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T22259AMG-Tie2-1；4-甲基-3-[[3-[2-(甲基氨基)-4-嘧啶基]-2-吡啶基]氧基]-N-[3-(三氟甲基)苯基]苯甲酰胺AMG-Tie2；AMG-Tie2|||4-甲基-3-[[3-[2
AMG-Tie2-1 is a dual inhibitor of VEGF receptor 2 (VEGFR2) and tunica interna endothelial cell kinase 2 (Tie2).
价 格：￥电议型 号：T22259产 地：中国大陆
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T22202-Methoxyestradiol二甲氧基雌二醇2-甲氧雌二醇|||二甲氧基雌二醇|||NSC-659853|||2-MeOE2|||2-ME2
2-Methoxyestradiol (2-ME2) is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing endothelial cell proliferation and inducing endothelial cell apoptosis. This agent also inhibits tumor cell growth by binding to tubulin, resulting in antimitotic activity, and by inducing caspase activation, resulting in cell cycle arrest in the G2 phase, DNA fragmentation, and apoptosis.
价 格：￥电议型 号：T2220产 地：中国大陆
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T22159TCS HDAC6 20b；化合物 T22159TCS HDAC6 20b
TCS HDAC6 20b is a HDAC6 -selective inhibitor that blocks the growth of estrogen receptor α-positive breast cancer MCF-7 cells [1].
价 格：￥电议型 号：T22159产 地：中国大陆
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T22154SR 2595；化合物 T22154SR 2595
SR2595 is an inverse agonist of nuclear receptor PPARγ with an IC 50 of 30 nM [1].
价 格：￥电议型 号：T22154产 地：中国大陆
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T21996Zoniporide hydrochloride；化合物ZoniporideCP-597396 hydrochloride；CP-597396 hydrochloride
Zoniporide hydrochloride is a selective inhibitor of NHE-1 with IC50 of 14 nM which is >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride shows an IC50 of 59 nM for NHE-1-dependent swelling of human platelets.
价 格：￥电议型 号：T21996产 地：中国大陆
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T21979P32/98 hemifumarate；异亮氨酸噻唑烷半富马酸盐P32/98 (hemifumarate)(136259-20-6 free base)；P32/98 (hemifumarate)(1
P32/98 hemifumarate is a dipeptidyl peptidase IV (DPP4) inhibitor with hypoglycemic properties that improves insulin sensitivity and β-cell responsiveness in the Zucker diabetic rat model, and may be useful in studies of type 2 diabetes and colitis.
价 格：￥电议型 号：T21979产 地：中国大陆
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T21872CCT018159；化合物CCT018159CCT018159
CCT018159 is a 3,4-diarylpyrazole resorcinol, an ATP-competitive HSP90ATPase inhibitor that inhibits human Hsp90β and yeast Hsp90 with IC50s of 3.2 and 6.6 μM, respectively.CCT018159 inhibits key endothelial and tumor cell functions associated with invasion and angiogenesis. CCT018159 caused cellular inhibition associated with G1 phase block and induced apoptosis.
价 格：￥电议型 号：T21872产 地：中国大陆
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T21859ARM1；化合物ARM1ARM1
ARM1 is a potent inhibitor of aminopeptidase and epoxide hydrolase. The IC50 values are 7.61 ?M for aminopeptidase and 12.4 ?M for epoxide hydrolase.
价 格：￥电议型 号：T21859产 地：中国大陆
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T21821LREV 5901A；化合物 REV 5901AREV 5901 HCl|||REV 5901A（101910-24-1 Free base）；REV 5901 HCl|||REV 5901A（1019
REV 5901A (REV 5901 HCl) is an orally active leukotriene receptor antagonist and 5-lipoxygenase inhibitor with antimicrobial activity that attenuates colon cancer growth in mice.REV 5901A has been used in studies of asthma and myocardial infarction. REV 5901A is used to study asthma and myocardial infarction.
