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T80062Mitogen-activated protein kinase 1;化合物 Mitogen-activated protein kinase 1MAPK1;MAPK1
Mitogen-activated protein kinase 1 (MAPK1) activates the p38/NF-κB pathway and regulates cellular processes in sepsis-associated diseases. Its catalytic action phosphorylates substrate proteins, serving as a regulatory switch for their activity [1].
价 格:¥电议型 号:T80062产 地:中国大陆
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T800375-FAM-β-Amyloid (1-28);化合物 5-FAM-β-Amyloid (1-28)5-FAM-Amyloid β-protein (1-28);5-FAM-Amyloid β-prot
5-FAM-β-Amyloid (1-28) is a fluorescently-labeled peptide corresponding to the first 28 amino acids of the β-Amyloid protein.
价 格:¥电议型 号:T80037产 地:中国大陆
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T79221RSV L-protein-IN-5;化合物 RSV L-protein-IN-5RSV L-protein-IN-5
RSV L-protein-IN-5 (Compound E) serves as a potent inhibitor of the Respiratory Syncytial Virus (RSV), with an EC50 value of 0.1 μM. It targets RSV polymerase with an IC50 of 0.66 μM and impedes RSV mRNA synthesis through the inhibition of transcript guanylation. The compound demonstrates moderate cytotoxicity, with a CC50 of 10.7 μM in HEp-2 cells, and effectively reduces viral titers in mouse models of RSV infection [1].
价 格:¥电议型 号:T79221产 地:中国大陆
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T79220RSV L-protein-IN-4;化合物 RSV L-protein-IN-4RSV L-protein-IN-4
RSV L-protein-IN-4 (Compound C) is a noncompetitive inhibitor of the RSV polymerase with an IC50 of 0.88 μM. It demonstrates potent antiviral activity against RSV strains, with an EC50 of 0.25 μM [1].
价 格:¥电议型 号:T79220产 地:中国大陆
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T79219RSV L-protein-IN-3;化合物 RSV L-protein-IN-3RSV L-protein-IN-3
RSV L-protein-IN-3 is an inhibitor of the wild-type RSV polymerase, exhibiting an IC50 of 10.4 μM and an EC50 of 2.1 μM (against RSV), and possesses lower cytotoxicity compared to the clinical agent Ribavirin [1].
价 格:¥电议型 号:T79219产 地:中国大陆
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T79217RSV L-protein-IN-2;化合物 RSV L-protein-IN-2RSV L-protein-IN-2
RSV L-protein-IN-2 (Compound A), a noncompetitive inhibitor of the RSV polymerase (IC50: 4.5 μM), exhibits antiviral activity against long RSV strains (EC50: 1.3 μM) [1].
价 格:¥电议型 号:T79217产 地:中国大陆
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T79126Protein kinase inhibitor 5 sulfate hydrate;化合物 Protein kinase inhibitor 5 sulfate hydrateProtein kin
Protein kinase inhibitor 5 sulfate hydrate, a potent TRK-A inhibitor, exhibits an IC50 of 1.8 nM and impairs cell viability [1].
价 格:¥电议型 号:T79126产 地:中国大陆
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T79125Protein kinase inhibitor 5;化合物 Protein kinase inhibitor 5Protein kinase inhibitor 5
Protein kinase inhibitor 5 is a potent inhibitor of TRK-A, demonstrating an IC50 of 1.8 nM, and effectively suppresses cell viability [1].
价 格:¥电议型 号:T79125产 地:中国大陆
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T79038Tau protein aggregation-IN-1;化合物 Tau protein aggregation-IN-1Tau protein aggregation-IN-1
Tau Protein Aggregation-IN-1 (Compound 0c) serves as an inhibitor of Tau protein aggregation, applicable in research related to protein folding disorders including Alzheimer´s disease, dementia, Parkinson´s disease, Huntington´s disease, and prion-based spongiform encephalopathies [1].
