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TP2015LHS 014 acetate(207678-81-7 free base)HS 014 acetate(207678 81 7 free base),HS 014 acetate(207678817
HS 014 acetate is a potent and selective melanocortin MC4 receptor antagonist (Ki values are 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake in rats and nociception in mice following central administration in vivo. Also inhibits IL-1β-induced Fos expression in the paraventricular hypothalamus.
价 格:¥电议型 号:TP2015L产 地:中国大陆
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TP1925LtcY-NH2 TFA(327177-34-4 free base)tcY-NH-2 TFA(327177-34-4 free base),tcY NH2 TFA(327177 34 4 free b
tcY-NH2 TFA is a selective PAR4 antagonist peptide. Inhibits endostatin release and platelet aggregation induced by thrombin.
价 格:¥电议型 号:TP1925L产 地:中国大陆
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T6362Domatinostat4SC-202;4SC-202 (free base);4SC 202;4SC202
4SC-202 is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. Also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). Phase 1.
价 格:¥电议型 号:T6362产 地:中国大陆
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T6326BMS-345541BMS345541;IKK Inhibitor III;BMS 345541;BMS-345541 free base
BMS-345541 is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.
价 格:¥电议型 号:T6326产 地:中国大陆
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T6303LCCT128930 hydrochlorideCCT128930 hydrochloride(885499-61-6 Free base)
CCT128930 hydrochloride is a potent and selective inhibitor of AKT with IC50 of 6 nM. CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. CCT128930 hydrochloride has 28-fold selectivity over the closely related PKA kinase (IC50:
价 格:¥电议型 号:T6303L产 地:中国大陆
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T6294NVP-BSK805 2HCl (1092499-93-8(free base))BSK 805
NVP-BSK805 2HCl(IC50=0.5 nM), a specific and effective ATP-competitive JAK2 inhibitor, is more than 20-fold specificity over JAK1, JAK3 and TYK2.
价 格:¥电议型 号:T6294产 地:中国大陆
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T6159LY-2584702 free base
LY2584702 is a selective, ATP-competitive p70S6K inhibitor(IC50: 4 nM).
价 格:¥电议型 号:T6159产 地:中国大陆
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T6140SB-334867 free baseSB334867A free base;SB334867;SB 334867;SB-334867
SB-334867 is a selective orexin-1 (OX1) receptor antagonist.
价 格:¥电议型 号:T6140产 地:中国大陆
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T6072LBGT226BGT226 free base;NVP-BGT226
Bgt226 is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.
价 格:¥电议型 号:T6072L产 地:中国大陆
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T5862Ezatiostat TFAEzatiostat;Ezatiostat TFA (free base);TLK199;TER199(free base)
Ezatiostat is a liposomal small-molecule glutathione analog inhibitor of glutathione S-transferase (GST) P1-1 with hematopoiesis-stimulating activity.
价 格:¥电议型 号:T5862产 地:中国大陆
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T5677SAR125884 hydrochlorid (1116743-46-4(free base))
SAR125844 is a potent and selective MET kinase inhibitor with a favorable preclinical toxicity profile,(IC50=4.2 nM).
价 格:¥电议型 号:T5677产 地:中国大陆
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T5465PF-5274857PF5274857;PF-5274857 freebase;PF 5274857
PF-5274857 is an effective and selective hedgehog signaling pathway inhibitor (IC50: 5.8 nM and a Ki: 4.6 nM). PF-5274857 is a potentially attractive clinical candidate for the treatment of tumor types including brain tumors and brain metastasis driven by
价 格:¥电议型 号:T5465产 地:中国大陆
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T5437Gefitinib-based PROTAC 3
Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a VHL ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectively[1].
价 格:¥电议型 号:T5437产 地:中国大陆
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T5164Cabozantinib hydrochlorideCabozantinib hydrochloride (849217-68-1(free base));BMS-907351;XL184;盐酸卡博替
Cabozantinib (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM).
价 格:¥电议型 号:T5164产 地:中国大陆
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T5162MRT67307 HCl (1190378-57-4(free base))盐酸MRT67307
MRT67307 is a kinase inhibitor of TBK1, MARK1-4, IKKε, and NUAK1 (IC50: 19, 27-52, 160, and 230 nM, respectively).
价 格:¥电议型 号:T5162产 地:中国大陆
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T5148Atosiban acetate (90779-69-4 free base)RWJ22164;RW22164;Atosiban acetate;醋酸阿托西班
Atosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Atosiban inhibits the oxytocin-mediated release of inositol trisphosphate from the myome
价 格:¥电议型 号:T5148产 地:中国大陆
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T5146Eptifibatide acetate (148031-34-9 free base)依菲巴特醋酸盐;Eptifibatide acetate
Eptifibatide, an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class, is a cyclic heptapeptide constructed from 6 amino acids and a mercaptopropionyl residue.
价 格:¥电议型 号:T5146产 地:中国大陆
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T5145Oxytocin acetate (50-56-6 free base)Oxytocin acetate;α-Hypophamine acetate;Oxytocic hormone acetate;
Oxytocin is a mammalian neurohypophysial hormone, a ligand of oxytocin receptor.
价 格:¥电议型 号:T5145产 地:中国大陆
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T5144Desmopressin acetate (16679-58-6 free base)醋酸去氨加压素;DDAVP;Desmopressin acetate
Desmopressin is the synthetic analog of the antidiuretic hormone arginine vasopressin. Vasopressin Receptor The antidiuretic properties of desmopressin have led to its use in polyuric conditions including primary nocturnal enuresis, nocturia, and diabetes
价 格:¥电议型 号:T5144产 地:中国大陆
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T5140WDR5-0103 hydrochloride[890190-22-4(free base)]WD-Repeat Protein 5-0103;WDR5-0103盐酸盐
WDR5-0103 is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist (Kd: 450 nM).
价 格:¥电议型 号:T5140产 地:中国大陆