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T21853(E)-AG 556;化合物(E)-AG 556(E)-AG 556
AG 556 is a selective inhibitor of EGFR and blocks LPS-induced TNF-α production.
价 格:¥电议型 号:T21853产 地:中国大陆
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T21768PF-562271 hydrochloride化合物PF-562271 HClPF-562271 HCl
PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
价 格:¥电议型 号:T21768产 地:中国大陆
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T21756Bizine;化合物 T21756Bizine
Bizine, a Phenelzine analogue, is a potent and selective LSD1 inhibitor, with a b>K i of 59 nM. Bizine can modulate bulk histone methylation in cancer cells. Bizine has potential applications in neuroprotective [1].
价 格:¥电议型 号:T21756产 地:中国大陆
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T215691-(1-Naphthyl) piperazine hydrochloride;化合物T215691-naphthalen-1-ylpiperazine hydrochloride|||1-(Naph
1-(1-Naphthyl) piperazine hydrochloride (1-naphthalen-1-ylpiperazine hydrochloride) is a serotonergic ligand which could bind nonselectively with multiple serotonin (5-HT) receptors.
价 格:¥电议型 号:T21569产 地:中国大陆
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T21567LCyclosomatostatin Acetate;化合物Cyclosomatostatin AcetateCyclosomatostatin Acetate (84211-54-1 Free bas
Cyclosomatostatin Acetate is an effective antagonist of the somatostatin receptor.Cyclosomatostatin Acetate inhibits SSTR1 signaling and decreases cell proliferation, ALDH+ cell population size, and sphere-formation in colorectal cancer cells.
价 格:¥电议型 号:T21567L产 地:中国大陆
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T21561WAY-100635;化合物 T21561WAY-100635
WAY-100635 is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC50 of 0.91 nM and Ki of 0.39 nM. It exhibits pIC50 values of 8.9 and 6.6 for 5-HT1A and α1-adrenergic receptors, respectively. Moreover, WAY-100635 acts as a potent agonist of the dopamine D4 receptor [1] [2] [3].
价 格:¥电议型 号:T21561产 地:中国大陆
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T2156WP1066;化合物WP1066WP1066
WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3. WP1066 has been used in trials studying the treatment of Melanoma, Brain Cancer, Solid Tumors, and Central Nervous System Neoplasms.
价 格:¥电议型 号:T2156产 地:中国大陆
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T21556Hydroxytacrine maleate;维吖啶马来酸盐Velnacrine maleate|||HP 029 maleate;Velnacrine maleate|||HP 029 maleat
Hydroxytacrine maleate (Velnacrine maleate) is a cholinesterase (cholinesterase) inhibitor that enhances memory in rodents and may be used in the study of Alzheimer´s dementia of the Alzheimer type (SDAT).
价 格:¥电议型 号:T21556产 地:中国大陆
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T21456Grazoprevir hydrate;化合物 T21456Grazoprevir|||MK5172|||MK 5172|||MK-5172;Grazoprevir|||MK5172|||MK 517
Grazoprevir, a second generation hepatitis C virus protease inhibitor acting at the NS3/4a protease targets, has good activity against a range of hepatitis C virus genotype variants, including some that are resistant to most currently used antiviral medications.
价 格:¥电议型 号:T21456产 地:中国大陆
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T21410Triptorelin acetate(57773-63-4 free base);醋酸曲普瑞林Wy 42422|||Triptorelin Acetate|||CL 118532|||AY 2565
Triptorelin acetate(57773-63-4 free base) (CL 118,532) is used as a GnRH agonist. It decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by causing constant stimulation of the pituitary. Triptorelin acetate(57773-63-4 free base) may be used in the treatment of hormone-responsive cancers such as breast cancer or prostate cancer, precocious puberty, estrogen-dependent conditions, and assisted reproduction.
