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T8257Maduramicin ammonium;马杜霉素铵盐Maduramicin|||Maduramycin Ammonium;Maduramicin|||Maduramycin Ammonium|||马
Maduramicin ammonium (Maduramycin Ammonium) is an anticoccidial agent for the the treatment of Eimeria spp., E. adenoeides, E. gallopavonis, and E. dispersa infection
价 格:¥电议型 号:T8257产 地:中国大陆
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T81826Meayamycin D;化合物 Meayamycin DMeayamycin D
Meayamycin D, an analogue of FR901464, induces alternative splicing of MCL-1 and demonstrates a prolonged half-life in mouse plasma [1].
价 格:¥电议型 号:T81826产 地:中国大陆
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T81735Mycestericin C;化合物 Mycestericin CMycestericin C
Mycestericin C, isolated from Mycelia sterilia ATCC 20349 culture broth, inhibits lymphocyte proliferation in the mouse allogeneic mixed lymphocyte reaction [1].
价 格:¥电议型 号:T81735产 地:中国大陆
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T8118Bekanamycin;卡那霉素Kanamycin B;Kanamycin B|||卡那霉素|||卡那霉素 B
Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic.
价 格:¥电议型 号:T8118产 地:中国大陆
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T79942Terpenomycin;化合物 TerpenomycinTerpenomycin
Terpenomycin is a polyene compound isolated from pathogenic Nocardia terpenica strains in humans, exhibiting both cytotoxic and antifungal activities [1].
价 格:¥电议型 号:T79942产 地:中国大陆
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T79941Antimycin A2c;化合物 Antimycin A2cAntimycin A2c
Anticancer Agent 141 (Compound AE), an antimycin alkaloid, exhibits inhibitory potential against HPV-infected cervical cancer. It impedes HeLa cell proliferation by arresting the cell cycle at the S phase and induces caspase-dependent apoptosis through mitochondrial disruption. This disruption activates the ROS-mediated ubiquitin-dependent proteasome system, leading to the degradation of E6/E7 oncoproteins [1].
价 格:¥电议型 号:T79941产 地:中国大陆
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T7956022-(4′-py)-JA;化合物 22-(4′-py)-JA22-(4′-Pyridinecarbonyl) jorunnamycin A;22-(4′-Pyridinecarbonyl) joru
22-(4′-py)-JA, a semisynthetic derivative of junamycin A isolated from the Thai blue sponge (Xestospongia sp.), exhibits antimetastatic properties by inhibiting the AKT/mTOR/p70S6K signaling pathway. It also impedes tumor cell invasion and angiogenesis in human umbilical vein endothelial cells (HUVEC), while suppressing the expression of metalloproteinases (MMP-2 and MMP-9), hypoxia-inducible factor 1α (HIF-1α), and vascular endothelial growth factor (VEGF). Its potent anticancer activity is par
价 格:¥电议型 号:T79560产 地:中国大陆
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T79439c-Myc inhibitor 12;化合物 c-Myc inhibitor 12c-Myc inhibitor 12
Compound 67h, also known as c-Myc inhibitor 12, is a potent inhibitor of c-Myc, exhibiting a pEC50 value of 6.4 [1].
价 格:¥电议型 号:T79439产 地:中国大陆
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T79438c-Myc inhibitor 11;化合物 c-Myc inhibitor 11c-Myc inhibitor 11
c-Myc inhibitor 11 (Compound 67e), a c-MYC inhibitor (p EC 50 : 6.4), exhibits high clearance, a moderate volume of distribution, and a short half-life in rat pharmacokinetic assays, making it suitable for cancer research [1].
价 格:¥电议型 号:T79438产 地:中国大陆
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T79281Antimycobacterial agent-6;化合物 Antimycobacterial agent-6Antimycobacterial agent-6
Antimycobacterial agent-6 (compound 25) effectively inhibits Mycobacterium tuberculosis, including wild-type and fluoroquinolone-resistant strains, by targeting the Mtb DprE1-C387S mutant. It displays minimal inhibitory concentrations (MIC90) of 0.9 μM for H37Rv and MoxR strains, and 0.5 μM for the DprE1-P116S strain [1].
