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T38111Dimethyl-W84 (dibromide);Dimethyl-W84 (dibromide)Dimethyl-W84 (dibromide);Dimethyl-W84 (dibromide)
Dimethyl-W84 is a selective allosteric modulator of the M2 muscarinic acetylcholine receptor. It hinders the dissociation of the orthosteric antagonist N-methylscopolamine from the M2 receptor with an EC50 value of 3 nM.
价 格:¥电议型 号:T38111产 地:中国大陆
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T37727Methimepip dihydrobromide;Methimepip dihydrobromideMethimepip dihydrobromide
Methimepip dihydrobromide is a selective H3R agonist.
价 格:¥电议型 号:T37727产 地:中国大陆
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T37702Pancuronium (bromide hydrate);Pancuronium (bromide hydrate)Pancuronium (bromide hydrate)
Pancuronium is an aminosteroid antagonist of muscle-type nicotinic acetylcholine receptors (nAChRs) with an IC50value of 14.8 nM using patch clamp electrophysiology in BOSC23 cells expressing mouse nAChRs.1It acts as a non-depolarizing neuromuscular blocking agent.2Pancuronium enhances anesthesia induced by isoflurane , reducing immobilization with an ED50value of 1.62 μg/kg.3
价 格:¥电议型 号:T37702产 地:中国大陆
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T37657Mitochondrial respiration-IN-1 hydrobromide;Mitochondrial respiration-IN-1 hydrobromideMitochondrial
Mitochondrial respiration-IN-1 hydrobromide (compound 49) is a potent mitochondrial inhibitor (IC50=8.8 mg/mL). Mitochondrial respiration-IN-1 hydrobromide significantly reduces mitochondrial respiration in platelets[1].
价 格:¥电议型 号:T37657产 地:中国大陆
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T37519Diquat (bromide)Diquat (bromide)Diquat (bromide)
Diquat is a bipyridylium herbicide that, as a stable radical, acts as an electron acceptor in the electron transport chain and is reoxidized by molecular oxygen, producing reactive oxygen species (ROS).1Diquat administration has been used to induce oxidative stressin vitroand in animal models.2,3,4It increases the production of ROS and decreases the mitochondrial membrane potential in mitochondria isolated from porcine intestine leading to mitophagy when administered at a dose of 100 mg/kg.2Form
价 格:¥电议型 号:T37519产 地:中国大陆
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T36947Pyrithiamine (hydrobromide);Pyrithiamine (hydrobromide)Pyrithiamine (hydrobromide)
Pyrithiamine is the pyridine analog of thiamine that prevents growth of organisms that require intact thiamine. [1] It inhibits the growth of bacterial and fungal species at a pyrithiamine:thiamine ratio of 10:1 in growth media and induces symptoms of thiamine deficiency in mice at a dietary ratio of 3:1. These effects are reversible with addition of sufficient thiamine in all species. Pyrithiamine inhibits the formation of cocarboxylase from thiamine in chicken blood in a dose-dependent manner.
价 格:¥电议型 号:T36947产 地:中国大陆
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T36879L-Leucyl-L-Leucine methyl ester hydrobromide;H-Leu-Leu-OMe . HBrL-Leucyl-L-Leucine methyl ester hydr
The lysosomotropic dipeptide LLME has selective toxicity for NK cells, CTL, and M phi without adverse effects on a variety of other lymphoid or nonlymphoid cell types. See also E-2080.
价 格:¥电议型 号:T36879产 地:中国大陆
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T3637Pifithrin-β hydrobromide;化合物Pifithrin-β hydrobromideCyclic PFT-α|||PFT-β|||Cyclic Pifithrin-α hydrob
Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo; protects mice from the side-effects of Y therapy associated with p53 induction. Supresses self-renewal of embryonic stem cells. Also aryl hydrocarbon receptor (AHR) agonist, causes upregulation of AHR target gene CYP1A1 (EC50 = 1.1 μM).
