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T4S0544Furanodienone呋喃二烯酮;莪术呋喃二烯酮
1. Furanodienone has effects on MCF-7 cells are mediated, at least in part, by inhibiting ERα signaling. 2. Furanodienone inhibits EGFR/HER2 signaling pathway in BT474 and SKBR3 cells, the effect is specifically dependent on the expression of HER2 but not
价 格:¥电议型 号:T4S0544产 地:中国大陆
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T4944Nervonic acidcis-15-Tetracosenoic acid;Selacholeic acid;神经酸
Nervonic acid is a long chain unsaturated fatty acid that is enriched in sphingomyelin. It consists of choline, sphingosine, phosphoric acid, and fatty acid. Nervonic acid may enhance the brain functions and prevent demyelination (Chemical Land21). Resear
价 格:¥电议型 号:T4944产 地:中国大陆
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T4844L-MethionineL-蛋氨酸;L(-)-Methionin;L-Methionin
L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
价 格:¥电议型 号:T4844产 地:中国大陆
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T47445-HYDROXYINDOLE-3-ACETIC ACID5-HIAA;5-羟基吲哚-3-乙酸
5-Hydroxyindoleacetic acid (5HIAA) is a breakdown product of serotonin that is excreted in the urine. Serotonin and 5HIAA are produced in excess amounts by carcinoid tumors, and levels of these substances may be measured in the urine to test for carcinoid
价 格:¥电议型 号:T4744产 地:中国大陆
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T4697ABBV-744ABBV744;ABBV 744
ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.
价 格:¥电议型 号:T4697产 地:中国大陆
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T4692Protein kinase inhibitors 1 hydrochloridProtein kinase inhibitors 1 hydrochlorid (1365986-44-2(free
Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.
价 格:¥电议型 号:T4692产 地:中国大陆
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T4644Tapinarof苯烯莫德;GSK2894512;Benvitimod;WBI 1001
Tapinarof is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.
价 格:¥电议型 号:T4644产 地:中国大陆
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T4544ElbasvirMK-8742
Elbasvir is an inhibitor of nonstructural protein 5A (NS5A) of hepatitis C virus (HCV) being developed as a component of treatment regimens for chronic HCV infection.
价 格:¥电议型 号:T4544产 地:中国大陆
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T4499Mequitazine美喹他嗪;Virginan;Primalan;LM-209;Metaplexan
Mequitazine is an effective, nonsedative and long-acting histamine H1 antagonist.
价 格:¥电议型 号:T4499产 地:中国大陆
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T4498Stiripentol斯利潘托;Diacomit;BCX2600
Stiripentol (STP) is an anticonvulsant agent, which can inhibit N-demethylation of CLB to NCLB mediated by CYP3A4 (noncompetitively) and CYP2C19 (competitively) with Ki of 1.59/0.516 μM and IC50 of 1.58/3.29 μM, respectively.
价 格:¥电议型 号:T4498产 地:中国大陆
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T4497Amifampridine3,4-Pyridinediamine;Pyridine-3,4-Diamine;3,4-Diaminopyridine;阿米吡啶
Amifampridine is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is increased. Ca2+ channels can then be open for a longer ti
价 格:¥电议型 号:T4497产 地:中国大陆
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T4496LM22B-10LM22B10;LM22B 10
LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor and can induce TrkB, TrkC, ERK and AKT activation in vitro and in vivo.
价 格:¥电议型 号:T4496产 地:中国大陆
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T4495dBET1
dBET1 is a hybrid molecule that combines (+)-JQ1 and thalidomide. It induces cereblon-dependent BET protein degradation in vitro (EC50: 430 nM) and induces apoptosis.
价 格:¥电议型 号:T4495产 地:中国大陆
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T4494CLOZAPINE N-OXIDE氯氮平N-氧化;氯氮平N-氧化物
Clozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration [1]. It is produced by the action of cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4, whose activities, in tu
价 格:¥电议型 号:T4494产 地:中国大陆
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T4493BictegravirGS-9883
Bictegravir is a potent inhibitor of HIV-1 integrase (IC50: 7.5 nM).
价 格:¥电议型 号:T4493产 地:中国大陆
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T4492pocapavirV-073;SCH-48973
Pocapavir is an investigational enterovirus (EV) capsid inhibitor.
价 格:¥电议型 号:T4492产 地:中国大陆
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T4491LMPTP INHIBITOR 1 hydrochlorideLMPTP INHIBITOR 1 hydrochloride (1908414-82-3(free base))
LMPTP INHIBITOR 1 is a selective inhibitor of low molecular weight protein tyrosine phosphatase (LMPTP), with an IC50 of 0.8 μM LMPTP-A.
价 格:¥电议型 号:T4491产 地:中国大陆
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T4490PF-01247324PF 01247324;PF01247324
PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).
价 格:¥电议型 号:T4490产 地:中国大陆
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T4489AKT-IN-16-[4-(1-氨基环丁基)苯基]-5-苯基-3-吡啶甲酰胺;AZD-26;AZD 26;AZD26
AZD-26 is an allosteric AKT inhibitor (IC50: 1.04 μM).
价 格:¥电议型 号:T4489产 地:中国大陆
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T4488GSK-25GSK25;GSK 25
GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).
价 格:¥电议型 号:T4488产 地:中国大陆