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  • T39969TLR7/8 agonist 4 TFA；TLR7/8 agonist 4 TFATLR7/8 agonist 4 TFA

    TLR7/8 agonist 4 TFA (compound 41) is a highly potent TLR7/8 agonist that exhibits significant anti-cancer activity.

    价 格：￥电议型 号：T39969产 地：中国大陆

  • T39968TLR7/8 agonist 4 hydroxy-PEG10-acid；TLR7/8 agonist 4 hydroxy-PEG10-acidTLR7/8 agonist 4 hydroxy-PEG1

    TLR7/8 agonist 4 hydroxy-PEG10-acid (compound 9) is a drug-linker conjugate employed in antibody-drug conjugates (ADC). This compound exhibits remarkable antitumor activity by utilizing TLR7/8 agonist 4, which acts as a potent activator of TLR7/8. The TLR7/8 agonist 4 is linked to hydroxy-PEG10-acid, the ADC linker, via a cleavable bond. Overall, it demonstrates promising pharmaceutical potential in the context of ADC-based therapeutics.

    价 格：￥电议型 号：T39968产 地：中国大陆

  • T39669TLR7/8/9-IN-1；TLR7/8/9-IN-1TLR7/8/9-IN-1；TLR7/8/9-IN-1

    TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM.

    价 格：￥电议型 号：T39669产 地：中国大陆

  • T39522HTL22562；HTL22562HTL22562

    HTL22562 is a calcitonin gene-related peptide (CGRP) receptor antagonist for acute treatment of migraine.

    价 格：￥电议型 号：T39522产 地：中国大陆

  • T39258PulrodemstatPulrodemstatLSD1-IN-7|||CC-90011

    Pulrodemstat (CC-90011) is a highly potent and selective inhibitor of lysine specific demethylase-1 (LSD1). It exhibits a reversible mode of action and can be administered orally. With an impressive IC50 of 0.25 nM, Pulrodemstat effectively suppresses the enzymatic activity of LSD1. Notably, it demonstrates minimal inhibition against LSD2, MOA-A, and MAO-B enzymes. Moreover, Pulrodemstat possesses remarkable anticancer properties, promoting differentiation in acute myeloid leukemia (AML) and sma

    价 格：￥电议型 号：T39258产 地：中国大陆

  • T39191LDSTYSLSSTLTLSK acetate；化合物DSTYSLSSTLTLSK acetateDSTYSLSSTLTLSK acetate (177792-42-6 Free base)；DSTYS

    DSTYSLSSTLTLSK acetate is a human generic peptide that can be used for the quantitative detection of infliximab.

    价 格：￥电议型 号：T39191L产 地：中国大陆

  • T39191DSTYSLSSTLTLSK；DSTYSLSSTLTLSKDSTYSLSSTLTLSK

    DSTYSLSSTLTLSK, a human peptide, facilitates the quantitative detection of Infliximab (Avakine), a chimeric monoclonal IgG1 antibody. Infliximab specifically targets and binds to TNF-α.

    价 格：￥电议型 号：T39191产 地：中国大陆

  • T39103Pafolacianine；PafolacianineOTL 38；OTL 38

    Pafolacianine (OTL 38) is a near-infrared dye-based fluorescent marker utilized for identifying ovarian cancer lesions during surgeries.

    价 格：￥电议型 号：T39103产 地：中国大陆

  • T39014KSPWFTTL；KSPWFTTLKSPWFTTL

    KSPWFTTL is an immunodominant epitope derived from the p15E transmembrane protein. It is Kb-restricted and can enhance the susceptibility of a tumor cell line to cytotoxic T lymphocytes targeting anti-AKR/Gross MuLV.

    价 格：￥电议型 号：T39014产 地：中国大陆

  • T38614TLR7 agonist 3；TLR7 agonist 3TLR7 agonist 3

    TLR7 agonist 3 (Compound 2), a potent activator of toll-like receptor 7 (TLR7), plays a critical role in initiating immune responses, positioning it as a promising target for immunomodulator development.

