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T6249Avagacestat；化合物AvagacestatBMS-708163；BMS-708163
Avagacestat (BMS-708163) (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.
价 格：￥电议型 号：T6249产 地：中国大陆
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T6229Daclatasvir达拉他韦Daklinza|||达卡他韦|||EBP 883|||达拉他韦|||BMS-790052
Daclatasvir (EBP 883) (BMS-790052) is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture. Phase 3.
价 格：￥电议型 号：T6229产 地：中国大陆
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T6203LSaxagliptin hydrochloride化合物 T6203LBMS477118|||Saxagliptin|||BMS 477118|||Saxagliptin HCl|||BMS-4771
Saxagliptin is a new oral hypoglycemic of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Saxagliptin is a competitive DPP4 inhibitor that slows the inactivation of the incretin hormones and reducing fasting and postprandial glucose concentrations in a glucose-dependent manner in patients with type 2 diabetes mellitus.
价 格：￥电议型 号：T6203L产 地：中国大陆
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T6203Saxagliptin；沙格列汀BMS-477118|||Onglyza；BMS-477118|||沙克列汀|||Onglyza|||沙格列汀
Saxagliptin (BMS-477118) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.
价 格：￥电议型 号：T6203产 地：中国大陆
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T6049SNS-032；化合物SNS032SNS032|||BMS-387032；SNS032|||BMS-387032
SNS-032 (BMS-387032) is a selective inhibitor of CDK2 (IC50: 48 nM ) and is 10- and 20-fold selective over CDK1/CDK4. It is also sensitive to CDK7/9 (IC50: 62 nM/4 nM), and no effect on CDK6.
价 格：￥电议型 号：T6049产 地：中国大陆
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T6036Brivanib；布立尼布BMS-540215；BMS-540215|||布立尼布
Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β. Phase 3.
价 格：￥电议型 号：T6036产 地：中国大陆
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T60052BMS-905；化合物BMS-905BMS-905
BMS-905 is a potent dual inhibitors of TLR7 and TLR8 with good selectivity against TLR9 and other family members. BMS-905 can be used in studies about the treatment of diseases such as psoriasis, arthritis, and lupus.
价 格：￥电议型 号：T60052产 地：中国大陆
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T5697BMS-1166；化合物BMS1166BMS-1166
BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.
价 格：￥电议型 号：T5697产 地：中国大陆
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T5532BMS-687453；化合物BMS-687453BMS-687453|||PPAR|||BMS687453|||Peroxisome proliferator-activated receptors|
BMS-687453 is a potent and selective PPAR alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma in PPAR-GAL4 transactivation assays.
价 格：￥电议型 号：T5532产 地：中国大陆
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T5407Branebrutinib；化合物BMS-986195BMS986195；BMS986195
Branebrutinib (BMS986195) is a potent, covalent inhibitor of Bruton´s tyrosine kinase (BTK), >5,000-fold selective over all kinases outside of the Tec family (IC50 <1 nM for BTK).
价 格：￥电议型 号：T5407产 地：中国大陆
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T5398BMS 599626 2HCl (873837-23-1(HCl))；化合物BMS 599626 2HClAC480 dihydrochloride；AC480 dihydrochloride
BMS 599626 2HCl (873837-23-1(HCl)) (AC480 dihydrochloride) is a selective inhibitor of HER1 and HER2 (IC50s: 20 nM and 30 nM), ~8-fold less potent to HER4, >100-fold to Lck, VEGFR2, c-Kit, MET, etc.
价 格：￥电议型 号：T5398产 地：中国大陆
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T5390BMS-599626 Hydrochloride；BMS-599626盐酸盐AC480 Hydrochloride；AC480 Hydrochloride
BMS-599626 Hydrochloride (AC480 Hydrochloride) is an orally bioavailable inhibitor of the HER1, HER2 and HER4 tyrosine kinases (IC50 =22, 32 and 190 nM, respectively) with potential antineoplastic activity. BMS-599626 Hydrochloride inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors.
价 格：￥电议型 号：T5390产 地：中国大陆
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T5164Cabozantinib hydrochloride；盐酸卡博替尼XL184|||Cabozantinib hydrochloride (849217-68-1(free base))|||BMS-9
Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM).
价 格：￥电议型 号：T5164产 地：中国大陆
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T5138BMS-986142；化合物BMS-986142BMS-986142
BMS-986142 is a potent and highly selective reversible BTK inhibitor (IC50: 0.5 nM).
价 格：￥电议型 号：T5138产 地：中国大陆
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T4696BMS202 hydrochloride (1675203-84-5(free base))；化合物BMS202 hydrochloridePD-1/PD-L1 inhibitor 2 hydroch
BMS202 hydrochloride (1675203-84-5(free base)) (PD-1/PD-L1 inhibitor 2 hydrochloride) is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L1. Binding of BMS202 promotes PD-L1 dimerisation and blocks the PD-L1/ PD1 interaction.
价 格：￥电议型 号：T4696产 地：中国大陆
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T4665Temsavir；化合物BMS626529BMS626529；BMS626529
Temsavir (BMS626529) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.
价 格：￥电议型 号：T4665产 地：中国大陆
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T4654(±)-Ibipinabant；化合物SLV319(±)-BMS6462|||SLV319|||(±)-SLV319；(±)-BMS6462|||SLV319|||(±)-SLV319
(±)-Ibipinabant ((±)-SLV319) has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes.
价 格：￥电议型 号：T4654产 地：中国大陆
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T4600BMS-3；化合物BMS3BMS-3
BMS-3 is a potent LIMK inhibitor with IC50s of 5 nM and 6 nM for LIMK1 and LIMK2, respectively.
价 格：￥电议型 号：T4600产 地：中国大陆
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T4598BMS-5；化合物BMS5BMS5|||LIMKi 3；BMS5|||LIMKi 3
BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively.
价 格：￥电议型 号：T4598产 地：中国大陆
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T4584BMS-813160；化合物BMS813160BMS 813160；BMS 813160
BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular.
价 格：￥电议型 号：T4584产 地：中国大陆
