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  • T360051-Oleoyl-2-Palmitoyl-rac-glycerol；1-Oleoyl-2-Palmitoyl-rac-glycerol1-Oleoyl-2-Palmitoyl-rac-glycerol

    1-Oleoyl-2-palmitoyl-rac-glycerol (1,2-OP) is a diacylglycerol containing oleic acid at the sn-1 position and palmitic acid at the sn-2 position. It enhances the inhibition of superoxide anion production by cytochalasin B when used at a concentration of 10 μM. The concentration of 1,2-OP decreases from 25.7 to 11.15% during the dry-curing process of Iberian ham.

    价 格：￥电议型 号：T36005产 地：中国大陆

  • T359724-Hydroxy-hippuric acid4-Hydroxy-hippuric acid4-Hydroxy-hippuric acid|||p-Hydroxyhippuric Acid|||par

    Polyphenol metabolite.

    价 格：￥电议型 号：T35972产 地：中国大陆

  • T35959PGPC；化合物PGPC1-Palmitoyl-2-glutaryl phosphatidylcholine；1-Palmitoyl-2-glutaryl phosphatidylcholine

    PGPC (1-Palmitoyl-2-glutaryl phosphatidylcholine) is an oxidized phospholipid and activates peroxisome proliferator-activated receptor in a concentration-dependent manner.

    价 格：￥电议型 号：T35959产 地：中国大陆

  • T35956PAz-PC；PAz-PCPAz-PC

    Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were isolated and purified from oxLDL and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position. PAz-PC is one of the predominant oxLDL species and may be one of the important structural determinants of oxLDL.

    价 格：￥电议型 号：T35956产 地：中国大陆

  • T35955PAR2 (1-6) amide (human) (trifluoroacetate salt)；PAR2 (1-6) amide (human) (trifluoroacetate salt)PAR

    PAR2 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR2 and residues 37-42 of the full-length sequence.1It binds to NCTC 2544 cells expressing human PAR2 (Ki= 9.64 μM in a radioligand binding assay) and induces calcium mobilization in the same cells (EC50= 0.075 μM).2PAR2 (1-6) amide (100 μM) reduces colony formation of A549 lung cancer cells.1It induces superoxide prod

    价 格：￥电议型 号：T35955产 地：中国大陆

  • T35928NVS-PAK1-C；NVS-PAK1-CNVS-PAK1-C；NVS-PAK1-C

    NVS-PAK1-1 is a potent allosteric inhibitor of PAK1 with an IC 50 of 5 nM for dephosphorylated PAK1 and 6 nM for phosphorylated PAK1 as assessed. Inhibition is ATP-competitive, most likely due to indirect competition due to incompatibility of ATP binding with the DFG-out binding conformation of the allosteric compound. NVS-PAK1-1 has an IC50 of 270 nM against dephosphorylated PAK2 and 720 nM against phosphorylated PAK2 respectively [1].

    价 格：￥电议型 号：T35928产 地：中国大陆

  • T35920N-methyl Paroxetine；N-methyl ParoxetineN-methyl Paroxetine

    N-methyl Paroxetine is a derivative of the selective serotonin reuptake inhibitor (SSRI) antidepressant paroxetine that inhibits [3H]paroxetine binding to rat cortical membranes (Ki = 4.3 nM). It inhibits serotonin uptake in rat brain synaptosomes with an IC50 value of 22 nM. N-methyl Paroxetine has been used as a precursor in the synthesis of paroxetine and is a potential impurity in commercial preparations of paroxetine.

    价 格：￥电议型 号：T35920产 地：中国大陆

  • T35908Paraherquamide E；Paraherquamide EParaherquamide E

    Paraherquamide E is a fungal metabolite originally isolated from P. charlesii with anthelmintic and insecticidal activities. It is lethal to C. elegans (LD50 = 6 μg/ml). Paraherquamide E is also lethal to O. fasciatus (LD50 = 0.089 μg/nymph). Oral administration of paraherquamide E (0.5-4 mg/kg) reduces T. colubriformis fecal egg count in gerbils.

    价 格：￥电议型 号：T35908产 地：中国大陆

  • T35907Paraherquamide A；Paraherquamide AParaherquamide A

    Paraherquamide A is a mycotoxin anthelmintic originally isolated from P. paraherquei. It binds to acetylcholine receptors (IC50 = 0.5 nM for head homogenates of M. domestica) and acts as an antagonist. Paraherquamide A is toxic to C. elegans (LD50 = 2.5 μg/ml) and effective against T. colubriformis infection in gerbils when used at doses ranging from 0.39 to 200 mg/kg. It is toxic to mice (LD50 = 14.9 mg/kg).

    价 格：￥电议型 号：T35907产 地：中国大陆

  • T35906Padanamide A；Padanamide APadanamide A

    Padanamide A is a bacterial metabolite originally isolated from a marine Streptomyces species. It is active against five strains of P. falciparum (EC50s = 160-340 nM), is not cytotoxic to HEK293 or HepG2 human cell lines, but is cytotoxic to Jurkat T lymphocytes with an IC50 value of approximately 60 μg/ml.

