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T14175Aldose reductase-IN-1Aldose reductase-IN-1
Aldose reductase-IN-1 is a aldose reductase inhibitor (IC50: 28.9 pM).
价 格:¥电议型 号:T14175产 地:美洲
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T14283amyloid P-IN-1amyloid P-IN-1
amyloid P-IN-1 is used research of diseases or disorders wherein depletion of serum amyloid P component (SAP). Which including Alzheimer´s disease, amyloidosis, osteoarthritis, and type 2 diabetes mellitus.
价 格:¥电议型 号:T14283产 地:美洲
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T14763BoNT-IN-1BoNT-IN-1
BoNT-IN-1 is a potent inhibitor of Botulinum neurotoxin A light chain (BoNTA LC) with IC50 of 0.9 uM. IC50 value: 0.9 uM Target: BoNT in vitro: BoNT-IN-1 targets BoNT/A LC enzymatic activity. Which is highly efficient in vitro, BoNT-IN-1 has good property
价 格:¥电议型 号:T14763产 地:美洲
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T14860CaMKII-IN-1CaMKII-IN-1
CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor (IC50: 63 nM). It has significantly high selectivity against CaMKIV, MLCK, p38a, Akt1, and PKC.
价 格:¥电议型 号:T14860产 地:美洲
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T15109DGAT1-IN-1DGAT1-IN-1
DGAT1-IN-1 is a potent inhibitor of DGAT1 (IC50 of < 10 nM) (cell lysate from Hep3B cells overexpressing human DGAT1).
价 格:¥电议型 号:T15109产 地:美洲
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T15274FEN1-IN-1FEN1-IN-1
FEN1-IN-1 is an inhibitor of flap endonuclease 1 (FEN1). FEN1-IN-1 binds to the active site of FEN1. It partly achieves inhibition by the co-ordination of Mg2+ ions.
价 格:¥电议型 号:T15274产 地:美洲
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T15413GPR120-IN-1GPR120-IN-1
GPR120-IN-1 is a selective agonist of Gpr120 ( logEC50: ?7.62).
价 格:¥电议型 号:T15413产 地:美洲
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T15482HIF-2α-IN-1HIF-2α-IN-1
HIF-2α-IN-1 is an inhibitor of HIF-2α. In HIF-2α scintillation proximity assay, It also has an IC50 of less than 500 nM.
价 格:¥电议型 号:T15482产 地:美洲
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T15605JAK/HDAC-IN-1JAK/HDAC-IN-1
JAK/HDAC-IN-1 is an effective JAK2/HDAC dual inhibitor. JAK/HDAC-IN-1 has an IC50s of 4 and 2 nM for JAK2 and HDAC, respectively. It also shows antiproliferative and proapoptotic activities in several hematological cell lines.
价 格:¥电议型 号:T15605产 地:美洲
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T15607JAK3-IN-1JAK3-IN-1
JAK3-IN-1 displays over 180-fold more selective for JAK3 than JAK1 (IC50 of 896 nM) and JAK2 (IC50 of 1050 nM). JAK3-IN-1 is a selective and orally active JAK3 inhibitor (IC50: 4.8 nM).
价 格:¥电议型 号:T15607产 地:美洲
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T15649KDM5-IN-1KDM5-IN-1
KDM5-IN-1 is an effective, selective, and orally bioavailable inhibitor of KDM5 (IC50: 15.1 nM).
价 格:¥电议型 号:T15649产 地:美洲
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T15650KDM5A-IN-1KDM5A-IN-1
KDM5A-IN-1 is obviously less effective against other KDM5B enzymes (1A, 2B, 3B, 4C, 6A, 7B). KDM5A-IN-1 is a potent and orally bioavailable inhibitor of pan-histone lysine demethylases 5 (IC50s: 45 nM, 56 nM, and 55 nM for KDM5A, KDM5B, and KDM5C, respect
价 格:¥电议型 号:T15650产 地:美洲
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T15659KHK-IN-1 hydrochlorideKHK-IN-1 hydrochloride
KHK-IN-1 hydrochloride is a potent inhibitor of ketohexokinase (KHK) (IC50: 12 nM). In the ATP-binding region of KHK, KHK-IN-1 hydrochloride interacts with Asp-27B.
价 格:¥电议型 号:T15659产 地:美洲
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T15661Kif15-IN-1Kif15-IN-1
Kif15-IN-1 is an inhibitor of the mitotic Kinesin family member 15 (Kif15). Kif15-IN-1 is used for the research of cellular proliferative diseases.
价 格:¥电议型 号:T15661产 地:美洲
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T15782Lp-PLA2 -IN-1Lp-PLA2 -IN-1
Lp-PLA2 -IN-1 suppresses Lp-PLA2 activity processes for their preparation. Lp-PLA2 -IN-1also inhibits to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example, atherosclerosis, Alzh
价 格:¥电议型 号:T15782产 地:美洲
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T16007MALAT1-IN-1MALAT1-IN-1
MALAT1-IN-1 modulated Malat1 downstream genes in a dose-dependent manner without affecting the expression of nuclear enriched abundant transcript 1 (Neat1). MALAT1-IN-1 is an effective and specific Malat1 inhibitor.
价 格:¥电议型 号:T16007产 地:美洲
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T16027Mcl1-IN-1Mcl1-IN-1
Mcl1-IN-1 is a myeloid cell factor 1 inhibitor (IC50=2.4 ?M).
价 格:¥电议型 号:T16027产 地:美洲
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T16078Mirk-IN-1Mirk-IN-1,Dyrk1B/A-IN-1,
Mirk-IN-1 is an effective inhibitor of Dyrk1B(Mirk kianse) and Dyrk1A (IC50: 68±48 nM and 22±8 nM respectively).
价 格:¥电议型 号:T16078产 地:美洲
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T16162Mutated EGFR-IN-1Mutated EGFR-IN-1,Osimertinib analog,
Mutated EGFR-IN-1 is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant, and T790M resistance mutant.
价 格:¥电议型 号:T16162产 地:美洲
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T16424p38 MAPK-IN-1p38 MAPK-IN-1
p38 MAPK-IN-1 displays sustained levels, low clearance, and good bioavailability. p38 MAPK-IN-1 is a novel effective and selective inhibitor of p38 MAPK (IC50: 68 nM).
价 格:¥电议型 号:T16424产 地:美洲