价 格：￥电议型 号：T21821L产 地：中国大陆
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T21821REV 5901；化合物 T21821REV 5901
REV 5901 is a competitive and orally effective antagonist of leukotriene receptor, with a Ki of 0.7 μM. REV 5901 is also a 5-lipoxygenase inhibitor. REV 5901 can be used for the research of asthma in which leukotriene release be involved [1] [2].
价 格：￥电议型 号：T21821产 地：中国大陆
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T21777VU0359595；化合物VU0359595VU0359595-1|||CID-53361951|||ML-270；VU0359595-1|||CID-53361951|||ML-270
VU0359595 (ML-270) is a potent and selective pharmacological phospholipase D1 (PLD1) inhibitor with an IC50 of 3.7 nM. VU0359595 is >1700-fold selective for PLD1 over PLD2 (IC50 of 6.4 μM). VU0359595 can be used for the research of cancer, diabetes, neurodegenerative and inflammatory diseases.
价 格：￥电议型 号：T21777产 地：中国大陆
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T21660Lb-Casomorphin (1-3) Acetate；化合物b-Casomorphin (1-3) Acetateb-Casomorphin (1-3) Acetate (72122-59-9 Fr
b-Casomorphin (1-3) Acetate is a tri-peptide with an opioid effect.
价 格：￥电议型 号：T21660L产 地：中国大陆
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T21602PF-04880594；化合物 T21602PF-04880594
PF-04880594 is a potent and selective RAF inhibitor which inhibits both wild-type and mutant BRAF and CRAF. PF-04880594 exhibits antitumor activity [1].
价 格：￥电议型 号：T21602产 地：中国大陆
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T21598LG3335 Acetate；化合物G3335 AcetateG3335 Acetate (36099-95-3 free base)；G3335 Acetate (36099-95-3 free ba
G3335 Acetate was discovered to be a novel PPARgamma antagonist.
价 格：￥电议型 号：T21598L产 地：中国大陆
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T21598G3335；化合物 T21598G3335
H- Trp- Glu- OH is a selective, reversible and cell-permeable PPARγ with a K d of ~8 μM, which might be developed as a possible lead compound in diabetes research [1].
价 格：￥电议型 号：T21598产 地：中国大陆
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T21593AAL-993；化合物AAL-993AAL-993
AAL-993 is a potent VEGFR inhibitor with IC50s of 130 nM, 23 nM and 18 nM for VEGFR1, VEGFR2 and VEGFR3, respectively. AAL993 has a weak inhibitory effect on other tyrosine kinases. AAL993 also shows potent antiangiogenic and antitumor activities.
价 格：￥电议型 号：T21593产 地：中国大陆
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T215911H-1-ethyl Candesartan Cilexetil；坎地沙坦酯杂质E1H-1-ethyl Candesartan Cilexetil
1H-1-ethyl Candesartan Cilexetil is a process-related impurity in the bulk synthesis of candesartan cilexetil, which is a potent, long-acting and selective angiotensin II type 1 receptor (AT1) antagonist.
价 格：￥电议型 号：T21591产 地：中国大陆
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T2159CaMKP Inhibitor；化合物CaMKP InhibitorCaMKP Inhibitor
CaMKP Inhibitor can inhibit CaMKP.
价 格：￥电议型 号：T2159产 地：中国大陆
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T21559OTSSP167 hydrochlorideOTSSP 167 盐酸盐OTSSP 167 盐酸盐
OTSSP167 hydrochloride is a highly potent inhibitor of MELK(IC50 : 0.41 nM).
价 格：￥电议型 号：T21559产 地：中国大陆
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T21544AZD-5597；化合物AZD-5597(S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)
AZD-5597 ((S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(methylamino)pyrrolidin-1-yl)methanone) is a potent imidazole pyrimidine amide CDK inhibitor.
价 格：￥电议型 号：T21544产 地：中国大陆