价 格:¥电议型 号:T79038产 地:中国大陆
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T7885Afuresertib hydrochloride化合物Afuresertib hydrochlorideAfuresertib|||PKC|||Protein kinase C
Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)
价 格:¥电议型 号:T7885产 地:中国大陆
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T78370Myelin Basic Protein(87-99) TFA;化合物 Myelin Basic Protein(87-99) TFAMyelin Basic Protein(87-99) TFA
Myelin Basic Protein(87-99) TFA, an encephalitogenic peptide, promotes basic protein-specific T cell proliferation and induces Th1 polarization in peripheral blood mononuclear cells, which is associated with the pathogenesis of multiple sclerosis (MS) [1] [2].
价 格:¥电议型 号:T78370产 地:中国大陆
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T78365Endoproteinase Lys-C;化合物 Endoproteinase Lys-CEndoproteinase Lys-C
Endoproteinase Lys-C, commonly utilized for protein sequencing [1], is a protease that specifically cleaves proteins on the C-terminal side of lysine residues.
价 格:¥电议型 号:T78365产 地:中国大陆
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T78298Alefacept;化合物 AlefaceptLFA 3TIP|||Human LFA 3IgG fusion protein|||BG 9273;LFA 3TIP|||Human LFA 3IgG
Alefacept (BG 9273), a fusion protein combining human lymphocyte function-associated antigen 3 with immunoglobulin 1, is utilized in the research of chronic plaque psoriasis [1].
价 格:¥电议型 号:T78298产 地:中国大陆
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T77805KRAS G12C mutant protein inhibitor A-1;化合物 KRAS G12C mutant protein inhibitor A-1KRAS G12C mutant pr
KRAS G12C mutant protein inhibitor A-1 can be used in studies about Ras.
价 格:¥电议型 号:T77805产 地:中国大陆
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T76663pTH-Related Protein (1-40) (human, mouse, rat);化合物 pTH-Related Protein (1-40) (human, mouse, rat)pTH
pTH-Related Protein (1-40) (human, mouse, rat) enhances calcium absorption in rat intestinal cells by activating the PTHR1 receptor and the PKCα/β signaling pathways. This compound also increases the expression of the parathyroid hormone 1 receptor (PTHR1) and four key proteins involved in transcellular calcium transport: potential vanillin member 6 (TRPV6), calcium-binding protein-D9K (CaBP-D9k), sodium-calcium Exchanger 1 (NCX1), and plasma membrane calcium ATPase 1 (PMCA1) [1].
价 格:¥电议型 号:T76663产 地:中国大陆
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T76647Acetyl-Amyloid β-Protein (1-6) amide;化合物 Acetyl-Amyloid β-Protein (1-6) amideAcetyl-Amyloid β-Protei
Acetyl-Amyloid β-Protein (1-6) amide, a hexapeptide with a potential copper(II) binding site, is utilized in research focused on Alzheimer´s disease and related disorders [1].
价 格:¥电议型 号:T76647产 地:中国大陆
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T76636(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat);化合物 (Tyr36)-pTH-Related Protein (1-36) (human
´(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat), a peptide, functions as a ligand for parathyroid hormone (PTH) receptors [1].´
价 格:¥电议型 号:T76636产 地:中国大陆
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T76625(Lys22)-Amyloid β-Protein (1-42);化合物 (Lys22)-Amyloid β-Protein (1-42)(Lys22)-Amyloid β-Protein (1-42
´(Lys22)-Amyloid β-Protein (1-42) represents a mutation of the wild-type (WT) Amyloid β-Protein (1-42) peptide [1].´
价 格:¥电议型 号:T76625产 地:中国大陆
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T76623(Gln22)-Amyloid β-Protein (1-42);化合物 (Gln22)-Amyloid β-Protein (1-42)(Gln22)-Amyloid β-Protein (1-42
(Gln22)-Amyloid β-Protein (1-42), a Dutch mutation (E22Q) variant of β-Amyloid (1-42), demonstrates increased fibrillogenic and pathogenic characteristics [1].
价 格:¥电议型 号:T76623产 地:中国大陆
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T76588(Asp37)-Amyloid β-Protein (1-42);化合物 (Asp37)-Amyloid β-Protein (1-42)(Asp37)-Amyloid β-Protein (1-42
´(Asp37)-Amyloid β-Protein (1-42) [1]´ refers to the G37D mutant variant of the wild-type Amyloid-beta (1-42) peptide.
价 格:¥电议型 号:T76588产 地:中国大陆