价 格:¥电议型 号:T21410产 地:中国大陆
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T21400Cefotetan disodium;化合物 T21400YM09330|||YM-09330|||ICI-156834|||ICI 156834|||YM 09330|||Cefotetan Sod
Cefotetan Sodium, a second-generation cephalosporin, cephamycin antibiotic, is active against a wide range of both aerobic and anaerobic gram-negative and gram-positive bacteria. Cefotetan disrupts the cell wall synthesis by binding to penicillin-binding proteins.
价 格:¥电议型 号:T21400产 地:中国大陆
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T21394Sarecycline hydrochloride;化合物 T21394P005672|||P-005672|||WC-3035|||WC 3035|||Sarecycline HCl|||WC303
Sarecycline, a novel and tetracycline-derived antibiotic, is being developed for use as an oral once daily antibiotic treatment for patients suffering from moderate to severe acne vulgaris. Sarecycline has anti-inflammatory activity and the potential for a favorable tolerability profile.
价 格:¥电议型 号:T21394产 地:中国大陆
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T213564-(Trifluoromethyl)phenylboronic acid;化合物 T213564-(Trifluoromethyl)phenylboronic acid
4-(Trifluoromethyl)benzeneboronic acid is used to N-arylate imidazoles and amines with copper-exchanged fluorapatite, as well as used in microwave-promoted cross-coupling with acid chlorides leading to aryl ketones.
价 格:¥电议型 号:T21356产 地:中国大陆
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T21309Nafarelin acetate(76932-56-4 free base);醋酸萘法瑞林RS-94991-298|||Nafarelin acetate|||Nafarelin acetate h
Nafarelin acetate(76932-56-4 free base) (RS-94991-298) is a GnRH agonist that acts as an analog of GnRH. Nafarelin acetate(76932-56-4 free base) causes a decrease in the pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It may be used in the treatment of estrogen-dependent conditions.
价 格:¥电议型 号:T21309产 地:中国大陆
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T21302LUNC 569 hydrochloride;化合物UNC 569 hydrochlorideUNC 569 hydrochloride (1350547-65-7 Free base);UNC 569
UNC 569 hydrochloride is a reversible and ATP-competitive inhibitor of Mer with an IC50 of 2.9 nM and a Ki of 4.3 nM. UNC 569 hydrochloride inhibits Axl and Tyro3 with IC50s of 37 nM and 48 nM, respectively. UNC 569 hydrochloride can be used in studies about acute lymphoblastic leukemia and atypical teratoid/rhabdoid tumors.
价 格:¥电议型 号:T21302L产 地:中国大陆
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T21302UNC569;化合物UNC569UNC 569;UNC 569
UNC569 (UNC 569) is a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the body. It is also a selective uric acid re-absorption inhibitor. UNC569 could normalize the amount of uric acid excreted by gout patients previously classified as under-excretors.
价 格:¥电议型 号:T21302产 地:中国大陆
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T21256Algestone;化合物 T21256Alphasone;Alphasone
Algestone is a synthetic progestational dihydroxy derivative with anti-inflammatory properties.
价 格:¥电议型 号:T21256产 地:中国大陆
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T21165Pellitorine;墙草碱AI3-19560|||Pellitorin;AI3-19560|||墙草碱|||Pellitorin
Pellitorine (Pellitorin) is an extract of Tetradium daniellii, and acts as a TRPV1 antagonist.
价 格:¥电议型 号:T21165产 地:中国大陆
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T21156Hydrocinchonine;化合物 T21156Dihydrocinchonine;Dihydrocinchonine
Hydrocinchonine is an Alkaloid from Olea europaea and is found in fruits.
价 格:¥电议型 号:T21156产 地:中国大陆
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T21094Pseudopelletierine free base;化合物 T21094NSC 116056|||Granatonine|||Pseudopelletierine|||Granatan-3-on
Pseudopelletierine is the main alkaloid derived from the root-bark of Punica granatum, along with at least three other alkaloids: isopelletierine, methylpelleteirine (C9H17ON) and pelletierine, which yield 1.8, 0.01, 0.20 and 0.52 grams per kilogram of raw bark.
价 格:¥电议型 号:T21094产 地:中国大陆