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T16803RS 8359;化合物RS 8359RS 8359
RS 8359 is a reversible inhibitor of monoamine oxidase A (MAO-A) with a selectivity ratio of about 2200 for the A:B enzyme types. RS 8359 has antidepressant activity.
价 格:¥电议型 号:T16803产 地:中国大陆
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T16771RO-5963;化合物RO-5963RO-5963
RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively).
价 格:¥电议型 号:T16771产 地:中国大陆
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T16759Ritanserin;利坦丝林R 55667;利坦丝林|||R 55667
Ritanserin (R 55667) is a highly effective, relatively selective, long-acting antagonist of 5-HT2 receptor (IC50: 0.9 nM), less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors.
价 格:¥电议型 号:T16759产 地:中国大陆
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T16751Rilapladib;瑞拉帕地SB 659032;SB 659032
Rilapladib (SB 659032) is a selective inhibitor of Lipoprotein-Associated Phospholipase A2(Lp-PLA2, IC50 = 230 pM) and an antagonist of the platelet activating factor receptor.
价 格:¥电议型 号:T16751产 地:中国大陆
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T16709R 59-022;化合物 T16709Diacylglycerol kinase inhibitor I|||DKGI-I;Diacylglycerol kinase inhibitor I|||DK
R 59-022 is a 5-HTR antagonist and activates protein kinase C (PKC). R 59-022 is a diacylglycerol kinase inhibitor (IC50=2.8 μM). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils.
价 格:¥电议型 号:T16709产 地:中国大陆
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T16704LQuilseconazole Formic acid(1340593-70-5 Free base);化合物 Quilseconazole Formic acid(1340593-70-5 Free
Quilseconazole Formic acid is a selective inhibitor of fungal Cyp51 with potent activities against Cryptococcus neoformans and Cryptococcus gattii.
价 格:¥电议型 号:T16704L产 地:中国大陆
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T16659Boc-NH-PEG2-C2-NH2;化合物 T16659PROTAC Linker 13;PROTAC Linker 13
Boc-NH-PEG2-C2-NH2 (PROTAC Linker 13) is a PEG-based linker utilized for the synthesis of PROTACs. This chemical compound plays a crucial role in connecting the targeted protein and the E3 ubiquitin ligase for selective protein degradation[1].
价 格:¥电议型 号:T16659产 地:中国大陆
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T16599Propargyl-PEG3-NHS ester;化合物 T16599Propargyl-PEG3-NHS ester
Propargyl-PEG3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T16599产 地:中国大陆
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T16598Propargyl-PEG2-amine2-(2-(丙-2-炔-1-基氧基)乙氧基)乙胺2-(2-(丙-2-炔-1-基氧基)乙氧基)乙胺
Propargyl-PEG2-amine is a non-cleavable ADC linker employed for synthesizing antibody-drug conjugates (ADCs). It is a PEG-based PROTAC linker that finds applications in PROTAC synthesis [1][2].
价 格:¥电议型 号:T16598产 地:中国大陆
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T16597Propargyl-PEG2-acid;化合物 T16597Propargyl-PEG2-acid
Propargyl-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T16597产 地:中国大陆
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T16596Propargyl-PEG12-OH;化合物 T16596Propargyl-PEG12-OH
Propargyl-PEG12-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16596产 地:中国大陆
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T16595Propargyl-PEG10-Boc;化合物 T16595Propargyl-PEG10-Boc
Propargyl-PEG10-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16595产 地:中国大陆
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T16594Propargyl-PEG10-amine;化合物 T16594Propargyl-PEG10-amine
Propargyl-PEG10-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16594产 地:中国大陆
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T16593Propargyl-PEG10-acid;化合物 T16593Propargyl-PEG10-acid
Propargyl-PEG10-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16593产 地:中国大陆
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T16592Propargyl-PEG1-SS-PEG1-propargyl;化合物 T16592Propargyl-PEG1-SS-PEG1-propargyl
Propargyl-PEG1-SS-PEG1-propargyl refers to a cleavable di-functional polyethylene glycol (PEG) linker composed of two units. This specific linker is employed in the synthesis of antibody-drug conjugates (ADCs), where it plays a critical role in linking the antibody to the drug. [1]
价 格:¥电议型 号:T16592产 地:中国大陆
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T16591Propargyl-PEG1-SS-PEG1-PFP ester;化合物 T16591Propargyl-PEG1-SS-PEG1-PFP ester
Propargyl-PEG1-SS-PEG1-PFP ester is a cleavable linker consisting of a 1-unit polyethylene glycol (PEG) backbone, designed for use in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T16591产 地:中国大陆
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T16590Propargyl-PEG1-SS-PEG1-C2-Boc;化合物 T16590Propargyl-PEG1-SS-PEG1-C2-Boc
Propargyl-PEG1-SS-PEG1-C2-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T16590产 地:中国大陆
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T1659Melatonin;褪黑素Melatonine|||N-Acetyl-5-methoxytryptamine;Melatonine|||松果体素|||N-Acetyl-5-methoxytryptam
Melatonin (Melatonine) is a biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant.
价 格:¥电议型 号:T1659产 地:中国大陆
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T16559Poloxime;化合物 T16559Poloxime
Poloxime is a hydrolysis product of poloxin and is a non-ATP-competitive Plk1 inhibitor. It also has moderate Plk1 inhibitory activity.
价 格:¥电议型 号:T16559产 地:中国大陆
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T16557PNU-159682;化合物PNU-159682PNU-159682
PNU-159682 is a highly effective metabolite of the anthracycline nemorubicin. PNU-159682 has outstanding cytotoxicity. PNU-159682 is an effective ADCs cytotoxin.
价 格:¥电议型 号:T16557产 地:中国大陆