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T16842Saredutant；化合物 T16842SR 48968C|||SR 48968；SR 48968C|||SR 48968
Saredutant is an antagonist of selective NK2 receptors.
价 格：￥电议型 号：T16842产 地：中国大陆
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T16815RY796；化合物 T16815RY796
RY796 is an effective and selective inhibitor of voltage-gated potassium channel (IC50s: 0.25 μM and 0.09 μM for KV2.1 and KV2.2).
价 格：￥电议型 号：T16815产 地：中国大陆
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T16796RPR-260243；化合物 T16796RPR-260243
RPR-260243 is a novel activator of HERG and modifies HERG currents inhibited by dofetilide (IC50 = 58 nM).
价 格：￥电议型 号：T16796产 地：中国大陆
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T16771RO-5963；化合物RO-5963RO-5963
RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively).
价 格：￥电议型 号：T16771产 地：中国大陆
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T16748Ridinilazole；化合物RidinilazoleSMT19969；SMT19969
Ridinilazole (SMT19969) is a novel narrow-spectrum nonabsorbable antibiotic. Ridinilazole showed potent inhibition of C. difficile (MIC90=0.125 mg/L) and was markedly more active than either metronidazole (MIC90 = 8 mg/L) or vancomycin (MIC90 = 2 mg/L).
价 格：￥电议型 号：T16748产 地：中国大陆
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T16696Pyriproxyfen；吡丙醚S-31183；S-31183|||吡丙醚
Pyriproxyfen (S-31183) is an insecticide that acts as a biomimetic of juvenile hormone.
价 格：￥电议型 号：T16696产 地：中国大陆
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T16596Propargyl-PEG12-OH；化合物 T16596Propargyl-PEG12-OH
Propargyl-PEG12-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T16596产 地：中国大陆
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T16557PNU-159682；化合物PNU-159682PNU-159682
PNU-159682 is a highly effective metabolite of the anthracycline nemorubicin. PNU-159682 has outstanding cytotoxicity. PNU-159682 is an effective ADCs cytotoxin.
价 格：￥电议型 号：T16557产 地：中国大陆
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T16496PF-06795071；化合物 T16496PF-06795071
PF-06795071 is an effective and selective covalent inhibitor of MAGL (IC50: 3 nM).
价 格：￥电议型 号：T16496产 地：中国大陆
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T16406Orvepitant maleate；化合物 T16406GW823296 maleate；GW823296 maleate
Orvepitant maleate is an effective, selective, and well-tolerated neurokinin-1 receptor (NK-1) antagonist (pKi: 10.2 for human neurokinin-1 receptor). Orvepitant maleate has the potential for depressive disorder and chronic refractory cough (CRC) treatment. Orvepitant maleate can across the blood-brain barrier.
价 格：￥电议型 号：T16406产 地：中国大陆
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T16401Org-12962；化合物Org-12962Org-12962
Org-12962 is an effective and selective 5-HT2C?receptor agonist pEC50: 7.01). Org-12962 shows antiaversive effects in a rat model of panic-like anxiety. Org-12962 also shows high effacy for the 5-HT2A?and 5-HT2B receptors (pEC50s: 6.38 and 6.28, respectively).
价 格：￥电议型 号：T16401产 地：中国大陆
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T16396OP-3633；化合物 T16396OP-3633
OP-3633 is an effective and selective steroidal glucocorticoid receptor (GR) antagonist (IC50: 29 nM). OP-3633 shows low progesterone receptor (PR) agonism and androgen receptor (AR) antagonism. It also has an inhibition of GR transcriptional activity.
价 格：￥电议型 号：T16396产 地：中国大陆
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T16340Nosiheptide那西肽RP 9671|||Multhiomycin|||那西肽
Nosiheptide (Multhiomycin), a thiopeptide antibiotic synthesized by Streptomyces actuosus, serves as a potent feed additive to promote animal growth. It functions by hindering bacterial protein synthesis and is distinguished by an indole side ring system and regiospecific hydroxyl groups on its macrocyclic core.
价 格：￥电议型 号：T16340产 地：中国大陆
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T16296NH-bis(C2-PEG2-NH-Boc)；化合物 T16296NH-bis(C2-PEG2-NH-Boc)
NH-bis(C2-PEG2-NH-Boc) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T16296产 地：中国大陆
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T16270Nanatinostat；化合物 T16270CHR-3996；CHR-3996
Nanatinostat is an effective and class I selective inhibitor of histone deacetylase (IC50: 8 nM).
价 格：￥电议型 号：T16270产 地：中国大陆
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T16268Namitecan；化合物 T16268ST-1968；ST-1968
Namitecan is an effective inhibitor of topoisomerase I. It has antitumor property.
价 格：￥电议型 号：T16268产 地：中国大陆
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T1622Rosiglitazone maleate；马来酸罗格列酮BRL 49653C|||BRL 49653；BRL 49653C|||BRL 49653|||马来酸罗格列酮
Rosiglitazone maleate (BRL 49653) is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity.
价 格：￥电议型 号：T1622产 地：中国大陆
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T16196N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester)；化合物 T16196N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester)
N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a polyethylene glycol (PEG)-based linker employed in the synthesis of proteolysis-targeting chimeras (PROTACs).
价 格：￥电议型 号：T16196产 地：中国大陆
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T1616Cefotiam hydrochloride；盐酸头孢替安Pansporin|||SCE-963 hydrochloride|||Pansporine|||Cefotiam dihydrochlori
Cefotiam hydrochloride (SCE-963 hydrochloride) is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.
价 格：￥电议型 号：T1616产 地：中国大陆
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T16142MRT199665；化合物 T16142MRT199665
MRT199665 is an effective and ATP-competitive, selective MARK/SIK/AMPK inhibitor (IC50s of 2/2/3/2 nM, 10/10 nM, and 110/12/43 nM for MARK1/MARK2/MARK3/MARK14, AMPKα1/AMPKα2, and SIK1/SIK2/SIK3, respectively). MRT199665 suppresses the phosphorylation of SIK substrate CRTC3 at S370. MRT199665 induces apoptosis in MEF2C-activated human acute myeloid leukemia (AML) cells.
价 格：￥电议型 号：T16142产 地：中国大陆
