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T13058T025;化合物T025T025
T025 is a pan CLK inhibitor with Kds of 4.8, 0.096, 6.5, 0.61, and 0.074 nM for CLK1-4, respectively. T025 displays anti-proliferative activities with IC50s of 30-300 nM in hematological and solid cancer cell lines. T025 can be used in studies about MYC-driven diseases.
价 格:¥电议型 号:T13058产 地:中国大陆
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T12872SDZ 220-581 Ammonium salt化合物 T12872SDZ 220581 Ammonium salt|||SDZ 220 581 Ammonium salt|||SDZ 220-58
SDZ 220-581 Ammonium salt is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).
价 格:¥电议型 号:T12872产 地:中国大陆
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T126058Parsonsianine;化合物 ParsonsianineParsonsianine
Parsonsianine is a useful organic compound for research related to life sciences and the catalog number is T126058.
价 格:¥电议型 号:T126058产 地:中国大陆
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T125058Heliosupine N-oxide;化合物 Heliosupine N-oxideHeliosupine N-oxide
Heliosupine N-oxide is a useful organic compound for research related to life sciences and the catalog number is T125058.
价 格:¥电议型 号:T125058产 地:中国大陆
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T1240583,4-Di-O-galloylquinic acid;化合物 3,4-Di-O-galloylquinic acid3,4-Di-O-galloylquinic acid
3,4-Di-O-galloylquinic acid is a useful organic compound for research related to life sciences. The catalog number is T124058 and the CAS number is 86687-37-8.
价 格:¥电议型 号:T124058产 地:中国大陆
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T12058MK2-IN-3 hydrate;化合物MK-2 Inhibitor IIIMK-2 Inhibitor III;MK-2 Inhibitor III
MK2-IN-3 hydrate (MK-2 Inhibitor III) is an orally active, selective, and ATP-competitive inhibitor of MAPKAP-K2 (MK-2) (IC50 of 0.85 nM)
价 格:¥电议型 号:T12058产 地:中国大陆
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T11338Furamidine;化合物 T11338DB75|||NSC 305831;DB75|||NSC 305831
Furamidine is also a selective and cell-permeable protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 of 9.4 μM. Furamidine is selective for PRMT1 over PRMT5, PRMT6, and PRMT4 (CARM1) (IC50s of 166 μM, 283 μM, and >400 μM, respectively). Furamidine (DB75) is abisbenzamidine derivative and an antiparasite agent. Furamidine is a potent, reversible and competitive tyrosyl-DNA phosphodiesterase 1 (TDP-1) inhibitor. Inhibition of TDP-1 by Furamidine is effective both with single- and
价 格:¥电议型 号:T11338产 地:中国大陆
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T11058DM3;化合物 T11058Maytansinoid DM3;Maytansinoid DM3
DM3 (Maytansinoid DM3) is a maytansine mimic containing disulfide or thiol groups and a tubulin inhibitor. It is the cytotoxic part of antibody-drug conjugates (ADCs) .
价 格:¥电议型 号:T11058产 地:中国大陆
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T10589LBPN-15606;化合物 T10589LBPN-15606
BPN-15606, an orally active γ-secretase modulator (GSM), significantly reduces Aβ42 and Aβ40 production in SHSY5Y neuroblastoma cells, demonstrating IC50 values of 7 nM and 17 nM, respectively. This compound exhibits favorable pharmacokinetic/pharmacodynamic (PK/PD) properties, such as bioavailability, half-life, and clearance. Importantly, BPN-15606 markedly decreases Aβ42 and Aβ40 levels in the central nervous system of both rats and mice[1].
价 格:¥电议型 号:T10589L产 地:中国大陆
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T10589BPN-15606 besylate (1914989-49-3 free base);化合物 T10589BPN-15606 besylate;BPN-15606 besylate
BPN-15606 besylate is a highly potent, orally active γ-secretase modulator, attenuates the production of Aβ40 and Aβ42 by SHSY5Y neuroblastoma cells (IC50s: 7 nM and 17nM).
价 格:¥电议型 号:T10589产 地:中国大陆
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T10588BPI-9016M;化合物 T10588BPI-9016M
BPI-9016M is an effective, orally active, and selective dual inhibitor of c-Met and AXL tyrosine kinases. It suppresses tumor cell growth, invasion, and migration of lung adenocarcinoma.
价 格:¥电议型 号:T10588产 地:中国大陆
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T10587BPH-652;化合物 T10587BPH-652
BPH-652 is an S. aureus dehydrosqualene synthase (CrtM) inhibitor (Ki: 1.5 nM; IC50: 100-300 nM for S. aureus pigment formation).
价 格:¥电议型 号:T10587产 地:中国大陆
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T10586LBPH-1358;化合物BPH-1358NSC50460;NSC50460
BPH-1358 (NSC-50460) (NSC-50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. With IC50s of 1.8 μM and 110 nM, respectively. And it is active against S. aureus in vitro (MIC ~250 ng/mL)[1][2].
价 格:¥电议型 号:T10586L产 地:中国大陆
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T10586BPH-1358 free base;化合物 T10586NSC50460 free base;NSC50460 free base
BPH-1358 (NSC50460) free base is a potent human undecaprenyl diphosphate synthase (UPPS) and farnesyl diphosphate synthase (FPPS) inhibitor (IC50s: 110 nM and 1.8 μM) and is active against S. aureus in vitro (MIC ~250 ng/mL).
价 格:¥电议型 号:T10586产 地:中国大陆
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T10585Bozitinib;化合物BozitinibCBT-101|||PLB-1001;CBT-101|||PLB-1001
Bozitinib (PLB-1001) (PLB-1001) is a highly selective inhibitor of the c-MET kinase with blood-brain barrier permeability. Bozitinib binds to the conventional ATP-binding pocket of the tyrosine kinase superfamily.
价 格:¥电议型 号:T10585产 地:中国大陆
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T10584Bovinic acid;9Z,11E十八碳二烯酸(9Z,11E)-Octadecadienoic acid|||Rumenic acid;(9Z,11E)-Octadecadienoic acid|
Bovinic acid ((9Z,11E)-Octadecadienoic acid) is a conjugated linoleic acid with anticancer and anti-atherosclerotic activity and can be used to study coronary heart disease and obesity in the elderly.
价 格:¥电议型 号:T10584产 地:中国大陆
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T10582Borrelidin;化合物 T10582Treponemycin;Treponemycin
Borrelidin (Treponemycin) is a bacterial and eukaryal threonyl-tRNA synthetase inhibitor. It is a macrolide antibiotic isolated from Streptomyces rochei.
价 格:¥电议型 号:T10582产 地:中国大陆
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T10581Boc-MLF TFA (67247-12-5 free base);化合物 T10581Boc-Met-Leu-Phe-OH (TFA)|||Boc-MLF TFA;Boc-Met-Leu-Phe-
Boc-MLF (TFA) is a specific antagonist of formyl peptide receptor (FPR) and also inhibits signaling through FPRL1 at higher concentrations.
价 格:¥电议型 号:T10581产 地:中国大陆
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T10580BOC-D-FMK;3-[[叔丁氧羰基]氨基]-5-氟-4-氧代戊酸甲酯BOC-D-FMK
Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 μM).
价 格:¥电议型 号:T10580产 地:中国大陆
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T1058Carboplatin;卡铂NSC 241240|||CBDCA|||JM-8;NSC 241240|||卡铂|||CBDCA|||JM-8
Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor. Carboplatin binds to DNA, inhibits replication and transcription, and induces cell death. Carboplatin has antitumor activity.
价 格:¥电议型 号:T1058产 地:中国大陆