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T19159Mal-β-CD化合物 Mal-β-CD6-O-alpha-D-Maltosyl-beta-cyclodextrin
Mal-β-CD is a cellular cholesterol modifier. It can form a soluble inclusion complex with cholesterol.
价 格：￥电议型 号：T19159产 地：中国大陆
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T19059Solvent Yellow 93；溶剂黄93Solvent Yellow 93
Solvent Yellow 93, an azomethine dye, is used as a colorant of toner.
价 格：￥电议型 号：T19059产 地：中国大陆
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T18959D-Ala-Lys-AMCA；化合物 T18959D-Ala-Lys-AMCA
D-Ala-Lys-AMCA is a known substrate of proton-coupled oligopeptide transporter 1 (PEPT1) that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into Caco-2 cells and liver cancer cells.
价 格：￥电议型 号：T18959产 地：中国大陆
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T18859Tri(Mal-PEG2-amide)-amine；化合物 T18859Tri(Mal-PEG2-amide)-amine
Tri(Mal-PEG2-amide)-amine is a polyethylene glycol (PEG)-derived linker commonly employed for synthesizing proteolysis-targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T18859产 地：中国大陆
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T18759TCO-PEG2-Sulfo-NHS ester；化合物 T18759TCO-PEG2-Sulfo-NHS ester
TCO-PEG2-Sulfo-NHS ester is a Polyethylene glycol (PEG)-based linker for PROTAC synthesis[1].
价 格：￥电议型 号：T18759产 地：中国大陆
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T18659S-Bis-(PEG4-Boc)；化合物 T18659S-Bis-(PEG4-Boc)
S-Bis-(PEG4-Boc) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T18659产 地：中国大陆
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T18599PROTAC BRD4-binding moiety 1；化合物 T18599PROTAC BRD4-binding moiety 1
PROTAC BRD4-binding moiety 1 is a BRD4 ligand that binds to the cereblon ligand through a linker, enabling the formation of a PROTAC complex. This complex efficiently degrades BRD4[1].
价 格：￥电议型 号：T18599产 地：中国大陆
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T18598PROTAC BRD2/BRD4 degrader-1；化合物 T18598PROTAC BRD2/BRD4 degrader-1
PROTAC BRD2/BRD4 degrader-1 (compound 15) serves as a potent, selective degrader of BET proteins BRD4 and BRD2, achieving rapid, reversible, and unexpectedly selective elimination of BRD4 and BRD2 compared to BRD3. Its efficacy in suppressing solid tumors manifest with minimal cytotoxic effects. This compound comprises a BET inhibitor, a connecting linker, and thalidomide as the ligand for cereblon (CRBN)/cullin 4A[1].
价 格：￥电议型 号：T18598产 地：中国大陆
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T18597dFKBP-1；化合物 T18597dFKBP-1
dFKBP-1 is a potent and PROTAC-based FKBP12 degrader. dFKBP-1 incorporates the ligand SLF of FKBP12, the Thalidomide based cereblon ligand and a linker[1].
价 格：￥电议型 号：T18597产 地：中国大陆
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T18595Dasatinib carbaldehyde；化合物Dasatinib carbaldehydePROTAC ABL binding moiety 4|||BMS-354825 carbaldehyd
Dasatinib carbaldehyde (PROTAC ABL binding moiety 4) is based on Dasatinib which is an ABL inhibitor, binds to the IAP ligand via a linker, and forms SNIPER [1].
价 格：￥电议型 号：T18595产 地：中国大陆
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T18594HG-7-85-01-Decyclopropane；化合物 T18594PROTAC ABL binding moiety 3；PROTAC ABL binding moiety 3
Decyclopropane, also known as HG-7-85-01, is a chemical compound with ABL inhibitor properties. It binds to the IAP ligand through a linker, resulting in the formation of SNIPER [1].
价 格：￥电议型 号：T18594产 地：中国大陆
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T18593GNF5-amido-Me；化合物 T18593PROTAC ABL binding moiety 2；PROTAC ABL binding moiety 2
GNF5-amido-Me, the moiety based on GNF5 (ABL inhibitor),binds through a linker to the IAP ligand forming SNIPER[1].
价 格：￥电议型 号：T18593产 地：中国大陆
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T18592Imatinib carbaldehyde；化合物 T18592CGP-57148B carbaldehyde|||STI571 carbaldehyde|||PROTAC ABL binding m
Imatinib carbaldehyde (also known as CGP-57148B carbaldehyde) is a compound derived from Imatinib, an inhibitor of the ABL protein. Imatinib carbaldehyde binds to the IAP ligand with the assistance of a linker, resulting in the formation of SNIPER[1].
价 格：￥电议型 号：T18592产 地：中国大陆
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T18591Propargyl-PEG8-SH；化合物 T18591Propargyl-PEG8-SH
Propargyl-PEG8-SH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T18591产 地：中国大陆
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T18590Propargyl-PEG7-methane；化合物 T18590Propargyl-PEG7-methane
Propargyl-PEG7-methane is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T18590产 地：中国大陆
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T1859AZD-8055；化合物AZD8055AZD-8055
AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.
价 格：￥电议型 号：T1859产 地：中国大陆
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T18559PPC-NHS ester；化合物 T185592,5-Dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate；2,5-Dioxopyrrol
PPC-NHS ester is a cleavable linker vital in ADC synthesis. PPC-NHS ester joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
价 格：￥电议型 号：T18559产 地：中国大陆
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T18359Methyltetrazine-SS-PEG4-Biotin；化合物 T18359Methyltetrazine-SS-PEG4-Biotin
Methyltetrazine-SS-PEG4-Biotin is a cleavable four-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T18359产 地：中国大陆
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T18302Mal-Phe-C4-VC-PAB-DMEA-PNU-159682；化合物 T18302Mal Phe C4 VC PAB DMEA PNU 159682|||Mal-Phe-C4-VC-PAB-DM
Mal-Phe-C4-VC-PAB-DMEA-PNU-159682 is a drug-linker conjugate utilized in antibody-drug conjugate (ADC) therapy. It comprises the ADC linker Mal-Phe-C4-VC-PAB and the potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 encompasses metabolites of nemorubicin (MMDX) derived from liver microsomes, as well as the ADC cytotoxin PNU-159682[1].
价 格：￥电议型 号：T18302产 地：中国大陆
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T18292Mal-PEG4-VC-PAB-DMEA-PNU-159682；化合物 T18292Mal-PEG4-VC-PAB-DMEA-PNU159682|||MalPEG4VCPABDMEAPNU159682
Mal-PEG4-VC-PAB-DMEA-PNU-159682 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) therapy. It combines the ADC linker, Mal-PEG4-VC-PAB, with the potent ADC cytotoxin, DMEA-PNU-159682. The cytotoxin, DMEA-PNU-159682, is derived from metabolites of nemorubicin (MMDX) found in liver microsomes, as well as the ADC cytotoxin PNU-159682[1].
价 格：￥电议型 号：T18292产 地：中国大陆
