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T62063Antibacterial agent 76;化合物 Antibacterial agent 76Antibacterial agent 76
Antibacterial agent 76 (compound 9) is a potent antibacterial agent.
价 格:¥电议型 号:T62063产 地:中国大陆
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T61911Antibacterial agent 98;化合物 Antibacterial agent 98Antibacterial agent 98
Antibacterial agent 98 (compound g37) is an effective oral antibacterial agent, which can inhibit the ATPase activity of Gyrase B and weaken the DNA super-helix of S. aureus. Antibacterial agent 98 does not induce the development of MRSA (methicillin-resistant Staphylococcus aureus) resistance.
价 格:¥电议型 号:T61911产 地:中国大陆
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T61853Antimycobacterial agent-1;化合物 Antimycobacterial agent-1Antimycobacterial agent-1
Antimycobacterial agent-1 (compound 33) demonstrates potent antimycobacterial activity against Mycobacterium tuberculosis H37Ra, with a minimal inhibitory concentration (MIC) value of 1 μg/ml. Notably, antimycobacterial agent-1 exhibits low cytotoxicity in normal cells, as evidenced by an IC50 value of 143.2 μg/ml in Vero cells [1].
价 格:¥电议型 号:T61853产 地:中国大陆
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T61799Antibacterial agent 75;化合物 Antibacterial agent 75Antibacterial agent 75
Antibacterial agent 75 (compound 24) possesses antibacterial properties. Its notable attribute is the ability to re-sensitize VRSA (Vancomycin-Resistant Staphylococcus aureus) strains to vancomycin, as reported in reference [1].
价 格:¥电议型 号:T61799产 地:中国大陆
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T61665Antibacterial agent 118;化合物 Antibacterial agent 118Antibacterial agent 118
Antibacterial agent 118 (also known as compound 20) is a potent antimycobacterial compound with activity against various mycobacterial strains, including Mtb H37Ra, M. aurum, M. smegmatis, Mtb H37Rv, and M. avium. The minimum inhibitory concentration (MIC) values for Antibacterial agent 118 against these strains are 40.7 μM, 10.2 μM, 163.0 μM, 62.5 μM, and 62.5 μM, respectively. This compound holds potential for tuberculosis research [1].
价 格:¥电议型 号:T61665产 地:中国大陆
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T61640Antibacterial agent 77;化合物 Antibacterial agent 77Antibacterial agent 77
Antibacterial agent 77 (compound 12) is an antibacterial agent [1].
价 格:¥电议型 号:T61640产 地:中国大陆
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T61624Antibacterial agent 106;化合物 Antibacterial agent 106Antibacterial agent 106
Antibacterial agent 106 (compound 8) is a highly effective orally active antibacterial compound with antibiofilm activity. It demonstrates potent antibacterial effects against multi-drug resistant (MDR)-Gram-positive pathogens, including the eradication of 99.7% of intracellular methicillin-resistant S. aureus (MRSA) harbored within macrophages [1].
价 格:¥电议型 号:T61624产 地:中国大陆
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T61284Antibacterial agent 94;化合物 Antibacterial agent 94Antibacterial agent 94
Antibacterial agent 94 (compound 5b) is a highly effective antibacterial agent that demonstrates strong activity against various bacterial strains. Notably, Antibacterial Agent 94 is capable of eradicating MRSA persisters, highlighting its potential as a therapeutic solution. Its mechanism of action involves interference with the bacterial membrane and disruption of the phosphatidylglycerol (PG) synthesis pathway [1].
价 格:¥电议型 号:T61284产 地:中国大陆
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T61251Antibacterial agent 97;化合物 Antibacterial agent 97Antibacterial agent 97
Antibacterial Agent 97, a potent hit compound, exhibits antibacterial activity, demonstrating minimum inhibitory concentrations (MIC) of 16 μg/mL against both Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) [1].
价 格:¥电议型 号:T61251产 地:中国大陆
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T61170Antibacterial agent 96;化合物 Antibacterial agent 96Antibacterial agent 96
Antibacterial Agent 96 (Compound 4k) is a potent antibacterial and antitubercular compound effective against both drug-susceptible and multidrug-resistant Mycobacterium tuberculosis (M. tuberculosis) strains. However, it exhibits toxicity to HepG2 and Vero cells [1].