价 格:¥电议型 号:T3637产 地:中国大陆
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T36357Dimethyldioctadecylammonium (bromide);Dimethyldioctadecylammonium (bromide)Dimethyldioctadecylammoni
Dimethyldioctadecylammonium (DDA) is a cationic amphipathic lipid. DDA liposomes containing an Ag85B-ESAT-6 antigen induce antigen deposition at an intramuscular or subcutaneous injection site in mice, increasing immune cell exposure to the antigen. In a guinea pig model of M. tuberculosis infection, spleen bacterial load is reduced and lung and spleen lesion numbers are decreased when the mycobacterial lipid antigens Ac2SGL and PIM2 are administered in liposomes comprised of DDA and a synthetic
价 格:¥电议型 号:T36357产 地:中国大陆
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T36241Arecaidine propargyl ester (hydrobromide)Arecaidine propargyl ester (hydrobromide)Arecaidine proparg
Arecaidine propargyl ester is an agonist of M2muscarinic acetylcholine receptors (mAChRs).1It selectively binds to M2over M1, M3, M4, and M5mAChRs in CHO cells expressing the human receptors (Kis = 0.0871, 1.23, 0.851, 0.977, and 0.933 μM, respectively). Arecaidine propargyl ester induces contractions in isolated guinea pig atrium (pD2= 8.67). It induces apoptosis and the production of reactive oxygen species (ROS) in U87 and U251 glioblastoma cells when used at a concentration of 100 μM.2Arecai
价 格:¥电议型 号:T36241产 地:中国大陆
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T35723GRK-IN-1;4-Amino-5-(bromomethyl)-2-methylpyrimidine (hydrobromide)GRK-IN-1
4-Amino-5-(bromomethyl)-2-methylpyrimidine is a heterocyclic building block.1,2 It has been used in the synthesis of vitamin B1 analogs and thiaminephosphoric acid esters.
价 格:¥电议型 号:T35723产 地:中国大陆
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T3524Halofuginone hydrobromide;常山酮溴酸盐Tempostatin|||RU-19110 (hydrobromide)|||Stenorol;卤夫酮溴氢酸盐|||Tempostat
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor cell growth. Halofuginone Hydrobromide is the hydrobromide salt of halofuginone, a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities. These effects appear to be due to halofuginone-
价 格:¥电议型 号:T3524产 地:中国大陆
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T35172Xenytropium bromide;化合物 T35172N399|||N-399|||N 399;N399|||N-399|||N 399
Xenytropium bromide is a biochemical.
价 格:¥电议型 号:T35172产 地:中国大陆
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T34784TAN67;化合物 T34784SB-205607 dihydrobromide|||SB 205607 dihydrobromide|||SB205607 dihydrobromide|||TAN-
TAN67 is the first effective selective non-peptide delta1 opioid receptor.
价 格:¥电议型 号:T34784产 地:中国大陆
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T34753Suxamethonium bromide;化合物 T34753L.T. 1|||370 I.S.|||Brevidil M;L.T. 1|||370 I.S.|||Brevidil M
Suxamethonium bromide can be used to cause short-term paralysis as part of general anesthesia.
价 格:¥电议型 号:T34753产 地:中国大陆
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T34649Sintropium bromide;化合物 T34649VAL4000|||VAL 4000|||VAL-4000;VAL4000|||VAL 4000|||VAL-4000
Sintropium bromide is a biochemical.
价 格:¥电议型 号:T34649产 地:中国大陆
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T34164Propyromazine bromide;化合物 T34164LD335|||LD 335|||Diospasmyl|||LD-335|||NSC 169416;LD335|||LD 335|||D
Propyromazine bromide is an aticholinergic.
价 格:¥电议型 号:T34164产 地:中国大陆
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T34074Piproctanyl bromide;化合物 T34074Piproctanylium bromide|||Stemtrol;Piproctanyl bromide|||Stemtrol|||Pip
Piproctanyl bromide is an agricultural growth regulator.
价 格:¥电议型 号:T34074产 地:中国大陆
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T34005Phenol, m-(2-(N-methylphenethylamino)ethyl)-, hydrobromide;化合物 T34005Phenol, m-(2-(N-methylphenethyl
Phenol, m-(2-(N-methylphenethylamino)ethyl)-, hydrobromide is a bioactive chemical.
价 格:¥电议型 号:T34005产 地:中国大陆
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T34002Phenol, m-(2-(dipropylamino)ethyl)-, hydrobromide;化合物 T34002Phenol, m-(2-(dipropylamino)ethyl)-, hyd
Phenol, m-(2-(dipropylamino)ethyl)-, hydrobromide is a bioactive chemical.
价 格:¥电议型 号:T34002产 地:中国大陆