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T61681CD38 inhibitor 2;化合物 CD38 inhibitor 2CD38 inhibitor 2
CD38 inhibitor 2 is a potent CD38 inhibitor ( IC 50 = 0.01 ~ 0.1 μΜ).
价 格:¥电议型 号:T61681产 地:中国大陆
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T61578BRD3731;化合物 BRD3731BRD3731
BRD3731 is a selective inhibitor of GSK3β, demonstrating an IC50 value of 15 nM for GSK3β and 215 nM for GSK3α. Due to its inhibitory properties, BRD3731 holds promise for investigating various medical conditions, including post-traumatic stress disorder (PTSD), psychiatric disorders, diabetes, and neurodegenerative disorders [1].
价 格:¥电议型 号:T61578产 地:中国大陆
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T6152PD318088;化合物PD318088PD318088
PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binding simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site.
价 格:¥电议型 号:T6152产 地:中国大陆
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T61424OD36 hydrochloride;OD36盐酸盐OD 36 hydrochloride|||OD-36 hydrochloride;OD 36 hydrochloride|||OD-36 hydr
OD36 hydrochloride (OD-36 hydrochloride) is a potent RIPK2 inhibitor with an IC50 of 5.3 nM.OD36 hydrochloride is a macrocyclic inhibitor that binds efficiently to the ATP pocket of the ALK2 kinase and effectively antagonizes mutant ALK2 signaling and osteogenic differentiation.OD36 hydrochloride targets ALK2. OD36 hydrochloride targets ALK2 with a KD of 37 nM.
价 格:¥电议型 号:T61424产 地:中国大陆
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T5S06203-Dehydrotrametenolic acid3-氢化去氢松苓酸Dehydrotrametenolic acid|||松苓新酸|||3-氢化去氢松苓酸
1. 3-Dehydrotrametenolic acid can be a potential anticancer agent against H-ras transformed tumor. 2. Dehydrotrametenolic acid is a promising candidate for a new type of insulin-sensitizing drug.
价 格:¥电议型 号:T5S0620产 地:中国大陆
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T59863-Hydroxypicolinic acid3-羟基-2-吡啶甲酸3-羟基-2-吡啶甲酸|||Picolinic acid, 3-hydroxy- (6CI,7CI,8CI)|||2-Carboxy
3-Hydroxypicolinic acid (Picolinic acid, 3-hydroxy- (6CI,7CI,8CI)), a picolinic acid derivative, belongs to the pyridine family.
价 格:¥电议型 号:T5986产 地:中国大陆
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T58823-Bromopyruvic acid3-溴丙酮酸Hexokinase II Inhibitor II, 3-BP|||3-溴丙酮酸|||Bromopyruvic acid
3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition. It is inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs.
价 格:¥电议型 号:T5882产 地:中国大陆
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T5854AM580;化合物AM580NSC608001|||CD336|||Ro 40-6055;NSC608001|||CD336|||Ro 40-6055
AM580 (CD336) is a retinoic acid receptor agonist that is selective for RARα( IC50 : 8 nM )
价 格:¥电议型 号:T5854产 地:中国大陆
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T55693-Amino-4-methylpentanoic acid3-氨基-4-甲基戊酸DL-Homovaline|||3-氨基-4-甲基戊酸|||DL-beta-leucine|||beta-Aminoi
3-Amino-4-methylpentanoic acid (DL-Homovaline) is a beta-amino acid that is pentanoic acid substituted at positions 3 and 4 by amino and methyl groups respectively. It has a role as a human metabolite.
价 格:¥电议型 号:T5569产 地:中国大陆
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T5463Verdiperstat;化合物AZD3241AZD3241|||AZD 3241;AZD3241|||AZD 3241
Verdiperstat (AZD 3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders.
价 格:¥电议型 号:T5463产 地:中国大陆
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T5409AZD3229;化合物AZD3229AZD3229
AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors. It demonstrates potent single-digit nM growth inhibition across a broad cell panel.
