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T16947SU16f
SU16f is a potent and selective PDGFRβ inhibitor (IC50s: 10 nM, 140 nM, 2.29 μM for PDGFRβ, PDGFR1, PDGFR2, respectively). Neutralization of PDGFRβ receptor by SU16f blocks the promoting role of GC-MSCs conditioned medium in gastric cancer cell proliferation and migration.
价 格：￥电议型 号：T16947产 地：中国大陆
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T8816NAE-IN-M22NAEINM22,cancer,Inhibitor,NAE-IN-M-22,NAE,NEDD8,NAE IN M22,enzyme,activating,inhibit,tumor
NAE-IN-M22 is a selective, potent and reversible inhibitor of NEDD8 activating enzyme (NAE). NAE-IN-M22 inhibits multiple cancer cell lines and induces apoptosis in A549 cells. NAE-IN-M22 also can inhibit tumor growth in vivo.
价 格：￥电议型 号：T8816产 地：中国大陆
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T11016DGAT-1 inhibitor 2DGAT 1 inhibitor 2,DGAT1 inhibitor 2
DGAT-1 inhibitor 2 is an effective DGAT-1 inhibitor; anti-obesity drug. Objective: DGAT-1 acyl-CoA: diacylglycerol acyltransferase 1 (DGAT1) is one of two known DGAT enzymes that catalyze the final step of triglyceride synthesis. The discovery of transgenic mice and pharmacological studies indicate that inhibiting DGAT1 is a promising strategy for treating obesity and type 2 diabetes.
价 格：￥电议型 号：T11016产 地：中国大陆
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T16581Progabide
Progabide is an agonist of the gamma-aminobutyric acid receptor.
价 格：￥电议型 号：T16581产 地：中国大陆
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TQ0216Ercalcitriol
Ercalcitriol is an active metabolite of vitamin D2. Ercalcitriol, as the physiological activated form of vitamin D, can strengthen immunity via regulation of cathelicidin antimicrobial peptide (CAMP) and defensin β-4 (DEFB4) genes in normal and transformed cells to combat pathogenic infections.
价 格：￥电议型 号：TQ0216产 地：中国大陆
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TN11601,2,3,6-TetragalloylglucoseInhibitor,1,2,3,6-Tetragalloylglucose,1,2,3,6Tetragalloylglucose,inhibit,
1,2,3,6-Tetragalloylglucose has antioxidative activity, it also shows the most potent anticomplement activity (IC50 = 34 microM). 1,2,3,6-Tetragalloylglucose is also a potent inhibitor of UDP glucuronosyltransferase 1 A1 (UGT1A1, Ki = 1.68 μM).
价 格：￥电议型 号：TN1160产 地：中国大陆
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T8500VLX600iron,HCT116,Autophagy,glycolytic,VLX 600,colon,chelator,cancer,OXPHOS,VLX600,Mitochondrial Met
VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent. It acts by reducing mitochondrial oxidative phosphorylation in tumor cells.
价 格：￥电议型 号：T8500产 地：中国大陆
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T9117BSJ-4-116CDK,degrader,antiproliferative,inhibit,Kelly,C1039F,BSJ 4 116,Cyclin dependent kinase,PROTA
BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. It downregulates DDR genes through a premature termination of transcription, primarily through increasing poly(adenylation).
价 格：￥电议型 号：T9117产 地：中国大陆
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T9104TJ191cancer,TJ 191,Apoptosis,PMBC,MOLT-3,CEM,inhibit,C8166,Inhibitor,MOLT-4,MT-2,TJ191,HSB-2,TJ-191,
TJ191 is a selective anti-cancer agent, targeting low TβRIII-expressing malignant T-cell leukemia/lymphoma cells.
价 格：￥电议型 号：T9104产 地：中国大陆
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TQ0116LY 3000328Cathepsin,LY3000328,LY 3000328,Inhibitor,LY-3000328,inhibit
LY 3000328 is a potent, highly selective Cathepsin S (Cat S) inhibitor (IC50s: 7.7 and 1.67 nM for hCat S and mCat S).
价 格：￥电议型 号：TQ0116产 地：中国大陆
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T8416Capmatinib xHClApoptosis,c-Met/HGFR,ATP competitive,inhibit,INC-280,Inhibitor,Capmatinib,SNU-5,INCB-
Capmatinib xHCl is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activity in cells (IC50 values range from 0.3 to 1.1 nM).
价 格：￥电议型 号：T8416产 地：中国大陆
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T9169MPP+ iodideMPP+,Mitochondrial Metabolism,dopaminergic,neurons,MPP+ iodide,respiratory,chain,Inhibito
MPP+ iodide, the metabolite of a neurotoxin MPTP, causes symptom of Parkinson´s disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces dopamine transporter (DAT) externalization in dopaminergic (DA) neurons, but internalization of serotonin transporter (SERT) in serotonergic (5-HT) neurons. MPP+ induces autophagic cell death in SH-SY5Y cells.
价 格：￥电议型 号：T9169产 地：中国大陆
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TP1682LAbz-FR-K(Dnp)-P-OH acetate(500799-61-1 free base)Abz FR K(Dnp) P OH acetate(500799 61 1 free base)
Abz-FR-K(Dnp)-P-OH acetate is an excellent angiotensin I-converting enzyme (ACE) substrate with a Km value of 4.0 μM and a kcat value of 210s-1.
价 格：￥电议型 号：TP1682L产 地：中国大陆
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T7394Toceranib PhosphateSU11654,inhibit,SU-11654,Toceranib,Toceranib Phosphate,VEGFR,PHA 291639E,Platelet
Toceranib phosphate, is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family, including Flk-1/KDR, PDGFR
价 格：￥电议型 号：T7394产 地：中国大陆
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TP1622DX600 TFADX600 TFA,DX-600 TFA
DX600 TFA is a specific inhibitor of ACE2 and does not cross-react with ACE.
价 格：￥电议型 号：TP1622产 地：中国大陆
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T9073SRS16-86IRI,SRS16-86,Inhibitor,ferrostatin,SRS-16-86,ischemia-reperfusion injury,SCI,spinal cord inj
SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of?ferroptosis.
价 格：￥电议型 号：T9073产 地：中国大陆
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T6116LBleomycin hydrochlorideBleomycinhydrochloride
Bleomycin hydrochloride is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin hydrochloride is an antitumor antibiotic.
价 格：￥电议型 号：T6116L产 地：中国大陆
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T28543RK-9123016
RK-9123016 is a SIRT2 inhibitor. RK-9123016 increases the acetylation level of eukaryotic translation initiation factor 5A (eIF5A), a physiological substrate of SIRT2, and reduces cell viability of human breast cancer cells accompanied with a decrease in c-Myc expression.
价 格：￥电议型 号：T28543产 地：中国大陆
