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T62453Orexin receptor antagonist 3;化合物 Orexin receptor antagonist 3Orexin receptor antagonist 3
Orexin receptor antagonist 3 (example 216) is an orexin receptor antagonist.
价 格:¥电议型 号:T62453产 地:中国大陆
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T62420P2Y2R/GPR17 antagonist 1;P2Y2R/GPR17拮抗剂1P2Y2R/GPR17 antagonist 1
P2Y2R/GPR17 antagonist 1 (Compound 14m) is a dual P2Y2R (IC50: 3.17 μM) and GPR17 (IC50: 1.67 μM) antagonist.
价 格:¥电议型 号:T62420产 地:中国大陆
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T62348A1AR antagonist 3;化合物 A1AR antagonist 3A1AR antagonist 3
A1AR antagonist 3 (compound 13) is a selective adenylate 1 (A1) receptor antagonist that acts on human A1 (Ki: 9.69 nM) and rat A1 (Ki: 0.529 nM). A1AR antagonist 3 can be used to study neurological diseases.
价 格:¥电议型 号:T62348产 地:中国大陆
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T62325CXCR7 antagonist-1 hydrochloride;化合物 CXCR7 antagonist-1 hydrochlorideCXCR7 antagonist-1 hydrochlorid
CXCR7 antagonist-1 hydrochloride is a CXCR7 antagonist that inhibits the binding of SDF-1 chemokine (also known as CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. hydrochloride can be used for the prevention of tumour cell proliferation, tumour formation, inflammatory diseases and many other diseases.
价 格:¥电议型 号:T62325产 地:中国大陆
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T62311Estrogen receptor β antagonist 2;化合物 Estrogen receptor β antagonist 2Estrogen receptor β antagonist
Estrogen receptor β antagonist 2 is a selective, potent estrogen receptor β (ERβ) antagonist that acts on Erα (IC50: 109.10 μM) and Erβ (IC50: 0.63 μM).
价 格:¥电议型 号:T62311产 地:中国大陆
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T62261GPR84 antagonist 1;化合物 GPR84 antagonist 1GPR84 antagonist 1
GPR84 antagonist 1 is a highly selective, high-affinity competitive antagonist of human GPR84.
价 格:¥电议型 号:T62261产 地:中国大陆
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T62250GPVI antagonist 2;化合物 GPVI antagonist 2GPVI antagonist 2
GPVI antagonist 2 (Compound 1) is a potential Glycoprotein VI (GPVI) antagonist, able to act on collagen (IC50: 0.35 μM), CRP (IC50: 0.80 μM), convulxin (IC50: 195.2 μM), thrombin (IC50. 81.38 μM). GPVI antagonist 2 is a promising anti-platelet agent.
价 格:¥电议型 号:T62250产 地:中国大陆
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T62178TLR7/8 antagonist 1;化合物 TLR7/8 antagonist 1TLR7/8 antagonist 1
TLR7/8 Antagonist 1 (Compound 16c), an imidazoquinoline derivative, is a potent TLR7/8 agonist with IC50 values of 3.91 and 2.19 μM for TLR7 and TLR8, respectively. rel-O-2050 (TLR-2050) is a key target for drug development in infectious diseases, cancer and autoimmune diseases.
价 格:¥电议型 号:T62178产 地:中国大陆
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T62134A1/A3 AR antagonist 1;化合物 A1/A3 AR antagonist 1A1/A3 AR antagonist 1
A1/A3 AR antagonist 1 (Compound 10) is a potent, dual adenosine 1 (A1) and adenosine 3 (A3) receptor antagonist that acts on human A1 (Ki: 37.6 nM), human A3 (Ki: 25.4 nM) and rat A1 (Ki: 1.47 nM). 1 Can be used to study renal failure, inflammatory lung disease and Alzheimer´s disease.
价 格:¥电议型 号:T62134产 地:中国大陆
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T62126(Rac)-NMDAR antagonist 1;化合物 (Rac)-NMDAR antagonist 1(Rac)-NMDAR antagonist 1
(Rac)-NMDAR antagonist 1 is a racemate of NMDAR antagonist 1. NMDAR antagonist 1 is a potent, orally active, NR2B-selective NMDAR antagonist.