    价 格：￥电议型 号：T38614产 地：中国大陆

  • T38547TLR4-IN-C34-C2-COOH；TLR4-IN-C34-C2-COOHTLR4-IN-C34-C2-COOH；TLR4-IN-C34-C2-COOH

    TLR4-IN-C34-C2-COO is a linker compound that incorporates TLR4 inhibitor TLR4-IN-C34. It effectively inhibits TLR4 activity in enterocytes and macrophages. Moreover, it demonstrates a notable ability to mitigate systemic inflammation in murine models of endotoxemia and necrotizing enterocolitis.

    价 格：￥电议型 号：T38547产 地：中国大陆

  • T38377ADTL-EI1712；ADTL-EI1712ADTL-EI1712；ADTL-EI1712

    ADTL-EI1712 is a dual inhibitor of ERK1 and ERK5 (IC50s = 40.43 and 64.5 nM, respectively).1It reduces ERK1 and ERK5 activity by 93.5% and 89.4%, respectively, but also inhibits ERK2 activity by 92.7%, in a panel of 100 kinases at 1 μM. ADTL-EI1712 inhibits proliferation of HL-60 and MKN74, but not HeLa, cancer cells (IC50s = 1.26, 2.55, and >50 μM, respectively). It reduces tumor growth and intratumor phosphorylation of ERK1/2 and ERK5 in an MKN74 mouse xenograft model when administered at a do

    价 格：￥电议型 号：T38377产 地：中国大陆

  • T38169LY 341495 disodium salt；LY 341495 disodium saltLY 341495 disodium salt

    Highly potent and selective group II metabotropic glutamate receptor antagonist. Disodium salt of LY 341495

    价 格：￥电议型 号：T38169产 地：中国大陆

  • T38078TLR7/8-IN-1；化合物TLR7/8-IN-1TLR7/8-IN-1；TLR7/8-IN-1

    TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor, is a valuable compound for autoimmune disease research[1].

    价 格：￥电议型 号：T38078产 地：中国大陆

  • T38077TLQP-21 TFA；TLQP-21 TFATLQP-21 TFA

    TLQP-21 TFA, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor1 (C3aR1) agonist (EC50: mouse TLQP-21=10.3 μM; human TLQP-21=68.8μM). TLQP-21 TFA activates C3aR1 to induce an increase of intracellular Ca2+. TLQP-21 TFA is used for the research in regulation of nociception and other relevant physiologic functions[1][2].

    价 格：￥电议型 号：T38077产 地：中国大陆

  • T37695NMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQ；NMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNMNNAGDKWSAFLKE

    NMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQ, an ACE2-related peptide, serves as a valuable research tool for comprehending ACE2 functions.

    价 格：￥电议型 号：T37695产 地：中国大陆

  • T37084TL13-22；TL 13-22TL 13-22；TL 13-22

    Negative control for TL 13-12 . Displays no degradation of ALK in cell lines. Highly potent inhibitor of ALK (IC50 = 0.54 nM)

    价 格：￥电议型 号：T37084产 地：中国大陆

  • T37083TL13-110；TL 13-110TL 13-110；TL 13-110

    Negative control for TL 13-112 . Displays no degradation of ALK in cell lines. Highly potent ALK inhibitor (IC50 = 0.34 nM).

    价 格：￥电议型 号：T37083产 地：中国大陆

  • T36816S-trityl-L-Cysteine；S-三苯甲基-L-半胱氨酸STLC；STLC

    S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5

    价 格：￥电议型 号：T36816产 地：中国大陆

  • T3633Crenigacestat；化合物CrenigacestatLY3039478；LY3039478

    Crenigacestat (LY3039478) is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in most of the tumor cell lines tested. Crenigacestat effectively inhibits mutant Notch receptor activity. In a xenograft tumor model, Crenigacestat inhibited expression of Notch-regulated genes and N1ICD cleavage in the tumor microenvironment.

    价 格：￥电议型 号：T3633产 地：中国大陆

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