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T81837MCaE12A；化合物 MCaE12AMCaE12A
MCaE12A, a potent modulator of RyR2, enhances the channel´s sensitivity to cytoplasmic calcium concentrations, facilitating its opening. This compound serves as a critical instrument for examining RyR2 structure-to-function relationships and for modulating Ca2+ homeostasis and dynamics in cardiac cells [1].
价 格：￥电议型 号：T81837产 地：中国大陆
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T81836Mca-SEVNLDAEFK(Dnp)-NH2；化合物 Mca-SEVNLDAEFK(Dnp)-NH2Mca-SEVNLDAEFK(Dnp)-NH2
Mca-SEVNLDAEFK(Dnp)-NH2 is a fluorogenic substrate featuring a 7-methoxycoumarin moiety whose fluorescence is quenched by the adjacent 2,4-dinitrophenyl group through resonance energy transfer. This compound serves as a probe for assessing peptidase activity; enzymatic cleavage of the amide bond separating the fluorophore and quencher results in increased fluorescence. It is particularly useful for quantifying the activity of BACE-1 [1].
价 格：￥电议型 号：T81836产 地：中国大陆
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T81835MC-betaglucuronide-MMAE-2；化合物 MC-betaglucuronide-MMAE-2MC-betaglucuronide-MMAE-2
MC-betaglucuronide-MMAE-2 is an ADC (antibody-drug conjugate) agent-linker conjugate that exhibits potent antitumor activity; it consists of MMAE (a tubulin polymerization inhibitor) connected through the cleavable linker MC-betaglucuronide.
价 格：￥电议型 号：T81835产 地：中国大陆
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T81834MC-GGFG-(7ethanol-10NH2-11F-Camptothecin)；化合物 MC-GGFG-(7ethanol-10NH2-11F-Camptothecin)MC-GGFG-(7eth
MC-GGFG-(7ethanol-10NH2-11F-Camptothecin) (compound 141) is a protease-cleavable drug-linker conjugate utilized in antibody-drug conjugates (ADCs), featuring an MC-GGFG linker that allows for enzymatic cleavage [1].
价 格：￥电议型 号：T81834产 地：中国大陆
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T81833MC-GGFG-AM-(10NH2-11F-Camptothecin)；化合物 MC-GGFG-AM-(10NH2-11F-Camptothecin)MC-GGFG-AM-(10NH2-11F-Cam
MC-GGFG-AM-(10NH2-11F-Camptothecin) is an antibody-drug conjugate (ADC) that exhibits antitumor activity by targeting TROp-2 with the sacituzumab antibody through a hydrolysable, pH-sensitive linker. It is utilized in cancer research [1].
价 格：￥电议型 号：T81833产 地：中国大陆
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T81832MC-VC-PABC-C6-alpha-Amanitin；化合物 MC-VC-PABC-C6-alpha-AmanitinMC-VC-PABC-C6-alpha-Amanitin
MC-VC-PABC-C6-alpha-Amanitin is an antibody-drug conjugate that combines the anticancer toxin alpha-Amanitin with the monoclonal antibody MC-VC-PABC-C6. Alpha-Amanitin acts as a potent inhibitor of RNA polymerase IIα, enabling the conjugate to selectively target and recognize HER2-positive tumor cells. This specificity makes MC-VC-PABC-C6-alpha-Amanitin a valuable research tool in the study of breast and gastric cancers [1].
价 格：￥电议型 号：T81832产 地：中国大陆
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T81280Rha-PEG3-SMCC；化合物 Rha-PEG3-SMCCRha-PEG3-SMCC
Rha-PEG3-SMCC (Compound 13) serves as an ADC (antibody-drug conjugate) linkage agent with robust antitumor properties, utilizing the protein crosslinker SMCC, which is tethered through the non-cleavable linker Rha-PEG3.
价 格：￥电议型 号：T81280产 地：中国大陆
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T81263RMC-7977；化合物 RMC-7977RMC-7977
RMC-7977 is a highly selective inhibitor of the active (GTP-bound) forms of KRAS, HRAS, and NRAS with anticancer activity for the study of solid tumors with KRAS G12C mutations.
价 格：￥电议型 号：T81263产 地：中国大陆
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T81054T-1-MCPAB；化合物 T-1-MCPABT-1-MCPAB
T-1-MCPAB, a VEGFR-2 inhibitor with an IC50 of 0.135 ?M, effectively suppresses MCF7 cell migration and has applications in cancer research [1].
