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T69477F81-1144b;化合物 F81-1144bF81-1144b
F81-1144b is a matrix metalloproteinase inhibitor which reduces secretion of very low density lipoprotein-triacylglycerol, thereby lowering TAG levels in serum and the liver. F81-1144b also lowers VLDL-TAG secretion, de novo FA synthesis in the liver, and serum levels of insulin and glucose.
价 格:¥电议型 号:T69477产 地:中国大陆
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T69114Nutlin-2;化合物 Nutlin-2Nutlin-2
Nutlin-2 is a potent and selective p53-MDM2 binding inhibitor.
价 格:¥电议型 号:T69114产 地:中国大陆
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T6905Netupitant;奈妥吡坦Ro 67-31898/000|||CID 6451149;Ro 67-31898/000|||奈妥吡坦|||CID 6451149
Netupitant (CID 6451149) is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM).
价 格:¥电议型 号:T6905产 地:中国大陆
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T68114LNardeterol HCl;那地特罗盐酸盐Nardeterol HCl(73865-18-6 Free base);Nardeterol HCl(73865-18-6 Free base)
Nardeterol HCl is a β-adrenergic receptor partial agonist used in the study of the central nervous system.CAS ??13460-73-83-4
价 格:¥电议型 号:T68114L产 地:中国大陆
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T68114nardeterol;化合物 nardeterolnardeterol
Nardeterol is a high-affinity, partial agonist for beta adrenergic receptors.
价 格:¥电议型 号:T68114产 地:中国大陆
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T68037LCBS-1114 HCl;CBS-1114盐酸盐N-Phenylbenzamidrazone hydrochloride|||cbs-1114 HCl(46721-85-1 Free base);N-
CBS-1114 HCl (N-Phenylbenzamidrazone hydrochloride) is a 5-lipoxygenase inhibitor and an anti-inflammatory compound in a good eye-permeable model.CBS-1114 HCl maintains and improves cardiac function, attenuates cardiac dysfunction, as well as reduces epicardial adipose tissue and/or pericardial adipose tissue in subjects with cardiovascular disease.
价 格:¥电议型 号:T68037L产 地:中国大陆
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T6763Xevinapant;化合物AT406ARRY-334543|||SM-406|||AT406|||Debio-1143;ARRY-334543|||SM-406|||AT406|||Debio-11
Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide. Phase 1.
价 格:¥电议型 号:T6763产 地:中国大陆
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T67114Oleyl Bromide;化合物 Oleyl BromideOleyl Bromide
Oleyl Bromide is a useful organic compound for research related to life sciences and the catalog number is T67114.
价 格:¥电议型 号:T67114产 地:中国大陆
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T661147-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine;化合物 7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine7-Bromopy
7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine is a useful organic compound for research related to life sciences. The catalog number is T66114 and the CAS number is 937046-98-5.
价 格:¥电议型 号:T66114产 地:中国大陆
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T65114Dihexadecyl hydrogen phosphate;化合物 Dihexadecyl PhosphateDihexadecyl hydrogen phosphate
Dihexadecyl hydrogen phosphate is a useful organic compound for research related to life sciences. The catalog number is T65114 and the CAS number is 2197-63-9.
价 格:¥电议型 号:T65114产 地:中国大陆
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T6455CP-91149;化合物CP91149CP-91149
CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose.
价 格:¥电议型 号:T6455产 地:中国大陆
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T64114SPH5030;化合物 SPH5030SPH5030
SPH5030 is an irreversible, selective inhibitor of HER2. SPH5030 inhibits HER2WT (IC50: 3.51 nM), EGFRWT (IC50: 8.13 nM). SPH5030 can be used in cancer research.
价 格:¥电议型 号:T64114产 地:中国大陆
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T63746Vamotinib;化合物 VamotinibPF-114;PF-114
Vamotinib (PF-114) is an orally active and specific tyrosine kinase inhibitor with antiproliferative and antitumour activity.Vamotinib inhibits the phosphorylation of BCR/ABL and BCR/ABL-T315I, which promotes apoptosis. Vamotinib is used to study drug-resistant Philadelphia chromosome-positive (Ph+) leukaemia and Alzheimer´s disease.
价 格:¥电议型 号:T63746产 地:中国大陆
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T63516NRX-252114;化合物NRX-252114NRX252114|||NRX 252114;NRX252114|||NRX 252114
NRX-252114 (NRX252114) induces degradation of mutant β-catenin NRX-252114 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP, and is able to enhance the binding of pSer33/S37A β-catenin to β-TrCP with an EC50 of 6.5 nM and a Kd of 0.4 nM. Kd is 0.4 nM.
价 格:¥电议型 号:T63516产 地:中国大陆
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T63114ALK5-IN-7;化合物 ALK5-IN-7ALK5-IN-7
ALK5-IN-7 is an effective inhibitor of ALK5. Transforming growth factor β (TGF-β) is a multifunctional cytokine that is involved in regulating cell proliferation, differentiation, and apoptosis through autocrine, paracrine, and endocrine pathways using complex receptor signaling pathways on the cell surface. ALK5-IN-7 has the potential to perform research on TGF-β-related diseases and conditions (including but not limited to tumor, fibrosis, inflammatory diseases, autoimmune diseases, etc.).
价 格:¥电议型 号:T63114产 地:中国大陆
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T6279214α-Demethylase/DNA Gyrase-IN-1;化合物 14α-Demethylase/DNA Gyrase-IN-114α-Demethylase/DNA Gyrase-IN-1
14α-Demethylase/DNA Gyrase-IN-1 (Compound 7c) is a potent inhibitor of 14α-Demethylase/DNA Gyrase with antibacterial activity.
价 格:¥电议型 号:T62792产 地:中国大陆
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T62114JAK3-IN-12;化合物 JAK3-IN-12JAK3-IN-12
JAK3-IN-12 (compound 15k) is a potent inhibitor of JAK3 (IC50: 9.5 nM) and can be used in the study of rheumatoid arthritis.
价 格:¥电议型 号:T62114产 地:中国大陆
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T61177NSC114126;化合物 NSC114126NSC114126
NSC114126 is a highly effective and orally bioavailable inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR-TK). This compound exhibits robust antiproliferative properties, making it a promising candidate for further investigation in the field of cancer research [1].
价 格:¥电议型 号:T61177产 地:中国大陆
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T61149Antibacterial agent 121;化合物 Antibacterial agent 121Antibacterial agent 121
Antibacterial agent 121 (Compound 10) demonstrates antibacterial properties and exhibits efficacy against mycobacterial strains while also possessing anti-inflammatory activity. This compound finds potential applications in Tuberculosis (TB) research [1].
价 格:¥电议型 号:T61149产 地:中国大陆
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T61148Flutrimazole;氟曲马唑Flutrimazole
Flutrimazole is a dual-action imidazole antifungal compound, exhibiting both anti-inflammatory and antifungal properties. Notably, flutrimazole demonstrates limited transdermal penetration, making it particularly advantageous for topical applications in the treatment of fungal infections, especially those accompanied by inflammation.
价 格:¥电议型 号:T61148产 地:中国大陆