价 格:¥电议型 号:T62126产 地:中国大陆
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T62050Orexin receptor antagonist 4;化合物 Orexin receptor antagonist 4Orexin receptor antagonist 4
Orexin receptor antagonist 4 is potent and selective orexin 2 receptor (OX2R) antagonist. Orexin receptor antagonist 4 shows IC50 of 4.27 nM and 295 nM for OX2R and OX1R, respectively.
价 格:¥电议型 号:T62050产 地:中国大陆
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T61989CB1R antagonist 1;CB1R拮抗剂1CB1R antagonist 1
CB1R antagonist 1 is a potent CB1R antagonist that can be used to study diseases related to the nervous system.
价 格:¥电议型 号:T61989产 地:中国大陆
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T61923ERRα antagonist-2;化合物 ERRα antagonist-2ERRα antagonist-2
ERRα antagonist-2 (Compound 11) is a potential Reverse agonist of ERR α (estrogen receptor related receptor α) (IC50=0.80 μ M). ERRα antagonist-2 can inhibit the migration and invasion of ER-negative MDA-MB-231 cells. ERRα antiagonist-2 inhibits the growth of breast cancer in vivo.
价 格:¥电议型 号:T61923产 地:中国大陆
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T61909Estrogen receptor antagonist 7;化合物 Estrogen receptor antagonist 7Estrogen receptor antagonist 7
Estrogen Receptor Antagonist 7 (Compound 13) is a potent antagonist of estrogen receptors (ER), demonstrating antiproliferative effects against breast and ovarian cancer cells, along with anticancer and anti-uterotrophic activities [1].
价 格:¥电议型 号:T61909产 地:中国大陆
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T618375-HT6/5-HT2AR antagonist-1;化合物 5-HT6/5-HT2AR antagonist-15-HT6/5-HT2AR antagonist-1
5-HT6/5-HT2AR antagonist-1 is a powerful and effective compound that acts as a dual antagonist for both the 5-HT6 and 5-HT2A receptors. It exhibits high potency with K i values of 11 nM and 39 nM for the respective receptors [1].
价 格:¥电议型 号:T61837产 地:中国大陆
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T61813AMPA receptor antagonist-3;AMPA受体拮抗剂3AMPA receptor antagonist-3
AMPA receptor antagonist-3 is an AMPA receptor antagonist.
价 格:¥电议型 号:T61813产 地:中国大陆
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T61811GPVI antagonist 3;化合物 GPVI antagonist 3GPVI antagonist 3
GPVI antagonist 3 (Compound 2) is a potential antagonist that shows promising antiplatelet activity by selectively inhibiting the interaction between the Glycoprotein VI (GPVI) receptor and its ligands. It demonstrates potent inhibitory effects, with IC50 values of 1.01 μM for collagen, 1.92 μM for CRP, 7.24 μM for convulxin, and 51.74 μM for thrombin. GPVI is a major collagen receptor on platelets, making it an ideal target for safe and effective antithrombotic treatment. Therefore, GPVI antago
价 格:¥电议型 号:T61811产 地:中国大陆
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T618075-HT6/7 antagonist 1;5-HT6/7拮抗剂15-HT6/7 antagonist 1
5-HT6/7 antagonist 1 is a dual 5-HT6/7/2A and D2 receptor antagonist for the study of dementia and Alzheimer´s disease.
价 格:¥电议型 号:T61807产 地:中国大陆
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T61788TRPV1 antagonist 3;化合物 TRPV1 antagonist 3TRPV1 antagonist 3
TRPV1 antagonist 3 (Compound 7q) is a highly potent antagonist of the TRPV1 receptor with an IC50 of 2.66 nM against capsaicin. It exhibits selectivity towards its mode of action and is orally bioavailable (with a bioavailability of 60%). Additionally, it can penetrate the central nervous system [1].
价 格:¥电议型 号:T61788产 地:中国大陆
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T61744A1/A3 AR antagonist 2;化合物 A1/A3 AR antagonist 2A1/A3 AR antagonist 2
The compound is an a1/a3 adenosine receptor antagonist, which helps to treat (neurological) inflammatory diseases.
价 格:¥电议型 号:T61744产 地:中国大陆