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T382924-(N-Boc-amino)piperidine;4-(N-Boc-amino)piperidine4-(N-Boc-amino)piperidine
4-(N-Boc-amino)piperidine is an organic building block.1,2It has been used in the synthesis of aminopiperidine antiviral chemokine (C-C motif) receptor 5 (CCR5) antagonists and antibacterial agents.
价 格:¥电议型 号:T38292产 地:中国大陆
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T381214-Nitrophenyl β-D-Cellobioside;4-Nitrophenyl β-D-Cellobioside4-Nitrophenyl β-D-Cellobioside
4-Nitrophenyl β-D-cellobioside is a disaccharide and an enzyme substrate. It has been used to characterize the function of endoglucanase 1 from T. harzianum, β-glucosidase from T. xylanolyticum, and glycoside hydrolase family 3 (GH3) aryl β-glucosidases from A. oryzae.
价 格:¥电议型 号:T38121产 地:中国大陆
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T381194-Methylumbelliferyl Caprylate;4-Methylumbelliferyl Caprylate4-Methylumbelliferyl Caprylate
4-Methylumbelliferyl caprylate (MUCAP) is a fluorogenic substrate for C8 esterase. MUCAP is cleaved by C8 esterase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.
价 格:¥电议型 号:T38119产 地:中国大陆
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T38062N-acetyl Leukotriene E4;N-acetyl Leukotriene E4N-acetyl Leukotriene E4;N-acetyl Leukotriene E4
N-acetyl LTE4 is the major inactive metabolite of LTE4 found in bile. This route of metabolism is prominent in the rat, but of minor importance in humans. N-acetyl LTE4 is 100 times less potent than LTC4 as a vasoconstricting agent. In healthy human subjects urinary excretion of N-acetyl LTE4 is about 1.5 nmol/mol creatinine, which is considerably less than that of LTE4 (12 nmol/mol creatinine).
价 格:¥电议型 号:T38062产 地:中国大陆
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T38043Resolvin E4;Resolvin E4Resolvin E4
Resolvin E4 (RvE4) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.1It is produced from eicosapentaenoic acid by 15-lipoxygenase (15-LO)via15(S)-HpEPE and 15S-hydroxy, 5S-HpEPE intermediatesin vitroand by isolated human M2 macrophages or polymorphonuclear (PMN) neutrophils under normoxic or hypoxic conditions. RvE4 synthesis is enhanced in M2 macrophage and neutrophil co-cultures, indicating transcellular biosynthesis by a potential 15-LO and 5-LO mechanism
价 格:¥电议型 号:T38043产 地:中国大陆
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T375744-Nitrophenyl-N-acetyl-α-D-galactosaminide;4-Nitrophenyl-N-acetyl-α-D-galactosaminide4-Nitrophenyl-N
N-acetyl-D-galactosaminidase catalyzes the cleavage of N-acetylglucosamine (GlcNAc), the monomeric unit of the polymer chitin. 4-Nitrophenyl-N-acetyl-α-D-galactosaminide can be used as a chromogenic substrate for N-acetyl-D-galactosaminidase, generating a yellow solution upon cleavage.
价 格:¥电议型 号:T37574产 地:中国大陆
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T375734-Nitrophenyl β-D-Cellotetraoside;4-Nitrophenyl β-D-Cellotetraoside4-Nitrophenyl β-D-Cellotetraoside
4-Nitrophenyl β-D-Cellotetraoside can be used in related research in the field of life sciences. Its product number is T37573 and CAS number is 129411-62-7.
价 格:¥电议型 号:T37573产 地:中国大陆
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T375724-Nitrophenyl β-D-Cellotrioside;4-Nitrophenyl β-D-Cellotrioside4-Nitrophenyl β-D-Cellotrioside
4-Nitrophenyl β-D-cellotrioside is a chromogenic substrate for endoglucanases and cellobiohydrolases. Hydrolysis of this substrate by these enzymes liberates 4-nitrophenol, which generates a yellow color that is measured by monitoring absorbance at 405 nm.
价 格:¥电议型 号:T37572产 地:中国大陆
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T375694-Methylumbelliferyl-β-D-Galactoside;4-Methylumbelliferyl-β-D-Galactoside4-Methylumbelliferyl-β-D-Ga
4-Methylumbelliferyl-β-D-galactoside (MUG) is a fluorogenic substrate for β-galactosidase (β-gal).1Hydrolysis of MUG by β-gal releases the fluorescent moiety 4-MU, which displays a pH-dependent excitation maximum of 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively, and an emission maximum between 445-454 nm.2MUG has been used to detect β-gal activity in intact bacteria, yeast, and mammalian cells.1
价 格:¥电议型 号:T37569产 地:中国大陆
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T3749411-trans Leukotriene E4;11-trans Leukotriene E411-trans Leukotriene E4;11-trans Leukotriene E4
Slow isomerization of the C-11 double bond of LTE4 leads to the formation of 11-trans LTE4. 11-trans LTE4 is equipotent to LTE4 in contracting guinea pig ileum.
