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T37313ITH15004；ITH15004ITH15004
ITH15004 is a non-nucleotide antagonist of the purinergic P2X7receptor (IC50= 9 μM in HEK293 cells expressing the human receptor).1It inhibits ATP-induced currents inX. laevisoocytes expressing the human P2X7receptor when used at a concentration of 100 μM. ITH15004 (1 μM) decreases IL-1β release from LPS-primed, ATP-stimulated isolated mouse peritoneal macrophages. It has high permeability in a parallel artificial membrane permeability assay (PAMPA).
价 格：￥电议型 号：T37313产 地：中国大陆
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T37312Isotachysterol 3；异速甾醇3Isotachysterol 3
Isotachysterol 3, an analog of 1,25-dihydroxy Vitamin D3, was found to enhance intestinal calcium transport and stimulate bone calcium mobilization in anephric rats[1].
价 格：￥电议型 号：T37312产 地：中国大陆
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T37311Dichloroiodomethane；DichloroiodomethaneDichloroiodomethane
Dichloroiodomethane is a natural compound in human beings[1].
价 格：￥电议型 号：T37311产 地：中国大陆
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T37310Diadenosine pentaphosphate pentasodium；Diadenosine pentaphosphate pentasodiumDiadenosine pentaphosph
Diadenosine pentaphosphate pentasodium, an endogenous vasoactive purine dinucleotide isolated from thrombocytes, serves as a key component of secretory vesicles in platelets, chromaffin cells, Torpedo synaptic terminals, and brain synaptosomes. This compound, along with other diadenosine polyphosphates (ApnA, n=2-7), plays a crucial role in physiological processes[1][2].
价 格：￥电议型 号：T37310产 地：中国大陆
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T3731Hydrocinnamic acid；氢化肉桂酸3-Phenylpropanoic acid|||3-Phenylpropionic acid|||3-Phenyl-n-propionic acid；
Hydrocinnamic acid (3-Phenylpropanoic acid) is a carboxylic acid belonging to the class of phenylpropanoids. It is a white, crystalline solid with a sweet, floral scent at room temperature. Hydrocinnamic acid has a wide variety of uses including cosmetics, food additives, and pharmaceuticals.
价 格：￥电议型 号：T3731产 地：中国大陆
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T37309Diadenosine pentaphosphate pentaammonium；Diadenosine pentaphosphate pentaammoniumDiadenosine pentaph
Diadenosine pentaphosphate pentaammonium, an endogenous vasoactive purine dinucleotide isolated from thrombocytes, is one component of the diadenosine polyphosphates (ApnA, n=2-7) family. These compounds are found in secretory vesicles, including those in platelets, chromaffin cells, Torpedo synaptic terminals, and brain synaptosomes[1][2].
价 格：￥电议型 号：T37309产 地：中国大陆
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T37308Desmethylene Paroxetine hydrochloride；Desmethylene Paroxetine 盐酸盐Desmethylene Paroxetine hydrochlori
Desmethylene Paroxetine hydrochloride is a non-conjugated metabolite of Paroxetine, a catechol intermediate.
价 格：￥电议型 号：T37308产 地：中国大陆
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T37307Nordoxepin hydrochloride；Desmethyldoxepin (hydrochloride)Nordoxepin hydrochloride
Doxepin is a tricyclic antidepressant. Desmethyldoxepin is the primary metabolite of doxepin, produced by metabolism at the liver. The metabolism of tricyclic antidepressants, including doxepin, is affected by a variety of factors, including age, genetics, and drug-drug interactions.
价 格：￥电议型 号：T37307产 地：中国大陆
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T373066-hydroxy Chlorzoxazone；6-hydroxy Chlorzoxazone6-hydroxy Chlorzoxazone|||NSC 24955；6-hydroxy Chlorzo
6-hydroxy Chlorzoxazone is a metabolite of chlorzoxazone. [1] It is formed by metabolism of chlorzoxazone by the cytochrome P450 (CYP) isoform CYP2E1 in human hepatic microsomes.
价 格：￥电议型 号：T37306产 地：中国大陆
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T373056(S)-Lipoxin A4；6(S)-Lipoxin A46Lipoxin A4|||6(S)-Lipoxin A4|||6(S)-Lipoxin A4|||6(S) Lipoxin A4|||6
The lipoxins are trihydroxy fatty acids containing a 7,9,11,13-conjugated tetraene. Lipoxin A4 (LXA4) was first described as a metabolite of 15-HpETE and/or 15-HETE when added in vitro to isolated human leukocytes. The material obtained in this manner consists of at least four distinct isomers: 5(S), 6(S); 5(S), 6(R); and the 11-trans and 11-cis isomers of each of these. 6(S)-LXA4 is one of the original four metabolites first identified by Serhan, Nicolaou, and Samuelsson. It was considered to b
价 格：￥电议型 号：T37305产 地：中国大陆
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T373045-OxoETE methyl ester；5-OxoETE methyl ester5-OxoETE methyl ester
5-OxoETE methyl ester is an esterified form of the polyunsaturated keto acid 5-oxoETE . 5-OxoETE methyl ester is an agonist of oxoeicosanoid receptor 1 (OXER1; EC50 = 1.54 μM for β-arrestin recruitment) that has a higher maximal response than 5-oxoETE in a β-arrestin assay.
