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T14572BIIE-0246;化合物 T14572AR-H 053591;AR-H 053591
BIIE-0246 is a potent and highly selective non-peptide neuropeptide Y (NPY) Y2 receptor antagonist. With an IC50 of 15 nM.
价 格:¥电议型 号:T14572产 地:中国大陆
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T14570BI 99179;化合物 T14570BI99179;BI99179
BI99179 is a potent and selective type I fatty acid synthase (FAS) inhibitor with an IC50 of 79 nM and it exhibits significant exposure (both peripheral and central) upon oral administration in rats[1].
价 格:¥电议型 号:T14570产 地:中国大陆
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T14528Benoxafos;化合物 T14528HOE 2910;HOE 2910
Benoxafos, HOE 2910, is an insecticide.
价 格:¥电议型 号:T14528产 地:中国大陆
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T14491B022化合物 B022B022|||B-022
B022 is a selective and potent NF-κB-induced kinase (NIK) inhibitor (Ki: 4.2 nM), a chemical probe for the treatment of liver inflammation and injury.B022 protects the liver from inflammation and injury caused by oxidative stress and toxins.
价 格:¥电议型 号:T14491产 地:中国大陆
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T14391Azidamfenicol;叠氮氯霉素Azidamfenicol
Azidamfenicol inhibits ribosomal peptidyltransferase with a Ki of 22 ?M. Azidamfenicol is a broad-spectrum chloramphenicol-like antibiotic.
价 格:¥电议型 号:T14391产 地:中国大陆
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T14354AVE 0991 sodium salt;化合物 T14354AVE 0991 sodium salt
AVE 0991 competes for high-affinity binding of [125I]-Ang-(1-7) to bovine aortic endothelial cell membranes, with IC50 of 21±35 nM. AVE 0991 sodium salt is a nonpeptide and orally active Ang-(1-7) receptor Mas agonist.
价 格:¥电议型 号:T14354产 地:中国大陆
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T14343Atreleuton;化合物 T14343ABT-761|||VIA-2291;ABT-761|||VIA-2291
Atreleuton (ABT-761) is a potent and selective inhibitor of leukotriene formation[1][2][3]. As a reversible and orally bioavailable 5-Lipoxygenase (5-LO) inhibitor, Atreleuton (ABT-761) exhibits selectivity.
价 格:¥电议型 号:T14343产 地:中国大陆
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T14338Atabecestat;化合物 T14338JNJ-54861911;JNJ-54861911
Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction and it is tolerated and displays a sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat (JNJ-54861911) has the potential for Alzheimer´s Disease treatment[1].
价 格:¥电议型 号:T14338产 地:中国大陆
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T1433Ritodrine hydrochloride;盐酸利托君DU21220|||Ritodrine HCl|||NSC 291565;DU21220|||盐酸利托君|||Ritodrine HCl|||
Ritodrine hydrochloride (NSC 291565) binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine hydrochloride (NSC 291565) is a phenethylamine derivative with tocolytic activity. Specifically, Ritodrine hydrochloride (NSC 291565) probably activates adenyl cyclase, thereby increasing production of cyclic adenosine monophosphate (cAMP), which in turn enhances the efflux of calcium from vasc
价 格:¥电议型 号:T1433产 地:中国大陆
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T14291Anisindione;茴茚二酮Anisindione
Anisindione is a synthetic anticoagulant and an indanedione derivative. It prevents the formation of active procoagulation factors II, VII, IX, and X, as well as the anticoagulant proteins C and S, in the liver by inhibiting the vitamin K–mediated gamma-carboxylation of precursor proteins.
价 格:¥电议型 号:T14291产 地:中国大陆
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T1428Trifluridine;曲氟尿苷NSC 529182|||Trifluorothymidine|||5-Trifluorothymidine|||NSC 75520|||Viroptic|||Tri
Trifluridine (NSC-75520) is a fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate synthase, resulting in inhibition of DNA synthesis, inhibition of protein synthesis, and apoptosis. This agent also exhibits antiviral activity.
价 格:¥电议型 号:T1428产 地:中国大陆
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T14191Alpelisib hydrochloride;化合物 T14191BYL-719 hydrochloride;BYL-719 hydrochloride
Alpelisib hydrochloride (BYL-719 hydrochloride) exhibits anticancer properties[1][2]. As a potent, selective PI3Kα inhibitor with high oral bioavailability, it demonstrates IC50 values of 5 nM for p110α, 250 nM for p110γ, 290 nM for p110δ, and 1200 nM for p110β, indicating its efficacy in targeting specific enzymes involved in cancer cell proliferation.
价 格:¥电议型 号:T14191产 地:中国大陆
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T14095ACH-806;化合物 T14095GS9132;GS9132
ACH-806 is an NS4A antagonist. It can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM.
价 格:¥电议型 号:T14095产 地:中国大陆
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T14091AC-73;化合物AC-73AC-73
AC-73 is an orally available Cluster of Differentiation 147 (CD147) inhibitor with high bioavailability that selectively disrupts the dimerization of CD147 (the binding site is in the N-terminal IgC2 domain of CD147 including Glu64 and Glu73), resulting in inhibition of the CD147/ERK1/2/STAT3/MMP-2 pathway and inhibition of liver cancer cell motility and invasion. AC-73 has antiproliferative activity and induces autophagy in leukemia cells.
价 格:¥电议型 号:T14091产 地:中国大陆
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T139911,7-Bis-Boc-1,4,7-triazaheptane;化合物 T139911,7-Bis-Boc-1,4,7-triazaheptane
1,7-Bis-Boc-1,4,7-triazaheptane is an alkyl/ether-based PROTAC linker utilized for the synthesis of PROTACs[1].
价 格:¥电议型 号:T13991产 地:中国大陆
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T139891,1,1-Trifluoroethyl-PEG4-Tos;化合物 T139891,1,1-Trifluoroethyl-PEG4-Tos
1,1,1-Trifluoroethyl-PEG4-Tos is a polyethylene glycol (PEG) derived linker molecule which offers utility in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
价 格:¥电议型 号:T13989产 地:中国大陆
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T13919Terbufibrol;特丁贝罗Terbufibrol
Terbufibrol reduces the levels of serum total cholesterol in normal and hypercholesterolemic male rats.
价 格:¥电议型 号:T13919产 地:中国大陆
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T13918Tecalcet Hydrochloride;R-568 盐酸盐R-568 hydrochloride|||R-568 (hydrochloride);R-568 盐酸盐|||R-568 hydroc
Tecalcet Hydrochloride (R-568 hydrochloride) is an allosteric and positive modulator of the calcium-sensing receptor(CaSR). Tecalcet Hydrochloride increases the sensitivity to the activation of extracellular Ca2+.
价 格:¥电议型 号:T13918产 地:中国大陆
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T13917tCFA15;化合物 T13917tCFA15
tCFA15, a trimethyl cyclohexenonic long-chain fatty alcohol with a 15-carbon atom side chain, may regulate Notch signaling and promote neuronal differentiation.
价 格:¥电议型 号:T13917产 地:中国大陆
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T13916Taurochenodeoxycholate-3-sulfate;牛磺次胆酸-3-硫酸酯Taurochenodeoxycholate-3-sulfate
Taurochenodeoxycholate-3-sulfate is a bile salt found in urine.
价 格:¥电议型 号:T13916产 地:中国大陆