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  • T75924APETx2 TFA；化合物 APETx2 TFAAPETx2 TFA

    APETx2 TFA, a selective and reversible inhibitor of the ASIC3 channel derived from the sea anemone Anthopleura elegantissima, exhibits an IC50 of 63 nM. It operates by directly acting on the external side of the ASIC3 channel. Additionally, APETx2 has been shown to reverse acid-induced and inflammatory pain, as documented in studies [1] [2].

    价 格：￥电议型 号：T75924产 地：中国大陆

  • T75907Ac-RYYRIK-NH2 TFA；化合物 Ac-RYYRIK-NH2 TFAAc-RYYRIK-NH2 TFA

    Ac-RYYRIK-NH2 TFA acts as both a potent partial agonist for ORL1 when transfected in CHO cells (K d = 1.5 nM) and an endogenous ligand of ORL1. Moreover, it serves as a specific antagonist that inhibits G protein activation and competitively blocks the stimulation of [35S]-GTPγS binding to G proteins by nociceptin/orphanin FQ (noc/OFQ) in rat brain membranes and sections [1].

    价 格：￥电议型 号：T75907产 地：中国大陆

  • T75883Agitoxin-2 TFA；化合物 Agitoxin-2 TFAAgitoxin-2 TFA

    Agitoxin-2 TFA, a potent inhibitor of K+ channels, exhibits IC50 values of 201 pM and 144 pM for mK V 1.3 and mK V 1.1, respectively [1] [2].

    价 格：￥电议型 号：T75883产 地：中国大陆

  • T75861ANQ-11125 TFA；化合物 ANQ-11125 TFAANQ-11125 TFA

    ANQ-11125 TFA is a potent, selective motilin antagonist, exhibiting a pKd of 8.24. It effectively inhibits motilide-induced contractions in rabbit models, as demonstrated in vitro [1] [2].

    价 格：￥电议型 号：T75861产 地：中国大陆

  • T75841Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA；化合物 Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFAAc-Tyr(PO3H2)-Glu-Glu-I

    Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA (compound 1) serves as a high-affinity pentapeptide that binds to the src SH2 domain with an IC 50 value of approximately 1 ?M. Additionally, it acts as an inhibitor of src SH3-SH2: phosphoprotein interactions [1].

    价 格：￥电议型 号：T75841产 地：中国大陆

  • T75834Antagonist G TFA；化合物 Antagonist G TFAAntagonist G TFA

    Antagonist G TFA is a potent antagonist of vasopressin, with additional, weaker antagonistic effects on GRP and Bradykinin. This compound also promotes AP-1 transcription and enhances cellular sensitivity to chemotherapy [1] [2].

    价 格：￥电议型 号：T75834产 地：中国大陆

  • T75813Ac9-25 TFA；化合物 Ac9-25 TFAAc9-25 TFA

    Ac9-25 TFA, an N-terminal peptide of Annexin I, functions as a formyl peptide receptor (FPR) agonist, activating neutrophil NADPH oxidase via FPR [1] [2].

    价 格：￥电议型 号：T75813产 地：中国大陆

  • T75810AKTide-2T TFA；化合物 AKTide-2T TFAAKTide-2T TFA

    AKTide-2T TFA, serving as an optimal in vitro substrate for AKT, demonstrates competitive inhibition of histone H2B phosphorylation with a Ki value of 12 nM. It effectively mimics the optimal phosphorylation sequence of Akt and acts as an inhibitory peptide, distinct from the wildtype AKTide due to the absence of Thr at the S22 position [1].

    价 格：￥电议型 号：T75810产 地：中国大陆

  • T75805Antisauvagine-30 TFA；化合物 Antisauvagine-30 TFAAntisauvagine-30 TFA

    Antisauvagine-30 TFA (aSvg-30 TFA), a potent peptidic antagonist specific to the CRF 2 receptor, demonstrates high selectivity and competitive interaction. It shows dissociation constants (Kd) of 1.4 nM for mCRFR2β and 150 nM for CRFR1, highlighting its efficacy [1] [2] [3] [4].

    价 格：￥电议型 号：T75805产 地：中国大陆

  • T75800Ac2-26 TFA；化合物 Ac2-26 TFAAc2-26 TFA

    Ac2-26 TFA, the active N-terminal peptide of Annexin A1 (AnxA1), mitigates ischemia-reperfusion-induced acute lung injury, reduces AnxA1 protein expression, and inhibits the activation of NF-κB and MAPK pathways in affected lung tissue [1].

    价 格：￥电议型 号：T75800产 地：中国大陆

  • T75794Acetyl-Calpastatin(184-210)(human) TFA；化合物 Acetyl-Calpastatin(184-210)(human) TFAAcetyl-Calpastatin(

    Acetyl-Calpastatin(184-210)(human) TFA, a potent, selective, and reversible inhibitor of calpain, demonstrates Ki values of 0.2 nM for ?-calpain and 6 μM for cathepsin L, indicating high specificity and efficacy in inhibiting these enzymes [1] [2].