    价 格：￥电议型 号：T35906产 地：中国大陆

  • T35893rac-1,2-bis-Palmitoyl-3-chloropropanediol；rac-1,2-bis-Palmitoyl-3-chloropropanediolrac-1,2-bis-Palmi

    rac-1,2-bis-Palmitoyl-3-chloropropanediol is a 3-monochloropropane-1,2-diol (3-MCPD) ester.1It has been found as a contaminant in edible olive oils, with the lowest and highest concentrations in extra virgin and olive pomace oils, respectively.rac-1,2-bis-Palmitoyl-3-chloropropanediol has also been found in cottonseed and palm oils, as well as in shortening.2It induces renal tubular necrosis and a decrease in spermatids, but no gross pathological changes, in mice.3

    价 格：￥电议型 号：T35893产 地：中国大陆

  • T35805C16 Sphingomyelin (d18:1/16:0)；化合物 C16 Sphingomyelin (d18:1/16:0)Sphingomyelin 16:0|||N-Palmitoyl-D-

    C16 Sphingomyelin (d18:1/16:0) (N-Palmitoyl-D-sphingomyelin) is a phospholipid analog of phospholipid bilayer membranes, which can be used to study biofilm activity.

    价 格：￥电议型 号：T35805产 地：中国大陆

  • T35790Palmitic acid-1,2,3,4-13C4；Palmitic Acid-13C (C1, C2, C3, and C4 labeled)Palmitic Acid-13C (C1, C2,

    Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula

    价 格：￥电议型 号：T35790产 地：中国大陆

  • T35789Palmitic acid-1-13C；Palmitic Acid-13C (C1 labeled)Palmitic acid-1-13C

    Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.1 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.2 Palmitic acid is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.2,3,4,5,6

    价 格：￥电议型 号：T35789产 地：中国大陆

  • T35750Trypacidin；TrypacidinTrypacidin

    Trypacidin is a fungal metabolite originally isolated fromA. fumigatus.1It is active againstB. subtilisandM. bovis(MICs = 12.5 and 1.25 μg/ml, respectively), as well asT. cruziandT. gondii(MICs = 5-10 and 10-20 μg/ml, respectively).1,2It reduces viability and induces lysis of A549 human lung cancer cells (IC50s = 7.4 μM for both).3Trypacidin increases survival in a mouse model ofT. gondiiinfection when administered in six doses of 12.5 mg/kg each.1

    价 格：￥电议型 号：T35750产 地：中国大陆

  • T3575Acecainide hydrochloride；化合物Acecainide hydrochlorideASL 601|||NAPA；ASL 601|||NAPA

    Acecainide hydrochloride (NAPA) is a major metabolite of PROCAINAMIDE. Its anti-arrhythmic action may cause cardiac toxicity in kidney failure.

    价 格：￥电议型 号：T3575产 地：中国大陆

  • T35619Dapagliflozin-3-O-β-D-Glucuronide；Dapagliflozin-3-O-β-D-GlucuronideDapagliflozin-3-O-β-D-Glucuronide

    Dapagliflozin-3-O-β-D-glucuronide is a metabolite of dapagliflozin . Dapagliflozin is a first generation selective sodium glucose cotransporter (SGLT) 2 inhibitor that blocks glucose transport.[1] Dapagliflozin is metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A9 to dapagliflozin-3-O-β-D-glucuronide, which is 2,600-fold less potent than the parent compound with regard to SGLT2 inhibition.[2]

    价 格：￥电议型 号：T35619产 地：中国大陆

  • T35558KAAD-CyclopamineCyclopamine-KAADKAAD Cyclopamine|||KAADCyclopamine

    Cyclopamine-KAAD is a potent inhibitor of hedgehog signaling with an IC50 value of 20 nM in a Shh-LIGHT2 assay. It blocks binding of BODIPY-cyclopamine to cells expressing Smoothened (Smo) in a dose-dependent manner. Cyclopamine-KAAD is cell-permeable and binds to SmoA1 to promote its exit from the endoplasmic reticulum. It inhibits the invasion and migration (45.9 and 43.3% inhibition, respectively) of Bel-7402 hepatocarcinoma cells and decreases the expression of nuclear glioma-associated onco

    价 格：￥电议型 号：T35558产 地：中国大陆

  • T3551D-Pantothenic acid hemicalcium salt；泛酸钙D-Pantothenic Acid Calcium|||Calpanate|||Calcium D-pantothena

    D-Pantothenic acid hemicalcium salt (Calcium pantothenate), a kind of water soluble vitamin, can reduce the patulin content of the apple juice.

    价 格：￥电议型 号：T3551产 地：中国大陆

  • T35497(±)7(8)-EpDPA；(±)7(8)-EpDPA(±)7(8)-EpDPA

    Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina. (±)7(8)-EpDPA is an epoxide derivative of DHA that is generated by the action of cytochrome P450 epoxygenases. It is naturally occurring in plasma and brain and spinal cord tissues and is increased following dietary supplementation with ω-3 fatty acids. (±)7(8)-EpDPA and other epoxy metabolites of DHA modulate receptor and channel activities to evoke diverse effects, such as promoting

    价 格：￥电议型 号：T35497产 地：中国大陆

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