity. CP 465022 hydrochloride inhibits Kainate-induced response with an IC50 of 25 nM in rat cortical neurons.
价 格:¥电议型 号:T21584产 地:中国大陆