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T9173HM-30181 mesylate monohydrateHM30181 mesylate monohydrate,HM 30181 mesylate monohydrate
HM-30181 mesylate monohydrate is an oral P-glycoprotein (P-gp) inhibitor, used to enhance the oral bioavailability of P-gp substrate drugs.
价 格:¥电议型 号:T9173产 地:中国大陆
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T6840LFRAX486 HCL(1232030-35-1 free base)FRAX486 HCL(1232030351 free base),FRAX486 HCL(1232030 35 1 free b
FRAX486 HCL is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.
价 格:¥电议型 号:T6840L产 地:中国大陆
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T9307(E)-3-(3,4-dichlorophenyl)-N-(2-(4-(methylsulfonyl)piperazin-1-yl)-2-oxoethyl)acrylamide(E)3(3,4dich
(E)-3-(3,4-dichlorophenyl)-N-(2-(4-(methylsulfonyl)piperazin-1-yl)-2-oxoethyl)acrylamide is a chemical compound.
价 格:¥电议型 号:T9307产 地:中国大陆
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T6S1302CarnosolRibosomal S6 Kinase (RSK),Keap1-Nrf2,Endogenous Metabolite,S6K,inhibit,Carnosol,Inhibitor
Carnosol has anti-oxidative, anti-inflammatory, antiproliferative and apoptosis inducing properties. Carnosol enhances the sensitivity of chemoresistant cancer cells to chemotherapeutic agents. 3. Carnosol may as a novel agonist of TRPA1 with an EC5 value of 12.46 μM.
价 格:¥电议型 号:T6S1302产 地:中国大陆
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TQ0311GSK163090Dopamine Receptor,5-HT1A,GSK163090,Inhibitor,5-hydroxytryptamine Receptor,antidepressant,an
GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).
价 格:¥电议型 号:TQ0311产 地:中国大陆
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T26035rac-NBI-74330
rac-NBI-74330 is an effective and selective CXCR3 antagonist.
价 格:¥电议型 号:T26035产 地:中国大陆
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T6935NirogacestatNirogacestat,γ-secretase,Gamma secretase,cancer,inhibit,PF 3084014,gastrointestinal,toxi
PF-03084014 (PF-3084014) is a specific γ-secretase inhibitor (IC50: 6.2 nM, in a cell-free assay).
价 格:¥电议型 号:T6935产 地:中国大陆
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T9552BAZ1A-IN-1leukemia,breast cancer,Epigenetic Reader Domain,BAZ1A IN 1,cancer,ZR-75–30,BAZ1A,BAZ1AIN1,
BAZ1A-IN-1 is a potent BAZ1A inhibitor with the KD value of 0.52 μM for the BAZ1A bromodomain. BAZ1A-IN-1 shows good anti-survival activity against cancer cell lines with high BAZ1A expression, but weak or no activity against cancer cells with low BAZ1A expression.
价 格:¥电议型 号:T9552产 地:中国大陆
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TP1930L1Spexin acetate(1370290-58-6 free base)Spexin acetate(1370290586 free base),Spexin acetate(1370290 58
Spexin acetate is a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 values are 45.7 and 112.2 nM, respectively). Exhibits no significant activity at galanin receptor 1. Endogenous satiety-inducing peptide; inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet-induced obese mice and rats. Attenuates LH secretion in goldfish. Exhibits anxiolytic effects in vivo.
价 格:¥电议型 号:TP1930L1产 地:中国大陆
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TP1307Buserelin Acetate (57982-77-1 free base)Buserelin Acetate (57982771 free base),Buserelin Acetate (57
Buserelin Acetate is an agonist of gonadotropin-releasing hormone receptor(GnRHR).
价 格:¥电议型 号:TP1307产 地:中国大陆
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T7300GDC-0575GDC 0575,GDC-0575,RG-7741,inhibit,ARRY575,Inhibitor,Checkpoint Kinase (Chk),ARRY 575,GDC0575
GDC-0575 is a highly-selective oral small-molecule Chk1 inhibitor(IC50 of 1.2 nM).
价 格:¥电议型 号:T7300产 地:中国大陆
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T38034MAO-IN-M30 dihydrochloride
MAO-IN-M30 dihydrochloride is a potent and brain selective monoamine oxidase (MAO) inhibitor (EC50 values are 37 and 57 nM for MAO-A and MAO-B, respectively). Also an iron chelator with antioxidant properties. Protects cells against 6-OHDA induced apoptosis. Attenuates MPTP depletion of DA and increases striatal monoamine levels in a mouse Parkinson´s disease model.
价 格:¥电议型 号:T38034产 地:中国大陆
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TP1305LEP(116-130)(mouse)LEP(116-130)(mouse),Inhibitor,LEP(116130)(mouse),inhibit,LEP(116 130)(mouse)
Leptin (116-130),mouse(C64H109N19O24S),a peptide with the sequence Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-NH2. Leptin is an adipocyte-derived hormone that acts as a major regulator for food intake and energy homeostasis.
价 格:¥电议型 号:TP1305产 地:中国大陆
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TN7030Heteroclitin GHeteroclitin G
Heteroclitin G was found as potential biomarkers of KIS blood-replenishing activity, and quantitative analysis provided a research basis for further pharmacological research.
价 格:¥电议型 号:TN7030产 地:中国大陆
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T6730WAY-600inhibit,Inhibitor,mTOR,WAY 600,WAY-600,Mammalian target of Rapamycin
WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308); selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
价 格:¥电议型 号:T6730产 地:中国大陆
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T35530IHMT-PI3Kδ-372IHMTPI3Kδ372,IHMT-PI-3Kδ-372,IHMT PI3Kδ 372
IHMT-PI3Kδ-372 is a selective inhibitor of PI3Kδ with an IC50 of 14 nM and can be used in studies about chronic obstructive pulmonary disease.
价 格:¥电议型 号:T35530产 地:中国大陆
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T6616Ondansetron hydrochlorideGR 38032,Inhibitor,GR-38032,Ondansetron hydrochloride,Ondansetron,SN307,5-H
Ondansetron is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiation therapy.
价 格:¥电议型 号:T6616产 地:中国大陆
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T8300Mogroside IV-EInhibitor,Mogroside IV E,inhibit,Mogroside IV-E
Mogroside IV-E is a triterpenoid glycoside isolated from the extracts of Luo Han Guo. Mogrosides exhibit antidiabetic, antioxidant and anticancer activities.
价 格:¥电议型 号:T8300产 地:中国大陆
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T8307Hydroxy-α-sanshoolEndogenous Metabolite,Hydroxyαsanshool,Transient receptor potential channels,Inhib
Hydroxy- α- sanshool is an alkyl amide isolated from the pepper. It acts as a TRPA1 covalent and TRPV1 non-covalent agonist (EC50s: 69 and 1.1 μM).
价 格:¥电议型 号:T8307产 地:中国大陆
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TQ0306MLN120BMLN120B,ML120B,Inhibitor,I kappa B kinase,inhibit,IKK,IκB kinase,MLN-120B
MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).
价 格:¥电议型 号:TQ0306产 地:中国大陆