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T60086TTBK1-IN-2；化合物TTBK1-IN-2N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine；N-[4-(4-chl
TTBK1-IN-2 (N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine) is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 ?M. TTBK1-IN-2 reduces TDP-43 phosphorylation both in cell cultures and the spinal cord of transgenic TDP-43 mice.
价 格：￥电议型 号：T60086产 地：中国大陆
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T60085MM3122；化合物MM3122GTPL11533|||MM-3122|||Ac-GQFR-kbt；GTPL11533|||MM-3122|||Ac-GQFR-kbt
MM3122 (MM-3122) is a selective type II transmembrane serine protease (TMPRSS2) inhibitor, IC50 = 0.34 nM. MM3122 effectively blocks TMPRSS2, thereby inhibiting the entry of SARS-CoV-2 and MERS-CoV into human cells.
价 格：￥电议型 号：T60085产 地：中国大陆
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T60084FINO2；化合物FINO2FINO2
FINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrating stability across varying pH levels. Furthermore, FINO2 induces widespread lipid peroxidation.
价 格：￥电议型 号：T60084产 地：中国大陆
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T60083MMP-12 Inhibitor；化合物MMP-12MMP12|||MMP408；MMP12|||MMP408
MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.
价 格：￥电议型 号：T60083产 地：中国大陆
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T60082HDAC-IN-40；化合物HDAC-IN-40HDAC-IN-40
HDAC-IN-40 is a potent alkoxyamide-based HDAC inhibitor with Ki of 60 nM and 30 nM for HDAC2 and HDAC6, respectively. HDAC-IN-40 had antitumor effects
价 格：￥电议型 号：T60082产 地：中国大陆
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T60081BV02；化合物BV022-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-dioxoisoindoline-5-carbo
BV02 is an inhibitor of 14-3-3 protein-protein interactions and can be used in studies about the treatment of chronic myeloid leukemia. BV02 disrupts hematopoietic cells expressing the IM-resistant T315I mutation and the IM-sensitive wild-type Bcr-Abl.
价 格：￥电议型 号：T60081产 地：中国大陆
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T60080TMPH；化合物TMPH2,2,6,6-Tetramethylpiperidin-4-yl heptanoate；2,2,6,6-Tetramethylpiperidin-4-yl heptanoat
TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.
价 格：￥电议型 号：T60080产 地：中国大陆
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T6008CNX-2006；化合物CNX2006CNX 2006|||CNX2006；CNX 2006|||CNX2006
CNX-2006 is a novel irreversible mutant-selective EGFR inhibitor with IC50 of < 20 nM, with very weak inhibition at wild-type EGFR.
价 格：￥电议型 号：T6008产 地：中国大陆
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T60079GNE-064；化合物GNE-064GNE064；GNE064
GNE-064 is a selective, orally active and highly soluble inhibitor of SMARCA4, SMARCA2 and PBRM1 bromodomains 5. GNE-064 inhibits SMARCA4 with an IC50 of 0.035 μM and inhibits SMARCA2 with an EC50 of 0.10 μM. GNE-064 possess Kds with 0.01, 0.016, 0.018 and 0.049 μM for SMARCA4, SMARCA2, PBRM1 bromodomains 5 and PBRM1 bromodomains 2, repectively. GNE-064 can be used as a chemical probe for the research of drug synthesis.
价 格：￥电议型 号：T60079产 地：中国大陆
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T60078NSC2805；化合物NSC28052-(2,5-dihydroxy-4-methylphenyl)-5-methylbenzene-1,4-diol；2-(2,5-dihydroxy-4-methy
NSC2805 is an inhibitor of WWP2, an E3 ubiquitin ligase with an IC50 of 0.38 μM. NSC2805 can be used in anticancer studies.
价 格：￥电议型 号：T60078产 地：中国大陆
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T60077SCP1-IN-1；化合物SCP1-IN-1SCP1-IN-1
SCP1-IN-1 (compound SH T-62) is a potent and selective covalent inhibitor against SCP1. SCP1-IN-1 promotes REST degradation and reduces transcriptional activity. In some glioblastoma cells, the high level of REST protein drives tumor growth. SCP1-IN-1 has the potential for the research of glioblastoma whose growth is driven by REST transcription activity [1].
价 格：￥电议型 号：T60077产 地：中国大陆
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T60076Oritinib；化合物OritinibSH-1028；SH-1028
Oritinib (SH-1028) is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q), EGFR (L858R/T790M), EGFR (d746-750), EGFR (d746-750/T790M), respectively. Oritinib can be used in studies about the treatment of non-small cell lung cancer.
价 格：￥电议型 号：T60076产 地：中国大陆
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T60075Dopamine D2 receptor agonist-2；化合物 Dopamine D2 receptor agonist-2Dopamine D2 Receptor；Dopamine D2 Re
Dopamine D2 receptor agonist-2 (Dopamine D2 Receptor) is a ligand targeting the dopamine D2 receptor.
价 格：￥电议型 号：T60075产 地：中国大陆
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T60074GPCR agonist-2；化合物 GPCR agonist-24-(Cyclopropylamino)-3-nitrobenzoic acid；4-(Cyclopropylamino)-3-nit
GPCR agonist-2 (4-(Cyclopropylamino)-3-nitrobenzoic acid) is an agonist of the orphan human GPCR GPR109B.
价 格：￥电议型 号：T60074产 地：中国大陆
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T60073Antimycobacterial agent-4；化合物 Antimycobacterial agent-44-nitro-N-[4-(2-pyridyl)thiazol-2-yl]benzamid
Antimycobacterial agent-4 (4-nitro-N-[4-(2-pyridyl)thiazol-2-yl]benzamide) has antibacterial activity against Mycobacterium tuberculosis.
价 格：￥电议型 号：T60073产 地：中国大陆
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T60072ZL0590；化合物ZL0590ZL0590
ZL0590 is an effective and selective inhibitor of BD1-BRD4 (IC50 = 90 nM) with anti-inflammatory activities.
价 格：￥电议型 号：T60072产 地：中国大陆
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T60071PF 00356231；化合物PF 00356231PF 00356231
PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).
价 格：￥电议型 号：T60071产 地：中国大陆
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T6007Birinapant比瑞那帕TL32711|||比瑞那帕
Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with potential antineoplastic activity.
价 格：￥电议型 号：T6007产 地：中国大陆
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T60067WAY-297174；化合物WAY-297174WAY-297174
WAY-297174 is a human protein kinase CK2 inhibitor with IC50 of > 33 μM.
价 格：￥电议型 号：T60067产 地：中国大陆
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T60065WAY-118959-A；化合物WAY-118959-AWAY-118959-A
WAY-118959-A is a potential microtubule acetylation inhibitor.
价 格：￥电议型 号：T60065产 地：中国大陆
