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T9543Syk Inhibitor II hydrochlorideSyk Inhibitor II hydrochloride
The impact of spleen tyrosine kinase (Syk) signaling might be prominent in lupus because (i) Syk is a shared downstream signaling molecule among circulating immune complex, LPS, and (1→3)-β-D-glucan (BG), and (ii) all of these factors are detectable in the serum of Fc gamma receptor IIb-deficient (FcgRIIb-/-) mice with sepsis. Syk inhibition downregulated several inflammatory pathways in FcgRIIb-/- macrophages activated with BG + LPS suggesting the potential anti-inflammatory impact of Syk inhib
价 格:¥电议型 号:T9543产 地:中国大陆
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T7746Eltoprazine dihydrochlorideEltoprazine dihydrochloride
Eltoprazine dihydrochloride is a drug that had previously been developed for aggression, has recently been investigated for L-DOPA-induced dyskinesia in animal models of Parkinson′s disease (PD) and in dyskinetic PD patients.
价 格:¥电议型 号:T7746产 地:中国大陆
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T6426Buclizine dihydrochlorideteratogen,Inhibitor,MCF-7,anti-tumor activity,antiallergic,antihistamine,in
Buclizine HCl is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities. Buclizine binds to and blocks the histamine H1 receptor, thereby preventing the symptoms that are caused by histamine activity. Buclizine exerts its anti-emetic effect by binding to and blocking the muscarinic and histamine receptors in the vomiting center of the central nervous system (CNS). This may prevent activation of the chemorecepto
价 格:¥电议型 号:T6426产 地:中国大陆
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T10679Carcainium chloride
Carcainium chloride is a derivative of Lidocaine and possesses an antitussive effect.
价 格:¥电议型 号:T10679产 地:中国大陆
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T7488BD1063 dhydrochlorideSigma Receptor,Inhibitor,inhibit,BD1063 dhydrochloride,BD-1063 dhydrochloride
BD1063 is a potent and selective sigma 1(σ1) receptor antagonist(Ki = 9 nM).
价 格:¥电议型 号:T7488产 地:中国大陆
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T6441CGS 21680 HydrochlorideCGS-21680,Inhibitor,CGS 21680,inhibit,CGS21680,CGS 21680 Hydrochloride,Adenos
CGS 21680 HCl( IC50=22 nM), an adenosine receptor agonist, exhibits 140-fold potency in A2 receptor over A1 receptor.
价 格:¥电议型 号:T6441产 地:中国大陆
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T8543KN-92 hydrochlorideInhibitor,derivative,experimental,inactive,KN-92,KN92 hydrochloride,KN92,inhibit,
KN-92 hydrochloride is an inactive derivative of KN-93. KN-93 is a selective Ca2+/calmodulin-dependent kinase II (CaMKII) inhibitor, competitively blocking CaM binding to the kinase with Ki of 370 nM.
价 格:¥电议型 号:T8543产 地:中国大陆
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T7505Azimilide DihydrochlorideInhibitor,Azimilide,Azimilide Dihydrochloride,Potassium Channel,NE 10064,NE
Azimilide Dihydrochloride, a novel class III antiarrhythmic agent, blocks both the slowly activating (IKs) and rapidly activating (IKr) components of the delayed rectifier potassium current
价 格:¥电议型 号:T7505产 地:中国大陆
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T8004SNAP 94847 hydrochlorideAntidepressant,SNAP-94847,Melanin concentrating hormone receptor 1,anxiety,i
SNAP 94847 hydrochloride is a melanin-concentrating hormonereceptor1 (MCHR1) antagonist(Ki= 2.2 nM)
价 格:¥电议型 号:T8004产 地:中国大陆
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T10813Cilobradine hydrochloride
Cilobradine hydrochloride is an HCN Channel blocker and an open channel blocker of neuronal Ih and related cardiac If channels.
价 格:¥电议型 号:T10813产 地:中国大陆
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T7940Milnacipran ((1S-cis) hydrochloride)SERT,Milnacipran ((1S-cis) hydrochloride),F-2695,Milnacipran ((1
Milnacipran ((1S-cis) hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI), treatment of fibromyalgia.
价 格:¥电议型 号:T7940产 地:中国大陆
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T18640(S,R,S)-AHPC-C4-NH2 hydrochlorideinhibit,E3 Ligase Ligand-Linker Conjugates,(S,R,S)AHPCC4NH2 hydroch
(S,R,S)-AHPC-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker.
价 格:¥电议型 号:T18640产 地:中国大陆
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T21584CP 465022 hydrochlorideCP 465022 hydrochloride
CP 465022 hydrochloride is a potent, and selective noncompetitive antagonist of AMPA receptor with anticonvulsant activity. CP 465022 hydrochloride inhibits Kainate-induced response with an IC50 of 25 nM in rat cortical neurons.
价 格:¥电议型 号:T21584产 地:中国大陆
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T7508N-Acetylputrescine hydrochlorideinhibit,Inhibitor,N-Acetylputrescine,N Acetylputrescine hydrochlorid
N-Acetylputrescine is a polyamine commonly occurring excreted in normal human urine
价 格:¥电议型 号:T7508产 地:中国大陆
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T8840PF-543 hydrochlorideNrf-2,PF543 hydrochloride,anti-cancer,sphingosine-competitive,S1P,Sphingosine Ki
PF-543 inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.
价 格:¥电议型 号:T8840产 地:中国大陆
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T7143Alagebrium chlorideAlagebrium chloride,Endogenous Metabolite,ALT-711,Inhibitor,inhibit,Alagebrium,AL
Alagebrium Chloride is an advanced glycation end product (AGE) inhibitor, and has proven effective in reducing systolic blood pressure and providing therapeutic benefit for patients with diastolic
价 格:¥电议型 号:T7143产 地:中国大陆
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T10888CRT0066854 hydrochlorideCRT-0066854 hydrochloride,CRT0066854 hydrochloride
CRT0066854 hydrochloride is an effective selective atypical PKCs inhibitor. CRT0066854 is against full-length (FL) PKCι, PKCζ, and ROCK-II kinases with IC50 values of 132 nM, 639 nM, and 620 nM, respectively.
价 格:¥电议型 号:T10888产 地:中国大陆
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T8298Vasicine hydrochloridePeganine,Vasicine hydrochloride,Vasicine,inhibit,Inhibitor,Bacterial
Vasicine hydrochloride (peganine hydrochloride) is an alkaloid isolated from Justicia adhatoda. It possesses an anti-tuberculosis activity.
价 格:¥电议型 号:T8298产 地:中国大陆
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T63534PPTN hydrochloride
PPTN hydrochloride is a potent, high-affinity, competitive, highly selective P2Y14 receptor antagonist (KB: 434 pM), but no agonist or antagonist activity at P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12 or P2Y13 receptors, exhibiting anti-inflammatory and anti-immune effects.
价 格:¥电议型 号:T63534产 地:中国大陆
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T6464Detomidine hydrochlorideimidazole,Inhibitor,sedative,Detomidine hydrochloride,Beta Receptor,inhibit,
Detomidine HCl produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors.
价 格:¥电议型 号:T6464产 地:中国大陆