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  • T14544Benzyloxy carbonyl-PEG3-NHS ester；化合物 T14544Benzyloxy carbonyl-PEG3-NHS ester

    Benzyloxy carbonyl-PEG3-NHS ester is a polyethylene glycol (PEG) derivative compound used as a PROTAC linker in the synthesis of PROTACs[1].

    价 格：￥电议型 号：T14544产 地：中国大陆

  • T14499Bax activator-1；化合物 T14499Bax activator-1

    Bax activator-1 (compound 106) is a Bax activator. It induces Bax-dependent tumor cell apoptosis[1].

    价 格：￥电议型 号：T14499产 地：中国大陆

  • T14498Barbadin；化合物 BarbadinBarbadin

    Barbadin is a novel and specific inhibitor of β-arrestin/β2-adaptin interaction with an IC50 value of 19.1 μM for β-arestin1 and 15.6 μM for β-arestin2. Barbadin potentiates the long term effects of lorcaserin on POMC neurons and weight loss. Barbadin potentiates the long-term effects of lorcaserin on POMC neurons and weight loss, blocks agonist-promoted endocytosis of prototypic β2-adrenergic, V2-vasopressin, and angiotensin-II-1 receptors, and may be useful in the study of obesity.

    价 格：￥电议型 号：T14498产 地：中国大陆

  • T14497BAM 15；化合物BAM 15BAM 15

    BAM 15 is an uncoupler of mitochondrial protonophore.

    价 格：￥电议型 号：T14497产 地：中国大陆

  • T14496BAMB-4；化合物BAMB-4ITPKA-IN-C14；ITPKA-IN-C14

    BAMB-4 (ITPKA-IN-C14) is a highly membrane-permeable inhibitor of inositol-1,4,5-trisphosphate-3-kinase A (ITPKA). It acts by suppressing the metastasis-promoting effect of ITPKA in lung tumor cells(with IC50 of 37 μM in ADP-Glo Assay).

    价 格：￥电议型 号：T14496产 地：中国大陆

  • T14495Baloxavir巴洛沙韦Baloxavir acid|||S-033447

    Baloxavir (S-033447) is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit.

    价 格：￥电议型 号：T14495产 地：中国大陆

  • T14494Balovaptan；化合物BalovaptanRG7314；RG7314

    Balovaptan (RG7314) is a highly potent and selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors. It is used for the research of autism.

    价 格：￥电议型 号：T14494产 地：中国大陆

  • T14493Balapiravir化合物 T14493R1626|||Ro 4588161

    Balapiravir (R1626, Ro 4588161) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479). IC50 Value: Target: HCV Balapiravir was discontinued for safety reasons in 28-36% of patients (most often for lymphopenia) and the percentage of patients with serious adverse events (especially hematological, infection, ocular events) was dose related. Balapiravir (R1626) is the tri-isobutyrate ester prodrug of R1479 under clinical develop

    价 格：￥电议型 号：T14493产 地：中国大陆

  • T14492BAL-30072；化合物 T14492BAL-30072

    BAL30072 shows MIC90 values of 4 μg/mL for MDR Acinetobacter spp. and 8 μg/mL for MDR P. aeruginosa, respectively[1][2]. BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against multiresistant gram-negative bacilli.

    价 格：￥电议型 号：T14492产 地：中国大陆

  • T14491B022化合物 B022B022|||B-022

    B022 is a selective and potent NF-κB-induced kinase (NIK) inhibitor (Ki: 4.2 nM), a chemical probe for the treatment of liver inflammation and injury.B022 protects the liver from inflammation and injury caused by oxidative stress and toxins.

    价 格：￥电议型 号：T14491产 地：中国大陆

  • T14490Talipexole dihydrochloride；盐酸他利克索Domnin|||B-HT 920 dihydrochloride；Domnin|||盐酸他利克索|||B-HT 920 dihydr

    Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and intestinal membrane fractions with Ki values of 0.35 μM and 0.22 μM, respectively. It displays antiParkinsonian activity.

    价 格：￥电议型 号：T14490产 地：中国大陆

  • T1448LDasatinib monohydrate；达沙替尼BMS-354825 Monohydrate；达沙替尼|||BMS-354825 Monohydrate

    Dasatinib monohydrate (BMS-354825 Monohydrate) is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib monohydrate binds to and inhibits the growth-promoting activities of these kinases. Apparently, because of its less stringent binding affinity for the BCR-ABL kinase, Dasatinib monohydrate has been shown to overcome the resistance to imatinib of chronic myeloid leukemia (CML) cells harboring BCR-ABL kinase domain point mutations.

    价 格：￥电议型 号：T1448L产 地：中国大陆

  • T14489Azvudine；化合物AzvudineFNC|||RO-0622；4-氨基-1-(4-C-叠氮基-2-脱氧-2-氟-BETA-D-呋喃阿拉伯糖基)-2(1H)-嘧啶酮|||FNC|||RO-0622

    Azvudine (FNC) is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine inhibits NRTI-resistant viral strains. Azvudine exerts highly potent inhibition on HIV-1 (EC50s ranging from 0.03 to 6.92 nM) and HIV-2 (EC50s ranging from 0.018 to 0.025 nM).

    价 格：￥电议型 号：T14489产 地：中国大陆

  • T14488Azt-pmap；化合物 T14488Azt-pmap

    AZT-PMPA, an aryl phosphate derivative of AZT and a nucleoside analogue, demonstrates anti-HIV activity[1]. As a nucleoside reverse transcriptase inhibitor (NRTI), AZT-PMPA targets HIV infection effectively[2].

    价 格：￥电议型 号：T14488产 地：中国大陆

  • T14487AZM475271；化合物 T14487M475271；M475271

    AZM475271 is a potent and selective inhibitor of Src kinase(IC50 : 5 nM)

    价 格：￥电议型 号：T14487产 地：中国大陆

  • T14486Azidoethyl-SS-PEG2-Boc；化合物 T14486Azidoethyl-SS-PEG2-Boc

    Azidoethyl-SS-PEG2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T14486产 地：中国大陆

  • T14485Azidoethyl-SS-ethylazide；化合物 T14485Azidoethyl-SS-ethylazide

    Azidoethyl-SS-ethylazide is a cleavable linker employed for the synthesis of antibody-drug conjugates (ADCs)[1].

    价 格：￥电议型 号：T14485产 地：中国大陆

  • T14484Azidoethyl-SS-ethylamine；化合物 T14484Azidoethyl-SS-ethylamine

    Azidoethyl-SS-ethylamine is a cleavable linker compound employed for the synthesis of antibody-drug conjugates (ADCs)[1].

    价 格：￥电议型 号：T14484产 地：中国大陆

  • T14483Azido-PEG9-Boc；化合物 T14483Azido-PEG9-Boc

    Azido-PEG9-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T14483产 地：中国大陆

  • T14482Azido-PEG9-amine；化合物 T14482Azido-PEG9-amine

    Azido-PEG9-amine is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

    价 格：￥电议型 号：T14482产 地：中国大陆

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