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T81054T-1-MCPAB;化合物 T-1-MCPABT-1-MCPAB
T-1-MCPAB, a VEGFR-2 inhibitor with an IC50 of 0.135 ?M, effectively suppresses MCF7 cell migration and has applications in cancer research [1].
价 格:¥电议型 号:T81054产 地:中国大陆
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T80531Ac-AAVALLPAVLLALLAP-DEVD-CHO;化合物 Ac-AAVALLPAVLLALLAP-DEVD-CHODEVD-CHO-CPP 32;DEVD-CHO-CPP 32
Ac-AAVALLPAVLLALLAP-DEVD-CHO (DEVD-CHO-CPP 32) serves as a potent and reversible inhibitor of caspase-3 [1].
价 格:¥电议型 号:T80531产 地:中国大陆
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T80282cPcAMP1/26;化合物 cPcAMP1/26cPcAMP1/26
cPcAMP1/26, an antimicrobial peptide, exhibits potent bactericidal activity against A. hydrophila and S. aureus by inducing depolarization of the bacterial plasma membrane and elevating intracellular ROS (Reactive Oxygen Species) levels [1].
价 格:¥电议型 号:T80282产 地:中国大陆
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T79693PIMPC;化合物 PIMPCPIMPC
PIMPC, a compound endowed with antioxidant and metal-chelating properties, acts as a novel inhibitor of glycogen synthase kinase 3 (GSK-3), and exhibits potential therapeutic effects for Alzheimer´s disease [1].
价 格:¥电议型 号:T79693产 地:中国大陆
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T79304Semapimod;化合物 SemapimodCPSI-2364|||CNI-1493 free base;CPSI-2364|||CNI-1493 free base
Semapimod is an inhibitor of proinflammatory cytokine production, capable of suppressing TNF-α, IL-1β, and IL-6. It hinders TLR4 signaling with an IC50 of approximately 0.3 μM, impedes p38 MAPK, and reduces nitric oxide production in macrophages. This compound shows promise for treating various inflammatory and autoimmune disorders [1] [2] [3].
价 格:¥电议型 号:T79304产 地:中国大陆
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T78837CP-07;化合物 CP-07CP-07
CP-07 is a selective and effective PROTAC CDK9 degrader (DC50: 43 nM), demonstrating inhibition of 22RV1 cell proliferation (IC50: 62 nM) and colony formation by attenuating levels of Mcl-1 and c-Myc. Additionally, CP-07 has been shown to impede the growth of 22RV1 xenograft tumors and is applicable in prostate cancer research [1].
价 格:¥电议型 号:T78837产 地:中国大陆
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T78605CpCDPK1/TgCDPK1-IN-1;CpCDPK1/TgCDPK1抑制剂1CpCDPK1/TgCDPK1-IN-1
CpCDPK1/TgCDPK1-IN-1 is a potent dual inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infections and cryptosporidiosis.
价 格:¥电议型 号:T78605产 地:中国大陆
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T78569CPT2;化合物 CPT2Carnitine palmitoyltransferase 2;Carnitine palmitoyltransferase 2
Carnitine palmitoyltransferase 2 (CPT2), an enzyme involved in fatty acid oxidation, serves as a prognostic biomarker for colorectal cancer (CRC). Overexpression of CPT2 activates phosphorylated p53, enhancing its expression, which in turn suppresses tumor growth and induces apoptosis. Conversely, a deficiency in CPT2 leads to the prevalent hereditary disorder of long-chain fatty acid oxidation in skeletal muscle. Additionally, the downregulation of CPT2 correlates strongly with the advancement
价 格:¥电议型 号:T78569产 地:中国大陆
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T78419lucPpy-IN-1;化合物 lucPpy-IN-1lucPpy-IN-1
LucPpy-IN-1 (compound 9) is an inhibitor of ATP-dependent luciferase from Photinus pyralis (lucPpy), exhibiting an IC50 value of 4.0 μM. It is utilized in research to assess the druggability [1] of the target enzyme.
价 格:¥电议型 号:T78419产 地:中国大陆
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T7839Lasofoxifene Tartrate;酒石酸拉索昔芬CP-336156;CP-336156|||酒石酸拉索昔芬
Lasofoxifene Tartrate (CP-336156) is a third-generation, non-steroidal selective estrogen receptor modulator.