价 格：￥电议型 号：T37304产 地：中国大陆
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T373035-OxoETE；5-OxoETE5-KETE|||5-OxoETE；5-KETE|||5-OxoETE
5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils by a specific dehydrogenase.[1] It stimulates cytosolic calcium levels in neutrophils with an EC50 value of 2 nM.[2] 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the MAPK pathway in stimulated neutrophils via a specific G protein-coupled receptor.[3],[4],[5],[6]
价 格：￥电议型 号：T37303产 地：中国大陆
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T37302PCTR3；PCTR3PCTR3
Protein conjugates in tissue regeneration 3 (PCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to PCTR1 by glutathione S-transferase and to PCTR2 and PCTR3 via peptidases. PCTR3 is found in infected mouse spleens and resolving exudate as well as isolated human spleen and septic plasma. It is also found in both M1 and M2 macrophages differentiated from isolated human monocytes.
价 格：￥电议型 号：T37302产 地：中国大陆
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T37301PCTR2；PCTR2PCTR2
Protein conjugates in tissue regeneration 2 (PCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to PCTR1 by glutathione S-transferase and to PCTR2 via γ-glutamyl transpeptidase. PCTR2 is found in resolving mouse exudate and in both M1 and M2 macrophages differentiated from isolated human monocytes.
价 格：￥电议型 号：T37301产 地：中国大陆
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T37300PCTR1；PCTR1PCTR1；PCTR1
Protectin conjugates in tissue regeneration 1 (PCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is then converted to PCTR1 by glutathione S-transferase. PCTR1 levels increase during resolution of acute microbial-induced peritonitis in mice. PCTR1 (30 ng, i.p.) administration 12 hours post-infection increases macrophage numbers and activity and shortens the resolution phase of inflammation by 57%. It als
价 格：￥电议型 号：T37300产 地：中国大陆
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T3730Methyl gallate；没食子酸甲酯NSC 363001|||Gallicin|||Gallic acid methyl ester|||Gallincin；NSC 363001|||Galli
Methyl gallate (Gallincin) is a reverse transcriptase inhibitor with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibition activities.
价 格：￥电议型 号：T3730产 地：中国大陆
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T37273BLX3887；BLX3887BLX3887
BLX3887 is an inhibitor of 15-lipoxygenase type 1 (15-LO-1; IC50 = 32 nM in a cell-free enzyme assay).1 It is selective for 15-LO-1 over 15-LO-2, which it does not inhibit, 5-LO (IC50 = 472 nM), and 12-LO (IC50 = 3,310 nM). BLX3887 inhibits the production of 15-LO metabolites selectively in eosinophils over neutrophils when used at a concentration of 10 μM. It also inhibits endocytosis in, and the migration of, isolated human peripheral blood mononuclear cell-derived dendritic cells in vitro.
价 格：￥电议型 号：T37273产 地：中国大陆
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T37173Bofutrelvir；福布特韦DC-402234|||MPro Inhibitor 11a|||FB2001；DC-402234|||MPro Inhibitor 11a|||FB2001
Bofutrelvir (FB2001) is a SARS-CoV-2 3CL protease inhibitor with antiviral activity for the study of novel coronavirus pneumonia (COVID-19) infections.
价 格：￥电议型 号：T37173产 地：中国大陆
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T3716Rolapitant；罗拉匹坦SCH619734；罗拉吡坦|||SCH619734|||罗拉匹坦
Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant competitively binds to and blocks the activity of the NK1-receptor in the central nervous system, thereby inhibiting the binding of the endogenous ligand, substance P (SP). This may prevent both SP-induced emesis and chemotherapy-induced nause
价 格：￥电议型 号：T3716产 地：中国大陆
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T37073LP 12 hydrochloride；LP 12 hydrochlorideLP 12 hydrochloride
LP 12 hydrochloride is a selective 5-HT7 receptor agonist (Ki=0.13 nM). LP 12 hydrochloride is selective for 5-HT7 over D2, 5-HT1A, and 5-HT2A receptors (Ki values of 224 nM, 60.9 nM, and >1000 nM, respectively).
价 格：￥电议型 号：T37073产 地：中国大陆
