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T16918SPDP-PEG6-NHS ester；化合物 T16918SPDP-PEG6-NHS ester
SPDP-PEG6-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T16918产 地：中国大陆
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T16917SPDP-PEG4-NHS ester；化合物 T16917SPDP-PEG4-NHS ester
SPDP-PEG4-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T16917产 地：中国大陆
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T16916SPDP-PEG4-acid；化合物 T16916SPDP-PEG4-acid
SPDP-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T16916产 地：中国大陆
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T16915SPDP-C6-NHS ester；化合物 T16915SPDP-C6-NHS ester
SPDP-C6-NHS ester is an alkyl/ether-based linker utilized in the synthesis of PROTACs[1].
价 格：￥电议型 号：T16915产 地：中国大陆
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T16914SP187；化合物SP187UV4|||MON-?DNJ；UV4|||MON-?DNJ
SP187 (MON-?DNJ) is a host-targeted iminosugar. It has anti-filovirus infection activity.SP187 is used for therapeutic use against influenza and dengue viruses.
价 格：￥电议型 号：T16914产 地：中国大陆
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T16758Rispenzepine；利喷西平Rispenzepine
Rispenzepine is a novel antagonist of muscarinic acetylcholine receptors (mAChRs), selectively targeting the M1 and M3 receptor subtypes, and can be used in the treatment of immune system disorders, infections, and respiratory diseases.
价 格：￥电议型 号：T16758产 地：中国大陆
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T16697Pyronaridine tetraphosphate；磷酸咯萘啶Pyronaridine tetraphosphate
Pyronaridine tetraphosphate is an orally active, mannitol-containing inhibitor of DNA topoisomerase 2 and erythrocyte cytokine with antimalarial and antitumour activity.Pyronaridine tetraphosphate treats P. falciparum and Echinococcus granulosus infections. Pyronaridine tetraphosphate treats P. falciparum and Echinococcus granulosus infections and attenuates Ebola virus transmission.
价 格：￥电议型 号：T16697产 地：中国大陆
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T1663Deoxythymidine triphosphate；2’-脱氧胸苷5’-三磷酸Deoxythymidine triphosphate
Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.
价 格：￥电议型 号：T1663产 地：中国大陆
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T16527Phytic acid dodecasodium salt hydrate；植酸十二钠盐myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium
Phytic acid dodecasodium salt hydrate (myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate) is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium salt hydrate inhibits the enzymatic superoxide source xanthine oxidase with an IC50 of 6 mM and has antioxidative, neuroprotective, and anti-inflammatory effects.
价 格：￥电议型 号：T16527产 地：中国大陆
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T16458PEG4-bis(phosphonic acid diethyl ester)；化合物 T16458PEG4-bis(phosphonic acid diethyl ester)
PEG4-bis(phosphonic acid diethyl ester) is a polyethylene glycol (PEG) derivative serving as a linker for PROTAC synthesis. It is specifically designed for the creation of proteolysis-targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T16458产 地：中国大陆
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T16455PEG3-bis(phosphonic acid diethyl ester)；化合物 T16455PEG-3-bis(phosphonic acid diethyl ester)|||PEG3-bi
PEG3-bis(phosphonic acid diethyl ester) is a polyethylene glycol (PEG) derived linker specifically designed for use in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T16455产 地：中国大陆
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T16453PEG2-bis(phosphonic acid diethyl ester)；化合物 T16453PEG2-bis(phosphonic acid diethyl ester)
PEG2-bis(phosphonic acid diethyl ester) is a polyethylene glycol (PEG) derivative commonly employed as a linker in proteolysis-targeting chimeras (PROTACs) synthesis[1].
价 格：￥电议型 号：T16453产 地：中国大陆
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T16364Infigratinib phosphate；磷酸英非替尼NVP-BGJ398 phosphate|||BGJ-398 phosphate；NVP-BGJ398 phosphate|||BGJ-398
Infigratinib phosphate (BGJ-398 phosphate) is an effective inhibitor of the FGFR family (IC50: 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively).
价 格：￥电议型 号：T16364产 地：中国大陆
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T16328Nitroaspirin；2-乙酰氧基苯甲酸-3-硝酸甲基苯酯NCX 4016；2-乙酰氧基苯甲酸-3-硝酸甲基苯酯|||NCX 4016
Nitroaspirin (NCX 4016) is a nitric oxide donor and a nitro-derivative of Aspirin, which combines with Nitroaspirin to inhibit cyclooxygenase. Nitroaspirin induces significant induction of cell cycle arrest and apoptosis in Cisplatin-resistant human ovarian cancer cells via down-regulation of EGFR/PI3K/STAT3 signaling and modulation of Bcl-2 family proteins. Nitroaspirin has antithrombotic and antiplatelet properties and acts as a direct and irreversible inhibitor of COX-1.
价 格：￥电议型 号：T16328产 地：中国大陆
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T16165Myriocin多球壳菌素ISP-I|||Thermozymocidin
Myriocin (Thermozymocidin), a metabolite derived from Myriococcum albomyces, is a serine-palmitoyltransferase (SPT) inhibitor with potential antitumour, anticancer, and antiparasitic activities.Myriocin inhibits tumour growth by regulating macrophage polarisation and function through the PI3K/Akt/mTOR pathway.Myriocin inhibits HCV infection and can be used in the study of neurological diseases. Myriocin inhibits HCV infection and can be used to study neuropathy and fungal infections.
价 格：￥电议型 号：T16165产 地：中国大陆
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T1616Cefotiam hydrochloride；盐酸头孢替安Pansporin|||SCE-963 hydrochloride|||Pansporine|||Cefotiam dihydrochlori
Cefotiam hydrochloride (SCE-963 hydrochloride) is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.
价 格：￥电议型 号：T1616产 地：中国大陆
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T16083Mizagliflozin；化合物MizagliflozinGSK-1614235 free base|||KGA-3235 free base|||DSP-3235 free base；GSK-16
Mizagliflozin (GSK-1614235 free base) is a sodium-glucose transporter inhibitor( Ki of 27 nM for human SGLT1). Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic drug that can modify postprandial blood glucose excursion. Mizagliflozin also exhibits potential in the amelioration of chronic constipation.
价 格：￥电议型 号：T16083产 地：中国大陆
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T16012Marizomib；马里佐米NPI-0052|||Salinosporamide A|||ML858；NPI-0052|||Salinosporamide A|||ML858
Marizomib (ML858) is a novel irreversible brain-permeable proteasome inhibitor that inhibits CT-L (β5), CT-T-laspase-like (C-L, β1), and trypsin-like (T-L, β2) 20S proteasomes with IC50s of 3.5, 28, and 430 nM, respectively.
价 格：￥电议型 号：T16012产 地：中国大陆
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T15727Sonidegib diphosphate；化合物Erismodegib diphosphateNVP-LDE 225 diphosphate|||Erismodegib diphosphate|||
Sonidegib diphosphate (LDE225 diphosphate) is an effective and selective Smo antagonist (IC50: 1.3 nM and 2.5 nM for mouse and human Smo in a binding assay, respectively).
价 格：￥电议型 号：T15727产 地：中国大陆
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T15724LC-PEG8-SPDP；化合物 T15724LC-PEG8-SPDP
LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T15724产 地：中国大陆
