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  • T6277DoramapimodBIRB 796；达马莫德；度马莫德

    Doramapimod is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.

    价 格：￥电议型 号：T6277产 地：中国大陆

  • T6276KU-57788NU7441

    NU7441 (KU-57788) is a highly effective and specific DNA-PK inhibitor (IC50: 14 nM).

    价 格：￥电议型 号：T6276产 地：中国大陆

  • T6275Obatoclax MesylateObatoclax；GX15-070；奥巴克拉盐酸盐

    Obatoclax is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3.

    价 格：￥电议型 号：T6275产 地：中国大陆

  • T6274RO4929097RG-4733

    RO4929097, a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).

    价 格：￥电议型 号：T6274产 地：中国大陆

  • T6273Vadimezan伐地美生；ASA-404；NSC 640488；5,6-Dimethylxanthenone-4-acetic Acid；DMXAA

    Vadimezan is a fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity. Vadimezan induces the cytokines tumor necrosis alpha (TNF-alpha), serotonin and nitric oxide, resulting in hemorrhagic necrosis and a decrease in angiog

    价 格：￥电议型 号：T6273产 地：中国大陆

  • T6272Fosbretabulin DisodiumCA 4DP；Combretastatin A4 disodium phosphate；CA 4P；Fosbretabulin (Combretastati

    Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium, a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM). Fosbretabulin Disodium inhibits the polymerization of tubulin (IC50: 2.4 μ

    价 格：￥电议型 号：T6272产 地：中国大陆

  • T6271TipifarnibZarnestra；IND 58359；R115777；替吡法尼

    Tipifarnib is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnesylation) for signal transduction. By inhibiting

    价 格：￥电议型 号：T6271产 地：中国大陆

  • T6270Trichostatin A曲古柳菌素A；曲古抑菌素A；TSA

    Trichostatin A is a natural derivative of dienohydroxamic acid isolated from species of the bacterial genus Streptomyces. Trichostatin A (TSA) reversibly and specifically inhibits histone deacetylases, resulting in hyperacetylation of core histones which

    价 格：￥电议型 号：T6270产 地：中国大陆

  • T6269BemcentinibBGB324；R428

    R428 is a selective inhibitor of Axl (IC50: 14 nM) and has been investigated for the treatment of NSCLC.

    价 格：￥电议型 号：T6269产 地：中国大陆

  • T6268Ceftiofur hydrochlorideU-67279A；Excenel hydrochloride；Ceftiofur HCl；头孢噻呋盐酸盐

    Ceftiofur Hydrochloride is the hydrochloride salt form of ceftiofur, a semisynthetic, beta-lactamase-stable, broad-spectrum, third-generation cephalosporin with antibacterial activity.

    价 格：￥电议型 号：T6268产 地：中国大陆

  • T6267Lomitapide洛美他派；AEGR-733；BMS-201038

    Lomitapide is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring triglycerides onto apolipoprotein B (apo-B) i

    价 格：￥电议型 号：T6267产 地：中国大陆

  • T6266PP2AG 1879,AGL 1879；AGL 1879

    PP2 is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.

    价 格：￥电议型 号：T6266产 地：中国大陆

  • T6265Bosentan (hydrate)波生坦水合物；Bosentan Hydrate；Actelion；Benzenesulfonamide；Ro 47-0203

    Bosentan is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.

    价 格：￥电议型 号：T6265产 地：中国大陆

  • T6264Bosentan波生坦；Ro 47-0203；Benzenesulfonamide；Actelion

    Bosentan is a sulfonamide-derived, competitive and specific endothelin receptor antagonist with a slightly higher affinity for the endothelin A receptor than endothelin B receptor. Bosentan blocks the action of endothelin 1, an extremely potent endogenous

    价 格：￥电议型 号：T6264产 地：中国大陆

  • T6263Safflower-yellow

    Safflower yellow is extracted from the flowers of the plant safflower (Carthamus tinctorius) and as the traditional Chinese medicine it has been extensively used for the treatment of cardio cerebrovascular diseases.

    价 格：￥电议型 号：T6263产 地：中国大陆

  • T6262EvacetrapibLY2484595

    Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3.

    价 格：￥电议型 号：T6262产 地：中国大陆

  • T6261CP-466722CP466722；CP 466722

    CP-466722, an effective and reversible ATM inhibitor, does not inhibit ATR and PI3K or PIKK family members in cells.

    价 格：￥电议型 号：T6261产 地：中国大陆

  • T6260AMG-208AMG 208；AMG208

    AMG 208 is a highly selective c-Met inhibitor with IC50 of 9 nM. Phase 1.

    价 格：￥电议型 号：T6260产 地：中国大陆

  • T6259DizocilpineMK-801；地佐环平

    MK-801 (Dizocilpine) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM.

    价 格：￥电议型 号：T6259产 地：中国大陆

  • T6258ZibotentanZD4054

    Zibotentan (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.

    价 格：￥电议型 号：T6258产 地：中国大陆

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