价 格：￥电议型 号：T81054产 地：中国大陆
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T81030Tauro-β-muricholic acid；化合物 Tauro-β-muricholic acidTβMCA；TβMCA
Tauro-β-muricholic acid (TβMCA), a trihydroxylated bile acid, acts as a competitive and reversible FXR antagonist (IC 50 = 40 μM) and exhibits antiapoptotic effects by inhibiting bile acid-induced hepatocellular apoptosis and preserving mitochondrial membrane potential [1] [2].
价 格：￥电议型 号：T81030产 地：中国大陆
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T80579Suvemcitug；化合物 SuvemcitugSuvemcitug
Suvemcitug, an IgG1κ antibody, specifically targets vascular endothelial growth factor (VEGF) and is derived from the African hare (Oryctolagus cuniculus) [1].
价 格：￥电议型 号：T80579产 地：中国大陆
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T80541TCMCB07 TFA；化合物 TCMCB07 TFATCMCB07 TFA
TCMCB07 TFA is a cyclic nonapeptide and an orally active, brain-penetrating antagonist of the melanocortin receptor 4 (MC4R), playing a significant role in managing cachexia [1].
价 格：￥电议型 号：T80541产 地：中国大陆
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T80540TCMCB07；化合物 TCMCB07TCMCB07
TCMCB07, a cyclic nonapeptide, serves as an orally active, brain-penetrant antagonist of the melanocortin receptor 4 (MC4R), with significant implications in the management of cachexia [1].
价 格：￥电议型 号：T80540产 地：中国大陆
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T80343MCF；化合物 MCFMCF
MCF, an antimicrobial peptide originating from bee venom, exhibits activity against E. coli W 160-37, S. aureus 8530, and B. subtilis, with minimum inhibitory concentration (MIC) values of 35-45 μg/ml, 25-35 μg/ml, and 15-25 μg/ml, respectively [1].
价 格：￥电议型 号：T80343产 地：中国大陆
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T80211Ac-KQL-AMC；化合物 Ac-KQL-AMCAc-KQL-AMC
Ac-KQL-AMC is a fluorogenic substrate designed for the quantification of Trypsin-like activity, emitting detectable fluorescence upon proteasomal cleavage [1].
价 格：￥电议型 号：T80211产 地：中国大陆
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T80122Dermcidin-1L (human)；化合物 Dermcidin-1L (human)Dermcidin-1L (human)
Dermcidin-1L (human), an antibiotic peptide secreted by sweat glands, exhibits antimicrobial activity and is utilized in the research of inflammatory skin disorders [1].
价 格：￥电议型 号：T80122产 地：中国大陆
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T80110Ac-VRPR-AMC；化合物 Ac-VRPR-AMCAc-VRPR-AMC
Ac-VRPR-AMC is a fluorogenic substrate for metacaspase activity assays, facilitating the detection and measurement of metacaspase activity [1].
价 格：￥电议型 号：T80110产 地：中国大陆
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T80107Tos-Gly-Pro-Lys-AMC；化合物 Tos-Gly-Pro-Lys-AMCTos-Gly-Pro-Lys-AMC
Tos-Gly-Pro-Lys-AMC is a fluorogenic peptide substrate that is specific for tryptase [1].
价 格：￥电议型 号：T80107产 地：中国大陆
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T80092Z-Gly-Pro-Arg-AMC hydrochloride；化合物 Z-Gly-Pro-Arg-AMC hydrochlorideZ-Gly-Pro-Arg-AMC hydrochloride
Z-Gly-Pro-Arg-AMC hydrochloride is a fluorescent substrate for both trypsin and cathepsin K, utilized to assay their respective enzymatic activities [1] [2].
价 格：￥电议型 号：T80092产 地：中国大陆
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T80048Mca-YVADAP-Lys(Dnp)-OH TFA；化合物 Mca-YVADAP-Lys(Dnp)-OH TFAMca-YVADAP-Lys(Dnp)-OH TFA
Mca-YVADAP-Lys(Dnp)-OH TFA serves as a fluorogenic substrate specifically utilized for caspase-1 and angiotensin-converting enzyme 2 (ACE2) [1].
价 格：￥电议型 号：T80048产 地：中国大陆
