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  • T40889DMNB-caged-Serine；DMNB-caged-SerineDMNB-caged-Serine

    DMNB-caged-Serine is a photocaged amino acid . DMNB is a caging group which is sensitive to blue light. DMNB-caged-Serine can be incorporated into proteins in Saccharomyces cerevisiae in response to the amber nonsense codon TAG, which can be helpful for controlling the chemical composition of mammalian proteins..

    价 格：￥电议型 号：T40889产 地：中国大陆

  • T40767Bananin；BananinBananin

    Bananin, a potent inhibitor of the ATPase activity exhibited by the SARS Coronavirus helicase, demonstrates remarkable efficacy with an IC50 value of 2.3 μM.

    价 格：￥电议型 号：T40767产 地：中国大陆

  • T40542Sinbaglustat；化合物SinbaglustatACT-519276|||Sinbaglustat|||OGT2378；ACT-519276|||Sinbaglustat|||OGT2378

    Sinbaglustat (OGT2378) (OGT2378) is a dual inhibitor of glucose ceramide synthetase (GCS) and non-lysosomal glucose ceramidase (GBA2).Sinbaglustat is an orally administered N-alkyl iminosugar that crosses the blood-brain barrier.Sinbaglustat is used for the treatment of lysosomal storage disorders and for the study of central neurodegenerative disorders associated with lysosomal dysfunction. Sinbaglustat is used for the treatment of lysosomal storage disorders and for the study of lysosomal dysf

    价 格：￥电议型 号：T40542产 地：中国大陆

  • T40394Benzamide-15NBenzamide-15NPhenylamide-15N|||Benzenecarboxamide-15N|||NSC-3114-15N|||Benzamide-15N

    Benzamide-15N (NSC-3114-15N) is a 15N-labeled Benzamide. Benzamide inhibits poly(ADP-ribose) polymerase (PARP).

    价 格：￥电议型 号：T40394产 地：中国大陆

  • T39915Trx-red；Trx-redTrx-red|||NBL-SS perchlorate；Trx-red|||NBL-SS perchlorate

    Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derived from the nile blue fluorophore. It is specifically designed for imaging thioredoxin (Trx) in live cells and in vivo, with excitation and emission wavelengths of 615 nm and 661 nm, respectively.

    价 格：￥电议型 号：T39915产 地：中国大陆

  • T39815anti-TNBC agent-1；anti-TNBC agent-1anti-TNBC agent-1

    anti-TNBC agent-1 is a highly effective compound specifically designed to target and combat triple-negative breast cancer (TNBC). It demonstrates remarkable potency against various breast cancer cell types, with IC50 values spanning from 0.20 μM to 0.27 μM. The mechanism of action of anti-TNBC agent-1 involves inducing apoptosis in SUM-159 cells through the mitochondria pathway, as well as causing G1 phase arrest in these cells.

    价 格：￥电议型 号：T39815产 地：中国大陆

  • T39739Bersiporocin；BersiporocinBersiporocin

    Bersiporocin, a prolyl-tRNA synthetase inhibitor, demonstrates potent activity with an IC50 of ≤100 nM against phosphoribosylpyrophosphate synthetase (PRS). This compound proves valuable for antifibrotic research.

    价 格：￥电议型 号：T39739产 地：中国大陆

  • T39680DiflomotecanDiflomotecanBN 80915

    Diflomotecan (BN 80915) is a potent, orally active topoisomerase I inhibitor that displays enhanced plasma stability and superior preclinical anti-tumor activity relative to other established compounds.

    价 格：￥电议型 号：T39680产 地：中国大陆

  • T39654Afimetoran；化合物AfimetoranBMS-986256；BMS-986256

    Afimetoran (BMS-986256) is a toll-like receptor antagonist. Afimetoran can be used in the research of inflammatory and autoimmune diseases.

    价 格：￥电议型 号：T39654产 地：中国大陆

  • T39630Zandatrigine；化合物ZandatrigineNBI-921352|||XEN901；NBI-921352|||XEN901

    Zandatrigine (NBI-921352) is a blocker of sodium channel protein type 8 subunit alpha and can be used in studies about nervous system pathologies of epilepsy treatment.

