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T18678SC-VC-PAB-DM1;化合物 T18678SC-VC-PAB-DM1
SC-VC-PAB-DM1 is a drug-linker conjugate utilized in Antibody-Drug Conjugates (ADC), featuring DM1 (Mertansine, a tubulin inhibitor) linked through the SC-VC-PAB[1] ADC linker to deliver potent antitumor activity.
价 格:¥电议型 号:T18678产 地:中国大陆
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T18677SC-Val-Cit-PAB;化合物 T18677SC-Val-Cit-PAB
SC-Val-Cit-PAB is a cleavable ADC linker for antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T18677产 地:中国大陆
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T1856TPT-260 Dihydrochloride;化合物TPT-260TPT-260|||TPT 260|||NSC55712|||TPT260|||TPU-260 Dihydrochloride;TP
TPT-260 Dihydrochloride (NSC55712) is a thiophene thiourea derivative with molecule weight 260.00 in free base form.
价 格:¥电议型 号:T1856产 地:中国大陆
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T1852Rac-Belinostat;化合物BelinostatNSC726630|||PXD101|||PX-105684;NSC726630|||PXD101|||PX-105684
Rac-Belinostat (PX-105684) is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.
价 格:¥电议型 号:T1852产 地:中国大陆
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T18383N-(Azido-PEG3)-N-Fluorescein-PEG4-acid;化合物 T18383N-(Azido-PEG3)-N-Fluorescein-PEG4-acid
N-(Azido-PEG3)-N-Fluorescein-PEG4-acid is a PEG-based PROTAC linker employed for the synthesis of PROTACs[1].
价 格:¥电议型 号:T18383产 地:中国大陆
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T1816(Z)-JIB-04;化合物Z-JIB-04NSC 693627|||Z-JIB-04;NSC 693627|||Z-JIB-04
(Z)-JIB-04 (NSC 693627) is an isomer of JIB-04.
价 格:¥电议型 号:T1816产 地:中国大陆
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T1798RITA;化合物RITANSC 652287|||RITA (NSC 652287);NSC 652287|||RITA (NSC 652287)
RITA (NSC-652287)(NSC-652287) induced cross-links of both DNA-DNA and DNA-protein with no detectable DNA single-strand breaks. RITA, like nutlin-3, can disrupt the p53/Mdm2 interaction.
价 格:¥电议型 号:T1798产 地:中国大陆
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T17944Fluorescein-PEG5-NHS ester;化合物 T17944Fluorescein-PEG5-NHS ester
Fluorescein-PEG5-NHS ester, a PEG-based PROTAC linker, facilitates PROTAC synthesis[1].
价 格:¥电议型 号:T17944产 地:中国大陆
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T1780LParecoxib sodium帕瑞昔布钠SC 69124A|||SC-69124A|||帕瑞昔布钠|||SC69124A|||Dynastat
Parecoxib is a cyclooxygenase-2 inhibitor used for the short-term treatment of postoperative pain in adults. Parecoxib is a water-soluble and injectable prodrug of valdecoxib. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib and rofecoxib. ketorolac has a much higher gastrointestinal toxicity profile compared to most other nonsteroidal anti-inflammatory drugs including ibuprofen and Naprosyn.
价 格:¥电议型 号:T1780L产 地:中国大陆
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T1780Parecoxib;帕瑞昔布SC 69124|||Vorth-P|||Valus-P;SC 69124|||帕瑞昔布|||Vorth-P|||Valus-P
Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor.
价 格:¥电议型 号:T1780产 地:中国大陆
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T17708Carboxyfluorescein-PEG12-NHS;化合物 T17708Carboxyfluorescein-PEG12-NHS
Carboxyfluorescein-PEG12-NHS is a polyethylene glycol (PEG)-based PROteolysis TArgeting Chimera (PROTAC) linker. It serves as a crucial component in synthesizing PROTACs, a class of molecules designed for targeted protein degradation[1].
价 格:¥电议型 号:T17708产 地:中国大陆
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T17303α-Cyclodextrin;α-环糊精Alfadex|||NSC269470|||NSC 269470|||NSC-269470;Alfadex|||NSC269470|||α-环糊精|||NSC
α-Cyclodextrin (Alfadex) is a soluble fiber derived from corn and has beneficial effects on weight management in obese individuals with type 2 diabetes.
价 格:¥电议型 号:T17303产 地:中国大陆
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T1724SCR7 pyrazine;SCR7 吡嗪SCR7;SCR7|||SCR7 吡嗪
SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).
价 格:¥电议型 号:T1724产 地:中国大陆
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T17216Valspodar;伐司扑达PSC 833;PSC 833
Valspodar (PSC 833) is a specific P-glycoprotein inhibitor and MDR regulator often used as a chemical sensitizer to study advanced epithelial ovarian cancer.
价 格:¥电议型 号:T17216产 地:中国大陆
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T17214Valencene;凡伦橘烯(NSC 148969|||NSC-148969|||NSC148969;NSC 148969|||NSC-148969|||NSC148969
Valencene (NSC-148969) is a sesquiterpenoid isolated from Cyperus rotundus and is an aroma component of citrus fruits and citrus-derived odors.ValenceneValencene has anti-allergic, anti-inflammatory, anti-melanogenic, and antioxidant activities. Valencene inhibits the overexpression of Th2 chemokines and pro-inflammatory chemokines by blocking the NF-κB pathway.
价 格:¥电议型 号:T17214产 地:中国大陆
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T1720LAmfenac;化合物 T1720LNSC309467|||NSC-309467|||NSC 309467;NSC309467|||NSC-309467|||NSC 309467
Amfenac promotes apoptosis in ARPE-19 cell culture.
价 格:¥电议型 号:T1720L产 地:中国大陆
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T17192Ubiquitin Isopeptidase Inhibitor I, G5;Ubiquitin Isopeptidase 抑制剂INSC144303;NSC144303
Ubiquitin Isopeptidase Inhibitor I, G5 is a caspase-independent inducer of cell necrosis that induces cell death via the death receptor pathway (IC50 of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively).
价 格:¥电议型 号:T17192产 地:中国大陆
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T17159Treosulfan;曲奥舒凡NSC 39069|||Treosulphan;NSC 39069|||曲奥舒凡|||Treosulphan
Treosulfan (Treosulphan) is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types.
价 格:¥电议型 号:T17159产 地:中国大陆
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T17155Trabectedin;曲贝替定Ecteinascidin 743|||ET-743;Ecteinascidin 743|||曲贝替定|||ET-743
Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research. Trabectedin inhibits cell growth of MX-1, MCF7 and MCF7/DXR cells with IC50 values of 0.1 nM, 1.5 nM and 3.7 nM, respectively.
价 格:¥电议型 号:T17155产 地:中国大陆
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T17059Tetrahydrouridine;四氢尿苷NSC 112907|||NSC112907|||NSC-112907;NSC 112907|||NSC112907|||四氢尿苷|||NSC-112907
Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator. It can be used in cancer treatment to make tumor cells more sensitive to radiation therapy. THU is a competitive cytidine deaminase(CDA) inhibitor that inhibits deamination in the catabolism of cytotoxic deoxycytidine analogs such as ara-C and Gemcitabine.
价 格:¥电议型 号:T17059产 地:中国大陆