价 格:¥电议型 号:T5409产 地:中国大陆
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T5383D3-βArr;化合物D3-βArrNCGC00379308;NCGC00379308
D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.
价 格:¥电议型 号:T5383产 地:中国大陆
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T5175azd1390;化合物azd1390azd1390|||azd1390|||ATM/ATR|||azd-1390|||ATM and RAD3 related|||AZD 1390|||inhibit
AZD1390 is an exceptionally potent inhibitor of ATM in cells (IC50: 0.78 nM) with >10,000-fold selectivity over closely related members of the PIKK family of enzymes.
价 格:¥电议型 号:T5175产 地:中国大陆
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T49237-Dehydrocholesterol;7-去氢胆固醇Provitamin D3|||7-DHC;Provitamin D3|||7-DHC|||7-去氢胆固醇
7-Dehydrocholesterol (Provitamin D3) down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.
价 格:¥电议型 号:T4923产 地:中国大陆
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T49073,4-Dihydroxybenzeneacetic acid3,4-二羟基苯乙酸DOPAC|||3,4-Dihydroxyphenylacetic acid|||3,4-二羟基苯乙酸
3,4-Dihydroxybenzeneacetic acid (3,4-Dihydroxyphenylacetic acid) is the main metabolite of dopamine.
价 格:¥电议型 号:T4907产 地:中国大陆
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T4892Melilotic acid;化合物 Melilotic acid3-(2-Hydroxyphenyl)propionic acid;3-(2-Hydroxyphenyl)propionic acid
Melilotic acid (3-(2-Hydroxyphenyl)propionic acid), also known as melilotic acid or melilotate. Within the cell, 3-(2-hydroxyphenyl)propanoic acid is primarily located in the cytoplasm. Melilotic acid can be biosynthesized from propionic acid. Outside of the human body, 3-(2-hydroxyphenyl)propanoic acid can be found in a number of food items such as herbs and spices, red beetroot, chinese cinnamon, and bilberry. This makes 3-(2-hydroxyphenyl)propanoic acid a potential biomarker for the consumpti
价 格:¥电议型 号:T4892产 地:中国大陆
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T48873-Amino-2-methylpropanoic acid3-氨基异丁酸DL-3-AMINOISOBUTYRIC ACID|||3-氨基异丁酸|||α-Methyl-β-alanine
3-Amino-2-methylpropanoic acid (α-Methyl-β-alanine) is the product from the conversion of N-carbamyl-beta-aminoisobutyric acid by the enzyme Beta-ureidopropionase (EC 3.5.1.6), the last step in pyrimidine degradation. Beta-ureidopropionase deficiency is an inborn error of pyrimidine degradation associated with neurological abnormalities.
价 格:¥电议型 号:T4887产 地:中国大陆
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T47703-Amino-4-hydroxybenzoic acid3-氨基-4-羟基苯甲酸3-氨基-4-羟基苯甲酸|||3-amino-4-hydroxybenzenecarboxylic acid
3-Amino-4-hydroxybenzoic acid (3-amino-4-hydroxybenzenecarboxylic acid) is a useful research chemical.
价 格:¥电议型 号:T4770产 地:中国大陆
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T4249AZD3759 hydrochloride;化合物AZD3759 hydrochlorideAZD3759 hydrochloride
AZD3759 (hydrochloride) is an effective, orally active and central nervous system-penetrant EGFR inhibitor. At Km ATP concentrations, the IC50s are 0.2/0.3/0.2 nM for EGFR (L858R)/EGFR (wt)/EGFR (exon 19Del).
价 格:¥电议型 号:T4249产 地:中国大陆
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T413553-Methyl-2-quinoxalinecarboxylic acid;化合物 3-Methyl-2-quinoxalinecarboxylic acid3-Methyl-2-quinoxalin
3-Methyl-2-quinoxalinecarboxylic acid has a wide range of applications in life science related research.
价 格:¥电议型 号:T41355产 地:中国大陆