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T14511BAY1082439BAY1082439
BAY1082439 is a selective and orally bioavailable inhibitor of PI3Kα/β/δ, and also inhibits mutated forms of PIK3CA, with highly effective in inhibiting Pten-null prostate cancer growth.
价 格:¥电议型 号:T14511产 地:美洲
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T14878CAY10566CAY10566
CAY10566 shows excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-CoAs (LCFA-CoAs) to monounsaturated LCFA-CoAs in HepG2 cells (IC50=7.9 nM or 6.8 nM). CAY10566 is a potent, orally bioavailable and selective stearoy
价 格:¥电议型 号:T14878产 地:美洲
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T1500Xylazine hydrochlorideXylazine hydrochloride,BAY 1470 hydrochloride,Xylazine HCl
Xylazine hydrochloride is an adrenergic alpha-2 agonist used as a sedative, analgesic and centrally acting muscle relaxant in veterinary medicine
价 格:¥电议型 号:T1500产 地:美洲
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T15215EmiglitateEmiglitate,BAY o 1248,
Emiglitate is a selective and competitive α-glucoside hydrolase inhibitor.
价 格:¥电议型 号:T15215产 地:美洲
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T1529MiglitolMiglitol,BAY-m1099,BAY1099
Miglitol is an alpha-Glucosidase Inhibitor with antihyperglycemic activity.
价 格:¥电议型 号:T1529产 地:美洲
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T1537RapamycinRapamycin,AY 22989,Sirolimus
Rapamycin, a macrolide compound obtained from Streptomyces hygroscopicus, is a potent and specific mTOR inhibitor (IC50: 0.1 nM in HEK293 cells).
价 格:¥电议型 号:T1537产 地:美洲
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T15412GPP78GPP78,CAY10618,
GPP78 is cytotoxic to neuroblastoma cell line SH-SY5Y cells (IC50 of 3.8 nM by inducing autophagy). GPP78 is a potent inhibitor of Nampt (IC50 of 3.0 nM for nicotinamide adenine dinucleotide (NAD) depletion). GPP78 has anti-cancer and anti-inflammatory ef
价 格:¥电议型 号:T15412产 地:美洲
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T15766LirimilastLirimilast,BAY 19-8004,
Lirimilast is an effective, selective, and orally active phosphodiesterase-4 (PDE4) inhibitor (IC50: 49 nM). Lirimilast has potently anti-inflammatory properties. Lirimilast can be used for the treatment of asthma or chronic obstructive pulmonary disease.
价 格:¥电议型 号:T15766产 地:美洲
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T16016MaytansinolMaytansinol,Ansamitocin P-0,
Maytansinol inhibits microtubule assembly and causes microtubule disassembly in vitro.
价 格:¥电议型 号:T16016产 地:美洲
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T1617EnrofloxacinEnrofloxacin,PD160788,BAY-Vp2674
Enrofloxacin is a veterinary antibacterial agent, used in poultry.
价 格:¥电议型 号:T1617产 地:美洲
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T1640CiprofloxacinCiprofloxacin,Bay-09867,Bay o 9867
Ciprofloxacin, a synthetic broad spectrum fluoroquinolone antibiotic, inhibits bacterial DNA gyrase. It is more active against Gram-negative bacteria than Gram-positive bacteria.
价 格:¥电议型 号:T1640产 地:美洲
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T16781RogaratinibRogaratinib,BAY1163877,
Rogaratinib is an aberrant inhibitor of fibroblast growth factor receptor (FGFR). Rogaratinib is as an orally available, selective and potent inhibitor of FGFR-1, -2 and -3 kinase activity.
价 格:¥电议型 号:T16781产 地:美洲
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T16784RoniciclibRoniciclib,BAY 1000394,
Roniciclib is an inhibitor of pan-cyclin dependent kinase (IC50s: 5-25 nM for CDK1, CDK2, CDK3, CDK4, CDK7, and CDK9).
价 格:¥电议型 号:T16784产 地:美洲
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T1783LXR623LXR623,WAY 252623,
WAY-252623 (LXR-623) is an orally bioavailable and highly specifical synthetic modulator of LXR.
价 格:¥电议型 号:T1783产 地:美洲
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T1792RegorafenibRegorafenib,BAY 73-4506,Fluoro-Sorafenib
Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor (IC50s: 1.5/2.5/4.2/7/13/22 nM for RET/C-RAF/VEGFR2/c-Kit/VEGFR1/PDGFRβ).
价 格:¥电议型 号:T1792产 地:美洲
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T1902BAY 11-7082BAY 11-7082,BAY 11-7821,
BAY 11-7082, a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21.
价 格:¥电议型 号:T1902产 地:美洲
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T1934Bay 11-7085Bay 11-7085,BAY 11-7083,
BAY 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).
价 格:¥电议型 号:T1934产 地:美洲
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T1983CAY10603CAY10603,BML-281,HDAC6 Inhibitor
CAY10603 is a potent and selective inhibitor of HDAC6.
价 格:¥电议型 号:T1983产 地:美洲
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T1984CinaciguatCinaciguat,BAY 58-2667,
Cinaciguat (BAY 58-2667) is the first of a new class of soluble guanylate cyclase (sGC) activators in clinical development for acute decompensated heart failure.
价 格:¥电议型 号:T1984产 地:美洲
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T1992MertansineMertansine,Maytansinoid DM1,DM1
Mertansine refers to the thiol-containing maytansinoid, DM1 (N2’-deacetyl-N2’-(3-mercapto-1-oxopropyl)maytansine) attached to a monoclonal antibody through reaction of the thiol group with the SPP (N-succinimidyl 4-(2-pyridyldithio)) linker to create an a
价 格:¥电议型 号:T1992产 地:美洲