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T14991CMS-121;化合物CMS-121CMS121;CMS121
CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage (EC50: 7 nM and 200 nM). CMS-121 shows strong neuroprotective, antioxidative, anti-inflammatory, and renoprotective activities.
价 格:¥电议型 号:T14991产 地:中国大陆
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T14919CDKI-73;化合物CDKI-73CDKI-73
CDKI-73 is a potent CDK9 inhibitor (Ki: 4 nM). It shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM).The inhibition of CDK9 induces apoptosis and potentiates the effect of cisplatin.
价 格:¥电议型 号:T14919产 地:中国大陆
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T14916CDK2-IN-4;化合物CDK2-IN-4CDK2-IN-4
CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A. It shows 2,000-fold selectivity over CDK1/cyclin B with IC50 of 86 uM.
价 格:¥电议型 号:T14916产 地:中国大陆
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T14915CDK12-IN-E9;化合物 T14915CDK12-IN-E9
CDK12-IN-E9 is a potent and selective covalent CDK12 inhibitor and non-covalent CDK9 inhibitor while avoiding ABC transporter-mediated efflux. It has a weak binding ability to CDK7/CyclinH complex (IC50> 1 μM).
价 格:¥电议型 号:T14915产 地:中国大陆
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T14914Cdk1/2 Inhibitor III;Cdk1/2 抑制剂IIICdk1/2 Inhibitor III
Cdk1/2 Inhibitor III is a selective Cdk1/2 inhibitor with an IC50 value of 2.1 μM against CDK1/cyclin B.
价 格:¥电议型 号:T14914产 地:中国大陆
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T14913CD38 inhibitor 1;化合物CD38 inhibitor 1CD38 inhibitor 1
CD38 inhibitor 1 is an inhibitor of CD38. For hCD38 and mouse CD38, the IC50s are 7.3 nM and 1.9 nM.
价 格:¥电议型 号:T14913产 地:中国大陆
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T14912CD3254;化合物CD3254CD3254
CD3254 is a selective and potent retinoid X receptor-like (RXR) agonist that inhibits neuronal cell death with OGD/reoxygenation.
价 格:¥电议型 号:T14912产 地:中国大陆
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T14911CD2665;化合物CD2665CD2665
CD2665 is an orally active antagonist of retinoic acid receptor (RAR). For RARγ and RARβ, the Kis are 110 nM and 306 nM.
价 格:¥电议型 号:T14911产 地:中国大陆
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T14910CD161;化合物 T14910NKR-P1A;NKR-P1A
CD161 is a potent, selective, and orally bioavailable BET bromodomain inhibitor (IC50s: 28.2 nM and 7.2 nM for BRD4 BD1 and BRD4 BD2) with good anticancer activity.
价 格:¥电议型 号:T14910产 地:中国大陆
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T1491Atovaquone;阿托伐醌Atavaquone;Atavaquone|||阿托伐醌
Atovaquone (Atavaquone) is a hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols.
价 格:¥电议型 号:T1491产 地:中国大陆
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T14891Cbz-NH-PEG6-C2-acid;化合物 T14891Cbz-NH-PEG6-C2-acid
Cbz-NH-PEG6-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14891产 地:中国大陆
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T14885CBS9106;化合物 CBS9106Felezonexor|||SL-801;Felezonexor|||SL-801
CBS9106 (SL-801) is a reversible oral CRM1 inhibitor with CRM1 degrading and antitumor activity.CBS9106 inhibits CRM1-dependent nuclear export and reduces CRM1 protein levels.CBS9106 inhibits tumor growth and prolongs the survival of mice bearing tumor xenografts.CBS9106 is an inhibitor of CRM1-dependent nuclear export and reduces CRM1 protein levels.
价 格:¥电议型 号:T14885产 地:中国大陆
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T14879CB 300919;化合物 T14879CB 300919
CB 300919 is a quinazoline-based antitumor agent with high activity in the CH1 human ovarian tumor xenograft and has continuous exposure (96 h) growth inhibition (IC50: 2 nM).
价 格:¥电议型 号:T14879产 地:中国大陆
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T14791Bromo-PEG2-C2-Boc;化合物 T14791Bromo-PEG2-C2-Boc
Bromo-PEG2-C2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14791产 地:中国大陆
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T14780BRD9185;化合物 T14780BRD9185
BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.
价 格:¥电议型 号:T14780产 地:中国大陆
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T1476Pramipexole;普拉克索SND 919;SND 919|||普拉克索
Pramipexole (SND 919) is a selective dopamine receptor agonist used in the therapy of Parkinson disease. Pramipexole therapy is associated with a low rate of transient serum enzyme elevations during treatment but has not been implicated in cases of clinically apparent acute liver injury.
价 格:¥电议型 号:T1476产 地:中国大陆
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T14691BMT-090605;化合物 T14691BMT-090605
BMT-090605 is a potent, selective AAK1 inhibitor, with an IC50 of 0.6 nM. BMT-090605 inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK) with IC50s of 45 and 60 nM, respectively[1]. BMT-090605 shows antinociceptive activity.
价 格:¥电议型 号:T14691产 地:中国大陆
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T1465Mupirocin;莫匹罗星Pseudomonic acid|||BRL-4910A;Pseudomonic acid|||莫匹罗星|||BRL-4910A
Mupirocin (BRL-4910A) is a RNA synthetase inhibitor antibacterial. It has shown excellent activity against gram-positive staphylococci and streptococci.
价 格:¥电议型 号:T1465产 地:中国大陆
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T14591Biotin-PEG3-azideN-[2-[2-[2-(2-叠氮乙氧基)乙氧基]乙氧基]乙基]生物素胺N-[2-[2-[2-(2-叠氮乙氧基)乙氧基]乙氧基]乙基]生物素胺
Biotin-PEG3-azide is a PEG-based PROTAC linker can be used in PROTAC synthesis.
价 格:¥电议型 号:T14591产 地:中国大陆