    价 格：￥电议型 号：T75794产 地：中国大陆

  • T75787Amylin, amide, human TFA；化合物 Amylin, amide, human TFAAmylin, amide, human TFA

    Amylin, amide, human TFA, a 37-amino acid polypeptide, functions as a pancreatic hormone that is cosecreted with insulin, playing distinct roles in metabolism and glucose homeostasis. It regulates blood sugar by inhibiting glucagon secretion, delaying gastric emptying, and promoting satiety [1].

    价 格：￥电议型 号：T75787产 地：中国大陆

  • T75785Apelin-17(human, bovine) TFA；化合物 Apelin-17(human, bovine) TFAApelin-17(human, bovine) TFA

    Apelin-17(human, bovine) TFA is an endogenous agonist of the orphan G protein-coupled receptor APJ. This compound demonstrates affinity for human APJ receptors on HEK 293 cells, evidenced by a pIC50 value of 9.02. Additionally, Apelin-17(human, bovine) TFA has been shown to block the entry of certain HIV-1 and HIV-2 strains into NP2/CD4 cells that express the APJ receptor [1] [2] [3].

    价 格：￥电议型 号：T75785产 地：中国大陆

  • T75784Apelin-36(rat, mouse) TFA；化合物 Apelin-36(rat, mouse) TFAApelin-36(rat, mouse) TFA

    Apelin-36(rat, mouse) TFA, an endogenous agonist for the orphan G protein-coupled receptor APJ, exhibits a strong affinity for APJ receptors with an IC 50 of 5.4 nM and effectively inhibits cAMP production with an EC 50 of 0.52 nM. Moreover, it obstructs the invasion of certain HIV-1 and HIV-2 strains into NP-2/CD4 cells that express the APJ receptor [1] [2].

    价 格：￥电议型 号：T75784产 地：中国大陆

  • T75783Apelin-36(human) TFA；化合物 Apelin-36(human) TFAApelin-36(human) TFA

    Apelin-36(human) TFA, an endogenous agonist of the orphan G protein-coupled receptor APJ, exhibits a potent EC50 of 20 nM and high affinity (pIC5 50 = 8.61) for human APJ receptors in HEK 293 cells. It is involved in significant cardiovascular and metabolic activities. Furthermore, Apelin-36(human) TFA can inhibit the entry of certain HIV-1 and HIV-2 strains into NP2/CD4 cells expressing the APJ receptor. [1] [2] [3] [4]

    价 格：￥电议型 号：T75783产 地：中国大陆

  • T75746Apamin TFA；化合物 Apamin TFAApamin TFA

    Apamin TFA, also known as Apamine TFA, is an 18-amino acid peptide neurotoxin derived from apitoxin (bee venom). It functions as a specifically selective blocker of Ca2+-activated K+ (SK) channels and demonstrates anti-inflammatory and anti-fibrotic activity [1].

    价 格：￥电议型 号：T75746产 地：中国大陆

  • T75736Autocamtide-2-related inhibitory peptide TFA；化合物 Autocamtide-2-related inhibitory peptide TFAAutocam

    Autocamtide-2-related inhibitory peptide (TFA) acts as a highly specific and potent CaMKII inhibitor, exhibiting an IC50 value of 40 nM.

    价 格：￥电议型 号：T75736产 地：中国大陆

  • T75721ATI-2341 TFA；化合物 ATI-2341 TFAATI-2341 TFA

    ATI-2341 is a potent, functionally selective allosteric agonist of the C-X-C chemokine receptor type 4 (CXCR4), acting as a biased ligand that prefers Gαi activation over Gα13. This compound activates the inhibitory heterotrimeric G protein (Gi), leading to reduced cAMP production and enhanced calcium mobilization. ATI-2341 effectively mobilizes bone marrow polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs) [1] [2].

    价 格：￥电议型 号：T75721产 地：中国大陆

  • T75719Akt/SKG Substrate Peptide TFA；化合物 Akt/SKG Substrate Peptide TFAAkt/SKG Substrate Peptide TFA

    Akt/SKG Substrate Peptide TFA is a synthetic peptide designed as a substrate specifically for Akt/PKB and is not phosphorylated by p70S6K or MAPK1 [1].

    价 格：￥电议型 号：T75719产 地：中国大陆

  • T75706Ac-DEVD-CMK TFA；化合物 Ac-DEVD-CMK TFAAc-DEVD-CMK TFA

    Ac-DEVD-CMK (Caspase-3 Inhibitor III) TFA is a selective and irreversible inhibitor of caspase-3, effectively preventing apoptosis triggered by elevated glucose levels or 3,20-dibenzoate (IDB). It is applicable in diverse experimental settings to impede apoptosis, as supported by references [1] [2] [3].

    价 格：￥电议型 号：T75706产 地：中国大陆

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