价 格:¥电议型 号:T61170产 地:中国大陆
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T61159Antibacterial agent 26;抗菌剂26Antibacterial agent 26
Antibacterial agent 26 is an antimicrobial compound that is a potent DHFR inhibitor (S. aureus DHFR Ki of 0.020 nM).
价 格:¥电议型 号:T61159产 地:中国大陆
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T61149Antibacterial agent 121;化合物 Antibacterial agent 121Antibacterial agent 121
Antibacterial agent 121 (Compound 10) demonstrates antibacterial properties and exhibits efficacy against mycobacterial strains while also possessing anti-inflammatory activity. This compound finds potential applications in Tuberculosis (TB) research [1].
价 格:¥电议型 号:T61149产 地:中国大陆
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T61126Antibacterial synergist 1;化合物 Antibacterial synergist 1Antibacterial synergist 1
Antibacterial synergist 1 (compound 20P) is a potent inhibitor of bacterial biofilm formation. It effectively suppresses the production of pyocyanin, with an IC 50 of 8.6 μM, and inhibits biofilm formation with an IC 50 of 4.5 μM. Antibacterial synergist 1 shows promise in the research of P. aeruginosa infections [1].
价 格:¥电议型 号:T61126产 地:中国大陆
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T61123Antibacterial agent 111;化合物 Antibacterial agent 111Antibacterial agent 111
Antibacterial agent 111 (Compound 3) exhibits potent antibacterial activity against B. cereus and K. pneumonia, with MIC values of 3.90 μg/mL and 0.49 μg/mL, respectively. It achieves this antibacterial effect by strongly binding to specific residues of tyrosyl-tRNA synthetase [1].
价 格:¥电议型 号:T61123产 地:中国大陆
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T61104Antibacterial agent 82;化合物 Antibacterial agent 82Antibacterial agent 82
Antibacterial agent 82 (compound 7p) is an antibacterial agent [1].
价 格:¥电议型 号:T61104产 地:中国大陆
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T61096Antibacterial agent 95;化合物 Antibacterial agent 95Antibacterial agent 95
Antibacterial agent 95 (2-(quinoline-4-methoxy) acetamide), a new antituberculotic agent, exhibited a minimum inhibitory concentration (MIC) of only 0.3 μM against the reference strain of Mycobacterium tuberculosis H37Rv. Additionally, it effectively suppressed the growth of Mycobacterium tuberculosis in the macrophage model of tuberculosis infection.
价 格:¥电议型 号:T61096产 地:中国大陆
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T60865Antibacterial agent 78;化合物 Antibacterial agent 78Antibacterial agent 78
Antibacterial agent 78 (compound 30) is an antibacterial agent with improved cytotoxicity profile[1].
价 格:¥电议型 号:T60865产 地:中国大陆
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T60804Antibacterial agent 114;化合物 Antibacterial agent 114Antibacterial agent 114
Antibacterial agent 114 (compound 1) is a potent antibacterial agent with MIC values of 625, 625, 625, 625, 625, 1250 and 1250 μM for P.aeruginosa, B.subtilis, E.coli, E.faecalis, S.typhimuriumand, S.mutans, and S.aureus microorganisms, respectively [1].
价 格:¥电议型 号:T60804产 地:中国大陆
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T60690Antibacterial agent 122;化合物 Antibacterial agent 122Antibacterial agent 122
Antibacterial agent 122 (compound 15) is a thiourea derivative that can be used in the studies of tuberculosis. Antibacterial agent 122 shows low cytotoxicity as well as anti-mycobacterial activity [1].
价 格:¥电议型 号:T60690产 地:中国大陆
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T60666Antibacterial agent 105;化合物 Antibacterial agent 105Antibacterial agent 105
Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones. Antibacterial agent 105 exhibits antibacterial activity against M. tuberculosis with MIC 90 of 2.64 μM. Moreover, Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC 90 s of 11.18, 11.18,0.70,1.40,44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum, BCG, E. aerogenes and S. aureus, respectively [1].
价 格:¥电议型 号:T60666产 地:中国大陆