    价 格：￥电议型 号：T39630产 地：中国大陆

  • T39498Tofersen；TofersenBIIB067|||ISIS-SOD1Rx；BIIB067|||ISIS-SOD1Rx

    Tofersen (BIIB067) is an antisense oligonucleotide utilized to inhibit the synthesis of superoxide dismutase 1 (SOD1) protein by facilitating the degradation of SOD1 mRNA via the RNase H-dependent mechanism. This compound holds potential for amyotrophic lateral sclerosis (ALS) research.

    价 格：￥电议型 号：T39498产 地：中国大陆

  • T39463Asundexian；化合物AsundexianBAY 2433334|||Asundexian|||BAY2433334|||BAY-2433334；BAY 2433334|||Asundexian

    Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa, thereby inhibiting its activity.Asundexian has an IC50 of 1 nM for human FXIa in buffer.Asundexian has antitumor activity and may be useful in studies of Acute ischemic stroke, transient ischemic attack and ischemic stroke.

    价 格：￥电议型 号：T39463产 地：中国大陆

  • T39255β-Cyfluthrin；β-Cyfluthrinbeta-Cyfluthrin|||β-Cyfluthrin；beta-Cyfluthrin|||β-Cyfluthrin

    β-Cyfluthrin is a type II synthetic pyrethroid compound commonly utilized as an active ingredient in agricultural insecticide products. It exerts its insecticidal properties by acting as a neurotoxicant, primarily impacting the calcium concentration within nervous tissue. This effect is achieved through the inhibition of Ca 2+ ATPase, a crucial component involved in calcium transport.

    价 格：￥电议型 号：T39255产 地：中国大陆

  • T38863Luvadaxistat；化合物 LuvadaxistatTAK-831|||NBI 1065844；TAK-831|||NBI 1065844

    Luvadaxistat (TAK-831) is an orally active, potent and highly selective inhibitor of D-amino acid oxidase (DAAO) with an IC50 value of 14 nM for the oxidative deamination of D-serine.Luvadaxistat is used in the study of schizophrenia and cognitive disorders.

    价 格：￥电议型 号：T38863产 地：中国大陆

  • T38668endo-BCN-O-PNB；endo-BCN-O-PNBendo-BCN-O-PNB

    endo-BCN-O-PNB is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格：￥电议型 号：T38668产 地：中国大陆

  • T38360NBC 19NBC 19NBC 19

    Potent NLRP3 inflammasome inhibitor (IC50 = 60-80 nM). Inhibits nigericin- and ATP-induced IL-1β release.

    价 格：￥电议型 号：T38360产 地：中国大陆

  • T38101Bisucaberin；BisucaberinBisucaberin

    Bisucaberin is a siderophore and bacterial metabolite that has been found inA. haloplanktisand has anticancer activity.1,2It inhibits the growth of L1210 and 1MC carcinoma cells (IC50s = 9.7 and 12.7 μM, respectively) and sensitizes fibrosarcoma 1023 cells to macrophage-mediated cytolysis.

    价 格：￥电议型 号：T38101产 地：中国大陆

  • T37875Fenbendazole sulfone；Fenbendazole sulfoneFenbendazole sulfone

    Fenbendazole sulfone is a minor metabolite of the anthelmintic fenbendazole . Fenbendazole undergoes oxidation to form oxfendazole, which is further oxidized to form fenbendazole sulfone.

    价 格：￥电议型 号：T37875产 地：中国大陆

  • T37089Iclepertin；化合物 IclepertinBI-425809；BI-425809

    Iclepertin (BI-425809) is an orally active and selective inhibitor of glycine transporter protein 1 (GlyT1).Iclepertin is used for the treatment of central nervous system disorders such as Alzheimer;s disease. Iclepertin is used for central nervous system disorders such as Alzheimer;s disease, schizophrenia and cognitive disorders.

    价 格：￥电议型 号：T37089产 地：中国大陆

  • T36659BoromycinBoromycinBoromycin

    Boromycin is a boron-containing macrolide antibiotic that has been found in Streptomyces. Boromycin inhibits growth of B. subtilis (MIC = 0.05 μg/ml) and induces efflux of potassium ions from B. subtilis without affecting Na+/K+-ATPase activity. It decreases the synthesis of protein, RNA, and DNA in B. subtilis when used at a concentration of 0.05 μg/ml. It inhibits the growth of B. halodurans (MIC = 10 ng/ml) and inhibits the futalosine pathway of menaquinone synthesis in B. halodurans. Boromyc

    价 格：￥电议型 号：T36659产 地：中国大陆

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