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T18721MAC-VC-PABC-ST7612AA1;化合物 T18721MAC-VC-PABC-ST7612AA1
MAC-VC-PABC-ST7612AA1 is a part of antibody drug conjugates (ADCs) charged with HDAC inhibitor by a linker, shows antitumor activity[1].
价 格:¥电议型 号:T18721产 地:中国大陆
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T17721Cbz-NH-PEG24-C2-acid;化合物 T17721Cbz-NH-PEG24-C2-acid
Cbz-NH-PEG24-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17721产 地:中国大陆
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T1747LTedizolid phosphate disodium salt;化合物 T1747LTorezolid phosphate sodium salt|||DA 7218|||TR-701|||TR
Tedizolid phosphate is a novel antibacterial prodrug. Tedizolid phosphate is a next-generation oxazolidinone with activity against both methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus spp. It also has effective activity against Gram-positive pathogens.
价 格:¥电议型 号:T1747L产 地:中国大陆
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T17472Azide-PEG9-amido-C16-Boc;化合物 T1747217-(Azide-PEG9-ethylcarbamoyl)heptadecanoic t-butyl ester;17-(Azi
Azide-PEG9-amido-C16-Boc is an alkyl/ether-based PROTAC linker with utility in PROTAC synthesis [1].
价 格:¥电议型 号:T17472产 地:中国大陆
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T17219Vatalanib free base;瓦他拉尼碱Vatalanib free base
Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).
价 格:¥电议型 号:T17219产 地:中国大陆
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T17218Varespladib methyl;化合物Varespladib methylA-002|||LY333013;A-002|||LY333013
Varespladib methyl (LY333013), a bioavailable prodrug of Varespladib, is a selective group II secretory phospholipase A2 inhibitor.
价 格:¥电议型 号:T17218产 地:中国大陆
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T17217Vamorolone;地塞米松EP杂质EVBP15;地塞米松EP杂质E|||VBP15
Vamorolone (VBP15) is an orally active dissociative steroidal anti-inflammatory drug and membrane-stabilizer. Vamorolone improves muscular dystrophy without side effects. Vamorolone displays effective NF-κB inhibition and substantially decreases hormonal effects.
价 格:¥电议型 号:T17217产 地:中国大陆
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T17216Valspodar;伐司扑达PSC 833;PSC 833
Valspodar (PSC 833) is a specific P-glycoprotein inhibitor and MDR regulator often used as a chemical sensitizer to study advanced epithelial ovarian cancer.
价 格:¥电议型 号:T17216产 地:中国大陆
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T17215Valnoctamide化合物 T17215Valmethamide
Valnoctamide inhibits benzodiazepine-refractory status epilepticus. Valnoctamide acts directly on GABAA receptors.
价 格:¥电议型 号:T17215产 地:中国大陆
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T17214Valencene;凡伦橘烯(NSC 148969|||NSC-148969|||NSC148969;NSC 148969|||NSC-148969|||NSC148969
Valencene (NSC-148969) is a sesquiterpenoid isolated from Cyperus rotundus and is an aroma component of citrus fruits and citrus-derived odors.ValenceneValencene has anti-allergic, anti-inflammatory, anti-melanogenic, and antioxidant activities. Valencene inhibits the overexpression of Th2 chemokines and pro-inflammatory chemokines by blocking the NF-κB pathway.
价 格:¥电议型 号:T17214产 地:中国大陆
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T17213Val-cit-PAB-OH;化合物Val-cit-PAB-OHVal-cit-PAB-OH
Val-cit-PAB-OH is an ADC linker that is cleavable.
价 格:¥电议型 号:T17213产 地:中国大陆
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T17212VAL-083;去水卫矛醇Dianhydrogalactitol|||Dianhydrodulcitol;1,2:5,6-二脱水半乳糖醇|||Dianhydrogalactitol|||去水卫矛醇||
VAL-083 (Dianhydrogalactitol) is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.
价 格:¥电议型 号:T17212产 地:中国大陆
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T17211Vafidemstat;化合物 VafidemstatORY-2001;ORY-2001
Vafidemstat (ORY-2001) is a selective, orally active lysyl-histone demethylase (LSD1)/MAO-B inhibitor that crosses the blood-brain barrier for the study of neurological diseases.
价 格:¥电议型 号:T17211产 地:中国大陆
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T17210L1(3R,6R)-Vaborbactam(3R,6R)-法硼巴坦(3R,6R)-RPX7009|||(3R,6R)-Vaborbactam (Iso-1360457-46-0)
(3R,6R)-Vaborbactam ((3R,6R)-Vaborbactam (Iso-1360457-46-0)) is a cyclic boronic acid pharmacophore β-lactamase inhibitor with potential antimicrobial activity. (S)-Vamicamide ((S)-Vamicamide (Iso-132373-81-0)) is a novel anticholinergic compound.
价 格:¥电议型 号:T17210L1产 地:中国大陆
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T17210LVaborbactam ammonium salt;法硼巴坦铵盐RPX7009 ammonium salt|||Vaborbactam ammonium salt(1360457-46-0 Free
Vaborbactam ammonium salt is a β-lactamase inhibitor that restores carbapenem activity against KPC-producing strains and is often used in conjunction with other drugs to study fungal infections.
价 格:¥电议型 号:T17210L产 地:中国大陆
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T17210Vaborbactam;法硼巴坦RPX7009;RPX7009
Vaborbactam (RPX7009) is a β-lactamase inhibitor that is often used in conjunction with meropenem to study pneumonia and CRE infections.
价 格:¥电议型 号:T17210产 地:中国大陆
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T16721Ralimetinib;化合物 T16721LY2228820;LY2228820
Ralimetinib selectively inhibits phosphorylation of MK2 (Thr334) and has no effect on phosphorylation of p38α MAPK, JNK, ERK1/2, c-Jun, ATF2, or c-Myc. Ralimetinib is an effective and selective, ATP-competitive inhibitor of p38 MAPK α/β (IC50s: 5.3 and 3.2 nM, respectively).
价 格:¥电议型 号:T16721产 地:中国大陆
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T15721Latrunculin A;化合物 T15721LAT-A;LAT-A
Latrunculin A is a toxin isolated from the red sea sponge Latrunculia magnifica. Latrunculin A binds to actin monomers and it also inhibits polymerization of actin (Kds: 0.1, 0.4, 4.7 μM, and 0.19 μM for ATP-actin, ADP-Pi-actin, ADP-actin, and G-actin, respectively).
价 格:¥电议型 号:T15721产 地:中国大陆
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T1488Procarbazine hydrochloride;盐酸甲基苄肼NSC-77213 HCl|||Procarbazine HCl;NSC-77213 HCl|||盐酸甲基苄肼|||Procarbaz
Procarbazine hydrochloride (NSC-77213 HCl) is the hydrochloride salt of a methylhydrazine derivative with antineoplastic and mutagenic activities. Although the exact mode of cytotoxicity has not been elucidated, procarbazine, after metabolic activation, appears to inhibit the trans-methylation of methionine into transfer RNA (t-RNA), thereby preventing protein synthesis and consequently DNA and RNA synthesis. This agent may also undergo auto-oxidation, resulting in the formation of cytotoxic fre
价 格:¥电议型 号:T1488产 地:中国大陆
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T14721Boc-Aminooxy-PEG4-Tos;化合物 T14721Boc-Aminooxy-PEG4-Tos
Boc-Aminooxy-PEG4-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14721产 地:中国大陆