价 格:¥电议型 号:T37494产 地:中国大陆
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T373724,4-Diphenylbutylamine hydrochloride;4,4-Diphenylbutylamine hydrochloride4,4-Diphenylbutylamine hydr
4,4-Diphenylbutylamine shows affinity for the 5-HT2A and H1 receptors with Kis of 2589 and 1670 nM, respectively[1].
价 格:¥电议型 号:T37372产 地:中国大陆
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T3726214,15-Leukotriene E4;14,15-Leukotriene E414,15-Leukotriene E4;14,15-Leukotriene E4
Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. The majority of these metabolites are formed through the 5-lipoxygenase (5-LO) pathway. 14,15-LTE4 is a metabolite of 14,15-LTC4 and 14,15-LTD4, an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-LOs on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates. These metabolites are classified as eoxins because they are formed mostly by eosinophils
价 格:¥电议型 号:T37262产 地:中国大陆
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T36832PDE4B-IN-2;化合物PDE4B-IN-2A 33;A 33
PDE4B-IN-2 (A 33) is an orally active and selective PDE4B inhibitor with an IC50 of 15 nM. PDE4B-IN-2 inhibits PDE4D (IC50=1.7 ?M). PDE4B-IN-2 exhibits potent anti-inflammatory effects.
价 格:¥电议型 号:T36832产 地:中国大陆
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T36506Tempone;化合物Tempone4-Oxo-tempo;4-Oxo-tempo
Tempone is an aminooxyalkane that acts as a free radical scavenger and reacts with reactive oxygen species (ROS). Intravenous Tempone reduces mean arterial pressure in spontaneously hypertensive rats.
价 格:¥电议型 号:T36506产 地:中国大陆
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T361024-Chloro-6,7-bis(2-methoxyethoxy)quinazoline;4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline4-Chloro-6,
4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline is a building block and synthetic intermediate.1,2,3,4,5It has been used as a precursor in the synthesis of receptor tyrosine kinase (RTK) inhibitors, dual RTK and histone deacetylase (HDAC) inhibitors, and anticancer compounds.1,2,3It is also a synthetic intermediate in the synthesis of EGFR inhibitors, including erlotinib , with antiproliferative activity.4,5
价 格:¥电议型 号:T36102产 地:中国大陆
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T359704-hydroxy Nonenal Alkyne;4-hydroxy Nonenal Alkyne4-hydroxy Nonenal Alkyne
4-hydroxy Nonenal (4-HNE) is a major aldehyde produced during the lipid peroxidation of ω-6 polyunsaturated fatty acids, such as arachidonic acid and linoleic acid. It is considered a potential causal agent in numerous diseases, including chronic inflammation, neurodegenerative diseases, atherosclerosis, diabetes, and cancer, in part because it covalently modifies DNA and proteins resulting in genetic mutations and altered cell signaling, respectively. 4-HNE Alkyne is a form of 4-HNE with a term
价 格:¥电议型 号:T35970产 地:中国大陆
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T359494-Carboxypyrazole;4-Carboxypyrazole4-Carboxypyrazole
4-Carboxypyrazole is an endogenous metabolite.
价 格:¥电议型 号:T35949产 地:中国大陆
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T358404-Amino-6-chloro-1,3-benzenedisulfonamide;4-Amino-6-chloro-1,3-benzenedisulfonamide4-Amino-6-chloro-
4-Amino-6-chloro-1,3-benzenedisulfonamide is a carbonic anhydrase inhibitor.1 Formulations containing this compound are diuretics.2 4-Amino-6-chloro-1,3-benzenedisulfonamide is detected as a hydrolysis product of chlorothiazide in the urine.2 Diuretics, including chlorothiazide, have been abused as performance-enhancing drugs and masking agents in sports doping.3
价 格:¥电议型 号:T35840产 地:中国大陆
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T357264-hydroxy Xylazine;4-hydroxy Xylazine4-hydroxy Xylazine
4-hydroxy Xylazine is the hydroxylated xylazine metabolite.
价 格:¥电议型 号:T35726产 地:中国大陆
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T357214’-hydroxy Trazodone;4’-hydroxy Trazodone4’-hydroxy Trazodone
4’-hydroxy Trazodone is a metabolite of the antidepressant and sedative trazodone.1It is an inhibitor of organic anion transporter 3 (OAT3; Ki= 16.9 μM) and is selective for OAT3 over OAT1 (Ki= >200 μM).2
价 格:¥电议型 号:T35721产 地:中国大陆