价 格:¥电议型 号:T79281产 地:中国大陆
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T78101Zymosan A酵母聚糖AZymosan A from Saccharomyces cerevisiae
Zymosan A, derived from Saccharomyces cerevisiae, is a TLR2 agonist and exhibits significant radioprotective effects, mitigating and preventing IR-induced intestinal injury in mice. Furthermore, Zymosan A aids in the regeneration of intestinal stem cells (ISCs) following IR injury [1].
价 格:¥电议型 号:T78101产 地:中国大陆
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T78055MYC-RIBOTAC;化合物 MYC-RIBOTACMYC-RIBOTAC
MYC-RIBOTAC, a ribonuclease-targeting chimera (RIBOTAC) specific to the MYC internal ribosome entry site (IRES), comprises an MYC mRNA-binding element tethered to a small molecule that recruits and activates RNase L1. This interaction promotes the degradation of MYC mRNA, subsequently reducing MYC protein levels and inducing apoptosis, thereby presenting potential applications in anticancer research [1].
价 格:¥电议型 号:T78055产 地:中国大陆
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T77814Tomaymycin DM;化合物 Tomaymycin DMTomaymycin DM
Tomaymycin DM, a derivative of Tomaymycin, functions as a DNA alkylator and PBD dimer. It is utilized to formulate antibody-drug conjugates (ADCs) by attaching to tumor-targeting antibodies.
价 格:¥电议型 号:T77814产 地:中国大陆
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T77215Kanamycins sulfate;化合物 Kanamycins sulfateKanamycins sulfate
Kanamycin sulfate, a broad-spectrum antibiotic, is effective for treating severe staphylococcal or Gram-negative bacillary infections. This compound has been linked to ototoxicity [1] [2].
价 格:¥电议型 号:T77215产 地:中国大陆
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T76448Arylomycin A2;化合物 Arylomycin A2Arylomycin A2
Arylomycin A2, a lipopeptide antibiotic, functions as a type I signal peptidase (SPase I) inhibitor. It exhibits antibacterial properties [1].
价 格:¥电议型 号:T76448产 地:中国大陆
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T76203Syringomycin E;化合物 Syringomycin ESyringomycin E
Syringomycin E, an antifungal cyclic lipodepsinonapeptide, inhibits the growth of Saccharomyces cerevisiae by interacting with the plasma membrane. It induces K+ efflux, Ca2+ influx, and alterations in membrane potential, associated with channel formation [1] [2].
价 格:¥电议型 号:T76203产 地:中国大陆
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T76000Aurantimycin A;化合物 Aurantimycin AAurantimycin A
Aurantimycin A (Adipogen), a depsipeptide antibiotic, exhibits potent efficacy against Gram-positive bacteria and serves as a substrate for the LieAB transporter [1] [2].
价 格:¥电议型 号:T76000产 地:中国大陆
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T75656Calcimycin hemimagnesium;化合物 Calcimycin hemimagnesiumCalcimycin hemimagnesium
Calcimycin (A-23187) hemimagnesium, an antibiotic and divalent cation ionophore (such as calcium and magnesium), serves various biological roles. It triggers Ca2+-dependent cell death by elevating intracellular calcium levels and suppresses the growth of Gram-positive bacteria and certain fungi. Additionally, this compound hinders ATPase activity and uncouples oxidative phosphorylation (OXPHOS) in mammalian cells, ultimately leading to apoptosis [1] [2] [3] [4].
价 格:¥电议型 号:T75656产 地:中国大陆
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T75634Demycarosyl-3D-β-D-digitoxosylmithramycin SK;化合物 Demycarosyl-3D-β-D-digitoxosylmithramycin SKDemycar
Demycarosyl-3D-β-D-digitoxosylmithramycin SK, an analog of Mithramycin, exhibits potent anti-tumor activity. It hinders tumor cell proliferation and growth by binding to and inhibiting DNA-binding proteins [1].
价 格:¥电议型 号:T75634产 地:中国大陆
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T7560123-O-Demycinosyltylosin;化合物 23-O-Demycinosyltylosin23-O-Demycinosyltylosin
23-O-Demycinosyltylosin (23-DMT), an acyl derivative of tylosin, exhibits antibacterial activity [1].
价 格:¥电议型 号:T75601产 地:中国大陆