价 格:¥电议型 号:T7839产 地:中国大陆
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T782284-Chloro-L-phenylalanine;4-氯-L-苯基丙氨酸L-4-Chlorophenylalanine|||L-PCPA;L-4-Chlorophenylalanine|||L-PCP
4-Chloro-L-phenylalanine (L-PCPA) is an inhibitor of 5-HT biosynthesis.4-Chloro-L-phenylalanine is also a non-specific antagonist of tryptophan hydroxylase (TPH1 and TPH2).
价 格:¥电议型 号:T78228产 地:中国大陆
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T78024Selcopintide acetate;化合物 Selcopintide acetateCpne7-DP acetate;Cpne7-DP acetate
Selcopintide acetate (Cpne7-DP), a synthetic peptide, mirrors the 344-353 amino acid sequence of the hCPNE7 protein. It effectively mimics CPNE7´s in vitro activity, enhancing the expression of odontoblast markers like DSPP and Nestin. Selcopintide acetate has been shown to facilitate dentin regeneration across varying levels of dentinal defects, with the regenerated tissue exhibiting true dentin properties [1].
价 格:¥电议型 号:T78024产 地:中国大陆
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T78012CCP peptide TFA;化合物 CCP peptide TFACCP peptide TFA
CCP Peptide TFA, a synthetic cyclic citrullinated peptide, serves as a serological substrate for the detection of anti-CCP antibodies and is a highly specific target for autoantibodies associated with rheumatoid arthritis (RA) [1] [2].
价 格:¥电议型 号:T78012产 地:中国大陆
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T77931PROTAC IRAK3 degrade-1 formic;化合物 PROTAC IRAK3 degrade-1 formicPROTAC IRAK3 degrade-1 formic
PROTAC IRAK3 Degrade-1 (Compound 23) is a selective and potent IRAK3 degrader, demonstrating an IC50 value of 5 nM [1].
价 格:¥电议型 号:T77931产 地:中国大陆
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T77873NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT hydrochloride;化合物 NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT hydroc
Compound I, NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT hydrochloride, is a topoisomerase I inhibitor that demonstrates effective antibody-drug conjugate (ADC) activity both in vivo and in vitro, with delivery to cells facilitated through targeted antibody conjugation [1].
价 格:¥电议型 号:T77873产 地:中国大陆
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T77567BCPA;化合物BCPABCPA
BCPA is a non-cytotoxic Pin1 modulator.BCPA modulates osteoclast activation and attenuates the reduction of Pin1 protein, thereby inhibiting RANKL-induced receptor activators of osteoclastogenesis.BCPA is used in the study of osteoporosis.
价 格:¥电议型 号:T77567产 地:中国大陆
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T77466Tremelimumab;曲美木单抗Ticilimumab|||CP-675206;Ticilimumab|||CP-675206
Tremelimumab is a cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) blocking antibody.Tremelimumab is often used in combination with Durvalumab for the treatment of solid cancers such as hepatocellular carcinoma and lung cancer.
价 格:¥电议型 号:T77466产 地:中国大陆
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T76735Mupadolimab;莫帕利单抗CPI-006;CPI-006
Mupadolimab (CPI-006) is a humanized FC-γR binding deficient IgG1 anti-CD73 antibody with potential anticancer activity and activation of CD73POS B cells.
价 格:¥电议型 号:T76735产 地:中国大陆
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T75913[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic polypeptide TFA;化合物 [cPP1-7,NPY19-23,Ala31,Aib32,Gln
[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide is a potent, selective neuropeptide Y Y5 receptor agonist, demonstrating binding affinity with an IC50 of 0.24 nM for the hY5 receptor. This compound significantly stimulates food intake [1].
价 格:¥电议型 号:T75913产 地:中国大陆
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T75791-BCP;化合物1-BCPPiperonylic acid piperidide;Piperonylic acid piperidide
1-BCP (Piperonylic acid piperidide) is a centrally active drug that modulates AMPA receptor gated currents.
价 格:¥电议型 号:T7579产 地:中国大陆